Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Michael H. Rock"'
Autor:
Michael H. Rock, Michèle Ourévitch, Abdelhakim Chennoufi, Danièle Bonnet-Delpon, Jean-Pierre Bégué, K. S. Ravikumar
Publikováno v:
Journal of Fluorine Chemistry. 107:275-279
The 1,3-dipolar cycloadditions of ethyltrifluorocrotonates to the azomethineylide, generated from 2-( tert -butyl)-3-methyl-imidazolin-4-one and formaldehyde, proceeds with a high degree of stereo- and regioselectivity to give precursors of 4-trifluo
Autor:
Sylvie Condon, Michael Rajaonah, Michael H. Rock, Jean-Yves Nédélec, Danièle Bonnet-Delpon, Jean-Pierre Bégué
Publikováno v:
Tetrahedron Letters. 39:3137-3140
An efficient electrochemical silylation of chlorodifluoromethyl enol ethers 2 afforded in good yields the new functionalized difluoromethyl allylsilanes 1 on a preparative scale. These silanes reacted as difluoromethyl anion equivalents with an aldeh
Publikováno v:
The Journal of Organic Chemistry. 63:2493-2496
The treatment of phenyl chloroformates 1 with a Lewis acid in the liquid phase resulted in decarboxylation to the corresponding chloroaromatics 2. Fluoroaromatic compounds were synthesized from phenylchloroformates 1 through a sequential fluorination
Publikováno v:
Synthesis. 1998:288-292
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1797-1800
Addition of lithium amides derived from a range of cyclic, sterically demanding, and chiral amines, to trifluoromethyl (Z)-enol ethers 1 and 4, provides stereoselectively the corresponding (Z)-enamines 3a–e and 7 in good yields. This reaction has b
Publikováno v:
Journal of Fluorine Chemistry. 80:17-20
Treatment of the 1-trifiuoromethyl enamines 1a-d with bromine or iodine results in the formation of the corresponding iminium salts. Treatment of any of these salts with methanol results in the formation of the corresponding α-halo-trifluoromethyl k
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :1409-1413
The treatment of α-(trifluoromethyl)styrene with organolithium reagents results in the selective formation of gem-difluoroalkenes in good-to-excellent yields. This reaction has been applied to the synthesis of 3-gem-difluoro-2-phenylallylic amines a
Publikováno v:
The Journal of Organic Chemistry. 61:9111-9114
Addition of organolithium reagents to trifluoromethyl enol ethers 1a−d and thio enol ethers 2a provided stereoselectively the corresponding trisubstituted fluoroalkenes 3a−d in 70−90% yields. The products could themselves react with organolithi
Publikováno v:
Tetrahedron Letters. 37:171-174
Trifluoromethyl enol ethers and thioenol ethers conjugated with an unsaturation in the β-position undergo addition/elimination reactions with organolithium reagents to yield the corresponding trifluoromethyl alkenes while preserving the geometry of
Publikováno v:
Tetrahedron. 51:10289-10302