The whole-genome landscape of medulloblastoma subtypes

Autor: Daniel Hübschmann, Olaf Witt, Eric Chuah, Michael Heinold, Andrey Korshunov, Zuguang Gu, Vyacheslav Amstislavskiy, Aaron H. Phillips, Matthias Bieg, David Finkelstein, Thomas Risch, Nikos Sidiropoulos, Peter Lichter, Tina Wong, Yanling Liu, Roland Eils, Barbara Hutter, Marc Zapatka, Sebastian M. Waszak, Charles D. Imbusch, Roger E. McLendon, Marie-Laure Yaspo, Susanne Gröbner, Volker Hovestadt, Ernest Fraenkel, Martin Ebinger, Florence M.G. Cavalli, Steven E. Schumacher, Hans-Jörg Warnatz, Amar Gajjar, Tobias Ehrenberger, Michael D. Taylor, Ivo Buchhalter, Kane Tse, Betty Luu, Ursula D. Weber, Christel Herold-Mende, Benedikt Brors, Vasilisa A. Rudneva, Barbara C. Worst, Scott L. Pomeroy, Jinghui Zhang, Martin U. Schuhmann, Marina Ryzhova, Stephan Wolf, Andrew J. Mungall, Xin Zhou, Matthias Schlesner, A. Sorana Morrissy, Nagarajan Paramasivam, Maia Segura-Wang, Jan Koster, Stefan M. Pfister, Joachim Weischenfeldt, Marcel Kool, Yoon Jae Cho, Kortine Kleinheinz, Natalie Jäger, Richard A. Moore, Toshihiro Kumabe, Rameen Beroukhim, David Capper, Vijay Ramaswamy, Gang Wu, Linda M. Liau, Francisco German Rodriguez Gonzalez, Xiaochong Wu, Karen Mungall, Jan O. Korbel, Christina Jäger-Schmidt, Alke Jugold, Serap Erkek, Andreas von Deimling, Richard W. Kriwacki, Steven J.M. Jones, Thomas Zichner, Paul A. Northcott, David T.W. Jones, Lukas Chavez, Till Milde, Jaume Mora, Marco A. Marra, Yussanne Ma, Naveed Ishaque, Nina Thiessen, Nada Jabado, Giles W. Robinson

Publikováno v: Nature
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
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Nature, vol 547, iss 7663
Northcott, P A, Buchhalter, I, Morrissy, A S, Hovestadt, V, Weischenfeldt, J, Ehrenberger, T, Gröbner, S, Segura-Wang, M, Zichner, T, Rudneva, V A, Warnatz, H J, Sidiropoulos, N, Phillips, A H, Schumacher, S, Kleinheinz, K, Waszak, S M, Erkek, S, Jones, D T W, Worst, B C, Kool, M, Zapatka, M, Jäger, N, Chavez, L, Hutter, B, Bieg, M, Paramasivam, N, Heinold, M, Gu, Z, Ishaque, N, Jäger-Schmidt, C, Imbusch, C D, Jugold, A, Hübschmann, D, Risch, T, Amstislavskiy, V, Gonzalez, F G R, Weber, U D, Wolf, S, Robinson, G W, Zhou, X, Wu, G, Finkelstein, D, Liu, Y, Cavalli, F M G, Luu, B, Ramaswamy, V, Wu, X, Koster, J, Ryzhova, M, Cho, Y J, Pomeroy, S L, Herold-Mende, C, Schuhmann, M, Ebinger, M, Liau, L M, Mora, J, McLendon, R E, Jabado, N, Kumabe, T, Chuah, E, Ma, Y, Moore, R A, Mungall, A J, Mungall, K L, Thiessen, N, Tse, K, Wong, T, Jones, S J M, Witt, O, Milde, T, Von Deimling, A, Capper, D, Korshunov, A, Yaspo, M L, Kriwacki, R, Gajjar, A, Zhang, J, Beroukhim, R, Fraenkel, E, Korbel, J O, Brors, B, Schlesner, M, Eils, R, Marra, M A, Pfister, S M, Taylor, M D & Lichter, P 2017, ' The whole-genome landscape of medulloblastoma subtypes ', Nature, vol. 547, no. 7663, pp. 311-317 . https://doi.org/10.1038/nature22973
Nature, 547(7663), 311-317. Nature Publishing Group
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
Fundació Sant Joan de Déu

Current therapies for medulloblastoma, a highly malignant childhood brain tumour, impose debilitating effects on the developing child, and highlight the need for molecularly targeted treatments with reduced toxicity. Previous studies have been unable

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d03562ad516087a63dac40fefb3d3cbf
https://doi.org/10.1038/nature22973

Author Correction : The landscape of genomic alterations across childhood cancers

