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pro vyhledávání: '"Michael Höcker"'
Vascular endothelial growth factor D has recently been linked to the control of lymphangiogenesis and lymphatic metastasis. The molecular determinants regulating vegf-D gene transcription, however, have not yet been identified. After isolation of 2 k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a714c155e053e2dc5dc55201328ee95d
https://doi.org/10.1158/0008-5472.c.6497631
https://doi.org/10.1158/0008-5472.c.6497631
Supplementary Tables 1-3 from Regulation of Vascular Endothelial Growth Factor D by Orphan Receptors Hepatocyte Nuclear Factor-4α and Chicken Ovalbumin Upstream Promoter Transcription Factors 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b884bd28cfc147e02d7ad2fe9ddbad4
https://doi.org/10.1158/0008-5472.22374891
https://doi.org/10.1158/0008-5472.22374891
Supplementary Table Legends from Regulation of Vascular Endothelial Growth Factor D by Orphan Receptors Hepatocyte Nuclear Factor-4α and Chicken Ovalbumin Upstream Promoter Transcription Factors 1 and 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5da1f08c5ef016109658882694c4db1f
https://doi.org/10.1158/0008-5472.22374894.v1
https://doi.org/10.1158/0008-5472.22374894.v1
Autor:
Michael Höcker, Erika Green, Sara Fish, Steven D. Brown, Elizabeth Daniele, Kenneth Chng, Simon Bailey, Kandaswamy Vijayan, Aleks Jamborcic, Peggy A. Thompson, Adam Kallel, Gregory S. Parker, Julia A. Toth, Geoffray Leriche
Publikováno v:
Cancer Research. 81:1283-1283
Targeted protein degradation using the endogenous Ubiquitin Proteasome System (UPS) represents a fundamentally new approach to drug discovery that potentially allows proteins that cannot be modulated by conventional small molecule inhibitors to be br
Publikováno v:
Cellular Oncology. 37:131-145
In the past, the vascular endothelial growth factor receptor-3 (VEGFR-3) has been linked to the regulation of lymphangiogenesis and the lymphatic spread of solid malignancies. The molecular mechanisms controlling VEGFR3 gene expression have, however,
Autor:
Wolfgang Kemmner, Christian Pilarsky, Mario Anders, Marion Fehlker, Michael Höcker, Christoph Wissmann, Qing Wang
Publikováno v:
Molecular Carcinogenesis. 52:29-38
Angiogenesis is a prerequisite for progression of cancers. The number of genes linked to angiogenesis suggests the existence of complex gene-networks, which remain to be elucidated. To identify angiogenesis genes deregulated in carcinomas, we perform
Autor:
S Lobitz, Katjana Daskalow, Thorsten Cramer, Nadine Rohwer, Thomas Jöns, Wolfgang Kemmner, Peter M. Schlag, M Vieth, Bertram Wiedenmann, Michael Höcker
Publikováno v:
British Journal of Cancer
Gastric adenocarcinoma is characterised by rapid emergence of systemic metastases, resulting in poor prognosis due to vanished curative treatment options. Better understanding of the molecular basis of gastric cancer spread is needed to design innova
Autor:
Michael Höcker, Matthias Pross, Stephan Gretschel, Matthias P.A. Ebert, Mario Anders, Michael Vieth, Bertram Wiedenmann, Peter M. Schlag, Wolfgang Kemmner, Christoph Röcken
Publikováno v:
British Journal of Cancer
Loss of the coxsackie and adenovirus receptor (CAR) has previously been observed in gastric cancer. The role of CAR in gastric cancer pathobiology, however, is unclear. We therefore analysed CAR in 196 R(0)-resected gastric adenocarcinomas and non-ca
Publikováno v:
Cancer Research. 68:457-466
Vascular endothelial growth factor D has recently been linked to the control of lymphangiogenesis and lymphatic metastasis. The molecular determinants regulating vegf-D gene transcription, however, have not yet been identified. After isolation of 2 k
Autor:
Wolfgang E. Schmidt, Stefan Jüttner, Thorsten Cramer, N Ansorge, Frank Schmitz, Michael Höcker
Publikováno v:
Regulatory Peptides. 144:25-33
Cyclooxygenase-2, the inducible enzyme of arachidonic acid metabolism and prostaglandin synthesis, is over expressed in colorectal cancer. Inhibition of COX-1/-2 by non-steroidal anti-inflammatory drugs is associated with a decreased risk for these m