The not so hidden impact of interictal burden in migraine: A narrative review

Autor: Maurice Vincent, Lars Viktrup, Robert A. Nicholson, Michael H. Ossipov, Bert B. Vargas

Publikováno v: Frontiers in Neurology, Vol 13 (2022)

Migraine is a highly prevalent neurological disease of varying attack frequency. Headache attacks that are accompanied by a combination of impact on daily activities, photophobia and/or nausea are most commonly migraine. The headache phase of a migra

Externí odkaz: https://doaj.org/article/5d717d930b334f39b8509c42eb40e931

The FDA Mandate to Reassess Benzodiazepines: Alprazolam Induces a Positive Conditioned Place-Preference in Male Rats

Autor: Tally M. Largent-Milnes, Sumiyo Umeda-Raffa, Robert B. Raffa, Austen Thompson, Michael H. Ossipov, Joseph V. Pergolizzi Junior, Cheyenne Moffett, Katherine J. Kost, Todd W. Vanderah

Publikováno v: Journal of Biosciences and Medicines. :1-8

On September 23, 2020, in order “To address the serious risks of abuse, addiction, physical dependence, and withdrawal reactions, the U.S. Food and Drug Administration (FDA) is requiring the Boxed Warning be updated for all benzodiazepine medicines

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3ee8d08669f09367fc30c079785c0029
https://doi.org/10.4236/jbm.2021.93001

Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds

Autor: Thomas Hansen, Jes Olesen, Mikkel Ammentorp Storm, Rie Bager Hansen, Michael H. Ossipov, David Møbjerg Kristensen, Frank Porreca, Sarah L Christensen, Jose M. G. Izarzugaza

Publikováno v: Christensen, S L, Hansen, R B, Storm, M A, Olesen, J, Hansen, T F, Ossipov, M, Izarzugaza, J M G, Porreca, F & Kristensen, D M 2020, ' Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds ', European Journal of Pain, vol. 24, no. 4, pp. 783-790 . https://doi.org/10.1002/ejp.1528
Christensen, S L, Hansen, R B, Storm, M A, Olesen, J, Hansen, T F, Ossipov, M, Izarzugaza, J M G, Porreca, F & Kristensen, D M 2020, ' Von Frey testing revisited: Provision of an online algorithm for improved accuracy of 50% thresholds ', European Journal of Pain, vol. 24, pp. 783–790 . https://doi.org/10.1002/ejp.1528

Background: In the pain field, it is essential to quantify nociceptive responses. The response to the application of von Frey filaments to the skin measures tactile sensitivity and is a surrogate marker of allodynia in states of peripheral and/or cen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aabdbd26986f0a67901560fcf0f2a9e1
https://doi.org/10.1002/ejp.1528

CGRP and the Trigeminal System in Migraine

Autor: Smriti Iyengar, Michael H. Ossipov, Sheena K. Aurora, Kirk W. Johnson

Publikováno v: Headache

Objective The goal of this narrative review is to provide an overview of migraine pathophysiology, with an emphasis on the role of calcitonin gene-related peptide (CGRP) within the context of the trigeminovascular system. Background Migraine is a pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d166c5595f683a833bc0c4949599cd3
http://europepmc.org/articles/PMC6593989

Lasmiditan mechanism of action – review of a selective 5-HT1F agonist

Autor: Michael H. Ossipov, Kirk W. Johnson, Helen Hochstetler, Ann Marie Hake, Andrew M. Blumenfeld, David B. Clemow

Publikováno v: The Journal of Headache and Pain
The Journal of Headache and Pain, Vol 21, Iss 1, Pp 1-13 (2020)

Migraine is a leading cause of disability worldwide, but it is still underdiagnosed and undertreated. Research on the pathophysiology of this neurological disease led to the discovery that calcitonin gene-related peptide (CGRP) is a key neuropeptide

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c05bcb286d61d831e71398f71dc84f
https://doi.org/10.1186/s10194-020-01132-3