Autor: Christian P. Kratz, Benedikt Brors, Manfred Gessler, Jan J. Molenaar, Sebastian M. Waszak, Dietmar R. Lohmann, Vasilisa A. Rudneva, Kristian W. Pajtler, Gideon Zipprich, Daniel Baumhoer, Roland Kappler, Michael Heinold, Matthias Schlesner, Birgit Burkhardt, Stefan Rutkowski, Ewa Koscielniak, Sander Lambo, Sebastian Bender, Stephan Wolf, Michaela Nathrath, Angela J. Waanders, Jürgen Eils, Barbara C. Worst, Angelika Eggert, Michael C. Frühwald, Susanne Gröbner, Cornelia Eckert, Barbara Hutter, Hendrik Witt, Yanling Liu, Paul A. Northcott, Maia Segura-Wang, Pablo Landgraf, Sebastian Brabetz, Danny A. Zwijnenburg, Jenny Wegert, Arndt Borkhardt, Marcel Kool, Gudrun Fleischhack, Renate Kirschner-Schwabe, Kortine Kleinheinz, Christof M. Kramm, Daniel Hübschmann, Pascal Johann, Simone Fulda, Dominik Sturm, Gunther Richter, Peter Lichter, Katja von Hoff, Michaela Kuhlen, Gilles Vassal, Jan O. Korbel, Johannes H. Schulte, Rosario M. Piro, Joachim Weischenfeldt, Reiner Siebert, Udo Kontny, Christian Lawerenz, Gnana Prakash Balasubramanian, David T.W. Jones, Charlotte M. Niemeyer, Uta Dirksen, Lukas Chavez, Serap Erkek, Adam C. Resnick, Frank Westermann, Stefan S. Bielack, Stefan M. Pfister, Ursula D. Weber, Xin Zhou, Marc Zapatka, Cornelis M. van Tilburg, Roland Eils, Jan Koster, Stefan Burdach, Simone Hettmer, Thomas Klingebiel, Andreas E. Kulozik, Olaf Witt, Ivo Buchhalter, Pichai Raman, Claudia Blattmann, Jinghui Zhang, Elke Pfaff

In this Article, author Benedikt Brors was erroneously associated with affiliation number '8' (Department of Developmental Neurobiology, St Jude Children's Research Hospital, Memphis, Tennessee, USA); the author's two other affiliations (affiliations

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34f873180f3cfb0fb7e1bf649604c489
https://www.ncbi.nlm.nih.gov/pubmed/29875405

ACEseq – allele specific copy number estimation from whole genome sequencing

Autor: Rabea Wagener, Daniel Hübschmann, Isabell Bludau, Michael Heinold, Zuguang Gu, Kensche P, Benedikt Brors, Michael Hummel, Matthias Schlesner, Cristina López, Wolfram Klapper, Inga Vater, Roland Eils, Reiner Siebert, Kortine Kleinheinz, Peter Möller

ACEseq is a computational tool for allele-specific copy number estimation in tumor genomes based on whole genome sequencing. In contrast to other tools it features GC-bias correction, unique replication timing-bias correction and integration of struc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6a2b6d1890f3069b73f3114bfe0b25
https://opus.bibliothek.uni-augsburg.de/opus4/frontdoor/index/index/docId/96402

A comprehensive assessment of somatic mutation detection in cancer using whole-genome sequencing

Autor: Matthew D. Eldridge, Sasithorn Chotewutmontri, Susanne Gröbner, Eivind Hovig, Ivo Gut, Minghui He, Hidewaki Nakagawa, Charlotte Anderson, Rafael Valdés-Mas, Lars Feuerbach, Sergi Beltran, Adam Butler, Nagarajan Paramasivam, John Douglas Mcpherson, Akihiro Fujimoto, Ann-Marie Patch, Ivo Buchhalter, Laurie Tonon, Stefan M. Pfister, Víctor Quesada, Jon W. Teague, Sabine Schmidt, David T. W. Jones, Sahil Seth, David Torrents, Singer Ma, Marta Gut, Semin Lee, Robert E. Denroche, Carlos López-Otín, Andy G. Lynch, David A. Wheeler, Takafumi N. Yamaguchi, Lucy Stebbings, Ruben M. Drews, Roland Eils, Marc Dabad, Tyler Alioto, Barbara Hutter, Rebecca Shepherd, Peter Lichter, Sigve Nakken, Daniel Vodak, Simon Heath, Rolf Kabbe, Christopher Previti, Paul T. Spellman, Nicola Waddell, Jared T. Simpson, John V. Pearson, Timothy Beck, Patrick S. Tarpey, Daniela S. Gerhard, Andrew Menzies, Francesc Castro Giner, Paolo Ribeca, Nicholas J. Harding, Liu Xi, Nicolle Diessl, Emanuele Raineri, Lawrence E. Heisler, Jonathan Hinton, Xose S. Puente, Cyriac Kandoth, Natalie Jäger, David T. Jones, Matthias Schlesner, Louis Letourneau, Sean M. Grimmond, Elias Campo, Peter J. Campbell, Keiran Raine, Lawrence Bower, Michael Heinold, Andrey Korshunov, Thomas J. Hudson, Anne Sophie Sertier, Benedikt Brors, Sophia Derdak, Paul C. Boutros, Myron Peto, John Zhang, Philip Ginsbach

Publikováno v: Recercat. Dipósit de la Recerca de Catalunya
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Nature communications, vol 6, iss 1
Scopus
RUO. Repositorio Institucional de la Universidad de Oviedo
Dipòsit Digital de la UB
Universidad de Barcelona
UPCommons. Portal del coneixement obert de la UPC
Universitat Politècnica de Catalunya (UPC)
RUO: Repositorio Institucional de la Universidad de Oviedo
Universidad de Oviedo (UNIOVI)
Nature Communications

Financial support was provided by the consortium projects READNA under grant agreement FP7 Health-F4- 2008-201418, ESGI under grant agreement 262055, GEUVADIS under grant agreement 261123 of the European Commission Framework Programme 7, ICGC-CLL thr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c50ea0ec3ca8190514a6be077f87e3b
http://hdl.handle.net/2445/120214

A Business Case for Feature-Oriented Requirements Engineering.

Autor: Rudorfer, Arnold, Stenzel, Tobias, Herold, Gerold

Publikováno v: IEEE Software; Sep2012, Vol. 29 Issue 5, p54-59, 6p, 2 Color Photographs, 1 Diagram, 2 Charts, 2 Graphs