Zobrazeno 1 - 10
of 269
pro vyhledávání: '"Michael Hausmann"'
Autor:
Avital Angel Korman, Vladimir Rapoport, Hadassa Rimonie Seged German, Naomi Nakash Niddam, Zeev Katzir, Michael Hausmann, Adi Leiba
Publikováno v:
Blood Pressure, Vol 33, Iss 1 (2024)
Purpose The Endocrine Society (ES) guidelines recommend screening for primary aldosteronism (PA) in high risk hypertensive patients presenting with at least one of seven criteria (resistant HTN, hypokalaemia, adrenal nodule, etc.) Although guidelines
Externí odkaz:
https://doaj.org/article/847af0d0dbc14cb7868499b3c23532ba
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 10, Pp 8152-8172 (2023)
The spatial organization of euchromatin (EC) and heterochromatin (HC) appears as a cell-type specific network, which seems to have an impact on gene regulation and cell fate. The spatial organization of cohesin should thus also be characteristic for
Externí odkaz:
https://doaj.org/article/d7ef0d980d3a4089a479fe68e6ad25c1
Autor:
Jonas Weidner, Charlotte Neitzel, Martin Gote, Jeanette Deck, Kim Küntzelmann, Götz Pilarczyk, Martin Falk, Michael Hausmann
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2018-2034 (2023)
The cell as a system of many components, governed by the laws of physics and chemistry drives molecular functions having an impact on the spatial organization of these systems and vice versa. Since the relationship between structure and function is a
Externí odkaz:
https://doaj.org/article/e7d1bad348bb4894b790baf70549be24
Publikováno v:
Genes, Vol 15, Iss 1, p 33 (2023)
The specific characteristics of k-mer words (2 ≤ k ≤ 11) regarding genomic distribution and evolutionary conservation were recently found. Among them are, in high abundance, words with a tandem repeat structure (repeat unit length of 1 bp to 3 bp
Externí odkaz:
https://doaj.org/article/aeb5d5e92fa64b53acd3c9cbc90c5703
Autor:
Harry Scherthan, Beatrice Geiger, David Ridinger, Jessica Müller, Diane Riccobono, Felix Bestvater, Matthias Port, Michael Hausmann
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1518 (2023)
Exposure to high acute doses of ionizing radiation (IR) can induce cutaneous radiation syndrome. Weeks after such radiation insults, keratinocyte nuclei of the epidermis exhibit persisting genomic lesions that present as focal accumulations of DNA do
Externí odkaz:
https://doaj.org/article/6ffc0c035531407d81a9525a2ae94ad5
Publikováno v:
Heliyon, Vol 8, Iss 12, Pp e12607- (2022)
A 76-year-old man was evaluated in our emergency department (ED) for right toe swelling and pain. His initial ED workup revealed volume overload, uncontrolled hypertension, slow atrial fibrillation, refractory hypokalemia, mixed metabolic alkalosis a
Externí odkaz:
https://doaj.org/article/2ccaecbf9a364637a967826b4952d599
Autor:
Sharmistha Chakraborty, Mayank Singh, Raj K. Pandita, Vipin Singh, Calvin S.C. Lo, Fransisca Leonard, Nobuo Horikoshi, Eduardo G. Moros, Deblina Guha, Clayton R. Hunt, Eric Chau, Kazi M. Ahmed, Prayas Sethi, Vijaya Charaka, Biana Godin, Kalpana Makhijani, Harry Scherthan, Jeanette Deck, Michael Hausmann, Arjamand Mushtaq, Mohammad Altaf, Kenneth S. Ramos, Krishna M. Bhat, Nitika Taneja, Chandrima Das, Tej K. Pandita
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104142- (2022)
Summary: Hyperthermia inhibits DNA double-strand break (DSB) repair that utilizes homologous recombination (HR) pathway by a poorly defined mechanism(s); however, the mechanisms for this inhibition remain unclear. Here we report that hyperthermia dec
Externí odkaz:
https://doaj.org/article/c0996799142844549be35341cfc4a7d5
Publikováno v:
Genes, Vol 14, Iss 3, p 755 (2023)
Dinucleotides are known as determinants for various structural and physiochemical properties of DNA and for binding affinities of proteins to DNA. These properties (e.g., stiffness) and bound proteins (e.g., transcription factors) are known to influe
Externí odkaz:
https://doaj.org/article/1e530d1a89e240f182c3cd02a54299d2
Autor:
Jekaterina Erenpreisa, Alessandro Giuliani, Kenichi Yoshikawa, Martin Falk, Georg Hildenbrand, Kristine Salmina, Talivaldis Freivalds, Ninel Vainshelbaum, Jonas Weidner, Aaron Sievers, Götz Pilarczyk, Michael Hausmann
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2658 (2023)
Complex functioning of the genome in the cell nucleus is controlled at different levels: (a) the DNA base sequence containing all relevant inherited information; (b) epigenetic pathways consisting of protein interactions and feedback loops; (c) the g
Externí odkaz:
https://doaj.org/article/cd07d7715fc249c2a93e85880cb9b313
Publikováno v:
Galaxies, Vol 10, Iss 5, p 101 (2022)
We aim to establish a rough first prospect on the potential of certain biorelevant solvents (water, ammonia, and methane) being present in liquid form inside the uppermost few meters of several modeled rocky and icy surfaces of hypothetical bodies or
Externí odkaz:
https://doaj.org/article/053a44a0b40c4f8594d6e653c64f2868