Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michael H. Mesches"'
Autor:
Allison E. Tipton, Yasmin Cruz Del Angel, Kathryn Hixson, Jessica Carlsen, Dana Strode, Nicolas Busquet, Michael H. Mesches, Marco I. Gonzalez, Eleonora Napoli, Shelley J. Russek, Amy R. Brooks‐Kayal
Publikováno v:
Ann Neurol
Annals of neurology, vol 94, iss 1
Annals of neurology, vol 94, iss 1
ObjectiveTemporal lobe epilepsy (TLE) is a progressive disorder mediated by pathological changes in molecular cascades and hippocampal neural circuit remodeling that results in spontaneous seizures and cognitive dysfunction. Targeting these cascades
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b313d9fbbfa42a4052456591a1d346fa
https://europepmc.org/articles/PMC10313781/
https://europepmc.org/articles/PMC10313781/
Autor:
James L. McGaugh, Larry Cahill, Michael H. Mesches, Marise B. Parent, Karin Coleman-Mesches, Juan A. Salinas
Publikováno v:
Plasticity in The Central Nervous System ISBN: 9781315789279
The central hypothesis is that emotionally arousing stimulation activates the amygdala and that activation results in modulation of the storage of acquired information. Although there is substantial evidence suggesting that memory storage, particular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25d9cebc91ee03eedef089bbcee830c2
https://doi.org/10.4324/9781315789279-2
https://doi.org/10.4324/9781315789279-2
Publikováno v:
Annals of Neurology. 61:411-426
Objective The contribution of seizures to cognitive changes remains controversial. We tested the hypothesis that a single episode of neonatal seizures (sNS) on rat postnatal day (P) 7 permanently impairs hippocampal-dependent function in mature (P60)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d65c6a7d0854af4973d2366ca42cb6d0
https://doi.org/10.1002/ana.21071
https://doi.org/10.1002/ana.21071
Autor:
Paula C. Bickford, Karen Heman, W.B Rowe, Greg M. Rose, Michael H. Mesches, D. A. Young, Thomas J. Gould
Publikováno v:
Brain Research Bulletin. 58:581-586
Motor skill learning in rats has been linked to cerebellar function as well as to cortical and striatal influences. The present study evaluated the contribution of the hippocampus to motor learning. Adult male rats received electrolytic lesions desig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff51be4ea1bb46616bbee20a9e676aa
https://doi.org/10.1016/s0361-9230(02)00832-8
https://doi.org/10.1016/s0361-9230(02)00832-8
Autor:
Douglas B. Holmes, Michael H. Mesches, Boris Sepesi, Carmelina Gemma, Paula C. Bickford, Kevin S. Choo
Publikováno v:
The Journal of Neuroscience. 22:6114-6120
Antioxidants and diets supplemented with foods high in oxygen radical absorbance capacity (ORAC) reverse age-related decreases in cerebellar beta-adrenergic receptor function. We examined whether this effect was related to the antioxidant capacity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bfa8370c60beb3033d3f8c227b97786
https://doi.org/10.1523/jneurosci.22-14-06114.2002
https://doi.org/10.1523/jneurosci.22-14-06114.2002
Publikováno v:
Neurobiology of Learning and Memory. 66:253-257
Extensive evidence suggests that many drugs and hormones influence memory storage by modulating training-induced release of norepinephrine (NE) within the amygdala. This experiment used in vivo microdialysis and high-performance liquid chromatography
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37ad16d3ada050b5b05a408242533bfb
https://doi.org/10.1006/nlme.1996.0067
https://doi.org/10.1006/nlme.1996.0067
Publikováno v:
Neurobiology of Learning and Memory. 66:324-340
The aim of these experiments was to determine whether impaired retention performance in aversively motivated tasks, induced by blockade of amygdala AMPA receptors, is due to influences on mechanisms underlying memory retrieval or to other influences
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb43dbbc931350631f3640f4fcf157b4
https://doi.org/10.1006/nlme.1996.0073
https://doi.org/10.1006/nlme.1996.0073
The impact of a single seizure on cognition remains controversial. We hypothesized that a single early-life seizure (sELS) on rat Postnatal Day (P) 7 would alter only hippocampus-dependent learning and memory in mature (P60) rats. The Morris water ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5442e05c41c5a2ee6861d6ed27bed115
https://europepmc.org/articles/PMC2586615/
https://europepmc.org/articles/PMC2586615/
Autor:
Michael H. Mesches, Carmelina Gemma, Matthew Fister, Michael Browning, Paula C. Bickford, Heather Stellwagen, Steven J. Coultrap
Publikováno v:
Neuroreport. 15(14)
Experimental, clinical, and epidemiologic studies indicate that non-steroidal anti-inflammatory drugs (NSAIDs) are beneficial in Alzheimer's disease and other neuroinflammatory processes. One possible mechanism is an interaction with peroxisome proli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8177b58170039923d38c78472315e4c5
https://pubmed.ncbi.nlm.nih.gov/15371745
https://pubmed.ncbi.nlm.nih.gov/15371745
Exogenous NGF restores endogenous NGF distribution in the brain of the cognitively impaired aged rat
Autor:
Michael H. Mesches, A.-Ch. Granholm, Paula C. Bickford, Sonya Juthberg, Gregory M. Rose, Michael Browning, Dave Albeck
Publikováno v:
Brain research. 967(1-2)
Alzheimer's disease and normal aging may impair retrograde transport of nerve growth factor (NGF) from cortical areas to basal forebrain cholinergic neurons. We demonstrate a relationship between performance in a spatial reference memory task and NGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eda888cf7fc1c5ad69551f1da5a741ad
https://pubmed.ncbi.nlm.nih.gov/12650994
https://pubmed.ncbi.nlm.nih.gov/12650994