Zobrazeno 1 - 10
of 357
pro vyhledávání: '"Michael H Lee"'
Autor:
Gregory T Walker, Araceli Perez-Lopez, Steven Silva, Michael H Lee, Elisabet Bjånes, Nicholas Dillon, Stephanie L Brandt, Romana R Gerner, Karine Melchior, Grant J Norton, Felix A Argueta, Frenchesca Dela Pena, Lauren Park, Victor A Sosa-Hernandez, Rodrigo Cervantes-Diaz, Sandra Romero-Ramirez, Monica Cartelle Gestal, Jose L Maravillas-Montero, Sean-Paul Nuccio, Victor Nizet, Manuela Raffatellu
Publikováno v:
eLife, Vol 13 (2024)
The chemokine CCL28 is highly expressed in mucosal tissues, but its role during infection is not well understood. Here, we show that CCL28 promotes neutrophil accumulation in the gut of mice infected with Salmonella and in the lung of mice infected w
Externí odkaz:
https://doaj.org/article/ce27aadb314c42c5a695971d140d6e54
Autor:
Rahul Kumar, Sushil Kumar, Claudia Mickael, Dara Fonseca Balladares, Kevin Nolan, Michael H. Lee, Linda Sanders, Julia Nilsson, Ari B. Molofsky, Rubin M. Tuder, Kurt R. Stenmark, Brian B. Graham
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
BackgroundSchistosomiasis is a common cause of pulmonary hypertension (PH) worldwide. Type 2 inflammation contributes to the development of Schistosoma-induced PH. Specifically, interstitial macrophages (IMs) derived from monocytes play a pivotal rol
Externí odkaz:
https://doaj.org/article/c4fa6ee4bd3349f19baf5bada146c57a
Autor:
Dara C. Fonseca Balladares, Biruk Kassa, Claudia Mickael, Rahul Kumar, Kevin Nolan, Thais C. F. Menezes, Michael H. Lee, Anthony M. Lau-Xiao, Ari B. Molofsky, Elina Wells, Brian B. Graham
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 17, p 9202 (2024)
Background: Schistosomiasis is a parasitic infection that can cause pulmonary hypertension (PH). Th2 CD4 T cells are necessary for experimental Schistosoma-PH. However, if T cells migrate to the lung to initiate, the localized inflammation that drive
Externí odkaz:
https://doaj.org/article/69d4f02fe86a45deb56aae1d8f57c07b
Autor:
Biruk Kassa, Dara C. Fonseca‐Balladares, Rahul Kumar, Michael H. Lee, Claudia Mickael, Linda Sanders, Kevin Nolan, Brian B. Graham
Publikováno v:
Pulmonary Circulation, Vol 14, Iss 1, Pp n/a-n/a (2024)
Abstract Whether all Schistosoma species cause pulmonary hypertension (PH) is unclear. Experimentally exposing mice to Schistosoma haematobium eggs caused PH, which was less severe than that induced by S. mansoni exposure. These findings align with t
Externí odkaz:
https://doaj.org/article/46ef8c2b319c48a4b72d155414d53fe3
Autor:
Brian B. Graham, Joan F. Hilton, Michael H. Lee, Rahul Kumar, Dara Fonseca Balladares, Farbod N. Rahaghi, Raúl San José Estépar, Claudia Mickael, Rodrigo Luís Barbosa Lima, Camila M.C. Loureiro, Juliana Lucena, Rudolf K.F. Oliveira, Ricardo de Amorim Corrêa
Publikováno v:
JHLT Open, Vol 1, Iss , Pp 100007- (2023)
Pulmonary arterial hypertension associated with schistosomiasis (SchPAH) and pulmonary arterial hypertension associated with portal hypertension (PoPAH) are lung diseases that develop in the presence of liver diseases. However, mechanistic pathways b
Externí odkaz:
https://doaj.org/article/3299026feb594a1cb3780fc79b26ce21
Autor:
Judith Behnsen, Hui Zhi, Allegra T. Aron, Vivekanandan Subramanian, William Santus, Michael H. Lee, Romana R. Gerner, Daniel Petras, Janet Z. Liu, Keith D. Green, Sarah L. Price, Jose Camacho, Hannah Hillman, Joshua Tjokrosurjo, Nicola P. Montaldo, Evelyn M. Hoover, Sean Treacy-Abarca, Benjamin A. Gilston, Eric P. Skaar, Walter J. Chazin, Sylvie Garneau-Tsodikova, Matthew B. Lawrenz, Robert D. Perry, Sean-Paul Nuccio, Pieter C. Dorrestein, Manuela Raffatellu
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Zinc is an essential cofactor for bacterial metabolism. Here, the authors show that the probiotic bacterium Escherichia coli Nissle 1917 utilizes the siderophore yersiniabactin as a zincophore, allowing the microbe to grow in zinc-limited media and t
Externí odkaz:
https://doaj.org/article/19617c74d04844b3a0b478ff2c84a9cf
Autor:
Michael H. Lee, Thaís C. F. Menezes, Julie A. Reisz, Eloara V. M. Ferreira, Brian B. Graham, Rudolf K. F. Oliveira
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Pulmonary arterial hypertension is an incurable disease marked by dysregulated metabolism, both at the cellular level in the pulmonary vasculature, and at the whole-body level characterized by impaired exercise oxygen consumption. Though both altered
Externí odkaz:
https://doaj.org/article/795a395e5114404493146bab8c48b38b
Publikováno v:
Southwest Journal of Pulmonary and Critical Care, Vol 23, Iss 1, Pp 18-22 (2021)
This is a case of a 55-year-old man with Roux-en-Y gastric bypass surgery 15 years prior who presented with acute pancreatitis and developed distributive shock, bacteremia, acute respiratory distress syndrome, anuric acute renal failure, and a disten
Externí odkaz:
https://doaj.org/article/34be8df6e2bd43c9b38007b6a490c189
Autor:
Sue Gu, Claudia Mickael, Rahul Kumar, Michael H. Lee, Linda Sanders, Biruk Kassa, Julie Harral, Jason Williams, Kirk C. Hansen, Kurt R. Stenmark, Rubin M. Tuder, Brian B. Graham
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 3, Pp n/a-n/a (2022)
Abstract Right ventricular (RV) failure is the primary cause of death in pulmonary hypertension (PH), but the mechanisms of RV failure are not well understood. We hypothesized macrophages in the RV contribute to the RV response in PH. We induced PH i
Externí odkaz:
https://doaj.org/article/783929df348a4cba9dd4c63c25ba23b0
Publikováno v:
Canadian Medical Education Journal (2022)
Externí odkaz:
https://doaj.org/article/4e0e6157d1f14ebc834c7c21e37a4f90