Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Michael H. Chaitin"'
Publikováno v:
Molecular Brain Research. 77:125-130
In adult mouse retinas the standard form of the cell surface adhesion/receptor molecule CD44 is localized to Müller cell apical microvilli. In the rds (retinal degeneration slow) mouse, however, CD44 immunolabel is increased and distributed througho
Publikováno v:
Experimental Eye Research. 67:283-292
The distribution of the cell surface adhesion/receptor molecule CD44 was studied in retinas of the Royal College of Surgeons (RCS) rat which exhibits an inherited retinal dystrophy. In this animal model, the retinal pigment epithelium fails to phagoc
Publikováno v:
Developmental Brain Research. 94:92-98
It was previously demonstrated that the 90 kDa cell adhesion molecule CD44 is localized to Müller cell apical microvilli which project into the interphotoreceptor matrix in the adult retina. For the current report, the distribution of CD44 was studi
Publikováno v:
Experimental Eye Research. 58:359-365
The transmembrane glycoprotein CD44 is a cell adhesion molecule which has recently been localized in a variety of cell types. It mediates cell attachment to extracellular matrix components and also binds to the actin cytoskeleton within the cell. In
Autor:
Steve Jones, Brenden F. Murphy, Robert J. Wordinger, Katherine O'Rourke, Catherine Jomary, Michael H. Chaitin, Neeraj Agarwal
Publikováno v:
Biochemical and biophysical research communications. 225(1)
In the rds mutant mouse the photoreceptor cells differentiate normally for the first few postnatal days, with the inner segments projecting an extended cilium. However, outer segments fail to form and only rudimentary disks and opsin-laden vesicles a
Autor:
Michael H. Chaitin
Publikováno v:
Experimental eye research. 54(2)
A 9 + 0 cilium represents the only connection between the light-sensitive rod outer segment (ROS) and the visual cell body. Differentiation of a ROS derives from a remodeling of the plasma membrane at the distal end of the cilium. Prior to this event
Autor:
Michael H. Chaitin
Publikováno v:
Experimental eye research. 53(1)
An actin filament meshwork was recently demonstrated within the ciliary axoneme at the base of the photoreceptor outer segment (OS) in rat retina. Individual filaments of a uniform polarity extended from the cilium and entered into the bottom of the
Publikováno v:
Experimental Eye Research. 24:553-558
Rhodopsin from the retinas of dystrophic (RCS) and normal rats was extracted in 2% digitonin. With the bleaching of visual pigment samples by short exposures to orange light it is shown that no difference exists for the bleaching rates of the two rho
Publikováno v:
Experimental eye research. 49(1)
Extended vitamin A deficiency in the cat led to an abnormal appearance in the tapetal fundus with the formation of a dark brown streak centered on the area centralis. At this time rod sensitivity, as measured by the b-wave of the electroretinogram, w
Publikováno v:
Experimental eye research. 45(4)
Cats on a taurine-deficient diet were studied with imaging fundus reflectometry and full-field electroretinography. The pattern of rhodopsin loss and the natural history of the disease were determined from maps of the rhodopsin distribution in the ce