Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Michael Guarnieri"'
Autor:
Erica Farrand, Harold R Collard, Michael Guarnieri, George Minowada, Lawrence Block, Mei Lee, Carlos Iribarren
Publikováno v:
PLoS ONE, Vol 18, Iss 3, p e0280342 (2023)
BackgroundEpidemiological studies of interstitial lung disease (ILD) are limited by small numbers and tertiary care bias. Investigators have leveraged the widespread use of electronic health records (EHRs) to overcome these limitations, but struggle
Externí odkaz:
https://doaj.org/article/c288e88ec196412c8925103900d8de64
Autor:
Betty M. Tyler, Michael Guarnieri
Publikováno v:
Veterinary Sciences, Vol 10, Iss 6, p 372 (2023)
Long-acting injectable (LAI) opioid formulations mitigate the harm profiles and management challenges associated with providing effective analgesia for animals. A single dose of a long-acting opioid analgesic can provide up to 72 h of clinically rele
Externí odkaz:
https://doaj.org/article/8aa69f3d36ba4b01a26a4d06d5a904dc
Autor:
Noam Schildhaus, Eliana Trink, Chirs Polson, Louis DeTolla, Betty M Tyler, George I Jallo, Sino Tok, Michael Guarnieri
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 6, Iss 1, Pp 43-47 (2014)
Background: The change in the reaction time of a tail or paw exposed to a thermal stimulus is a measure of nociceptive activity in laboratory animals. Tail-flick and plantar thermal sensitivity (Hargreaves) tests are non-invasive, minimize stress, an
Externí odkaz:
https://doaj.org/article/a3847808b230402689cb6014d834148f
Publikováno v:
Journal of Pharmacy and Bioallied Sciences, Vol 6, Iss 1, Pp 38-42 (2014)
Background: Long-acting therapy in laboratory animals offers advantages over the current practice of 2-3 daily drug injections. Yet little is known about the disintegration of biodegradable drug implants in rodents. Objective: Compare bioavailability
Externí odkaz:
https://doaj.org/article/3ca00b1cbee74ad4923fb4b3f443b72e
Autor:
Saadet Inan, Michael Guarnieri
Publikováno v:
Journal of Opioid Management. 17:5-7
In 2005, Bob Adams, the Chief Veterinarian at Johns Hopkins, wondered if sustained release technology could be used to improve postsurgical analgesia for animal medicine. Henry Brem, Director of the Hunterian Laboratories, had organized an internatio
Autor:
Laura C. Myers, Dustin Mark, Brett Ley, Michael Guarnieri, Melinda Hofmeister, Shirley Paulson, Gregory Marelich, Vincent X. Liu
Publikováno v:
Critical care medicine. 50(7)
The respiratory rate-oxygenation (ROX) index is a fraction of oxygen saturation, Fio2, and respiratory rate that has been validated to predict receipt of invasive mechanical ventilation in patients receiving high-flow nasal cannula (HFNC). This study
Publikováno v:
ACS synthetic biology. 11(1)
Autor:
Michael Guarnieri
Publikováno v:
Journal of opioid management. 17(7)
Opioids, the frontline drugs for postsurgical analgesia, have been linked to diversion and abuse with lethal consequences. The search for safe analgesics with less harm potential has been decades long. However, clinical trials for safe opioid and non
Autor:
Rebecca Abergel, Parul Adams, Dion Antonopoulos, Gyorgy Babnigg, Scott Baker, Daniel Bedinger, Monica Borucki, Steven Bradfute, Thomas Bunt, Chris Daum, Joseph Fitch, Vince Gerbasi, Paul Gilna, David Graham, Michael Guarnieri, Sally Hall, Nathan Hillson, Elizabeth Hong-Geller, Greg Hura, Crystal Jaing, Ramesh Jha, Andrzej Joachimiak, Bishoy Kamel, Jeff Kimbrel, Antonietta Lillo, Betty Mangadu, Robert Meagher, Joseph Moon, Nigel Mouncey, Michael Morrison, Nisha Mulakken, Hau Nguyen, Marit Nilsen-Hamilton, Kristin Omberg, Hugh O'Neal, Jerry Parks, Lili Pasa-Tolic, Christa Pennacchio, Dave Rakestraw, Scott Retterer, Marc Salit, Blake Simmons, Anup Singh, Jess Sustarich, James Thissen, Nileena Velappan, Geoffrey Waldo, Kelly Williams, Jesse Wilson, Chunyan Ye, Malin Young, Yuko Yoshinaga, Mowei Zhou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b557fb404565249c2b2d9a6c10e3c577
https://doi.org/10.2172/1807806
https://doi.org/10.2172/1807806
Publikováno v:
Current medical research and opinion. 37(1)
Regulations for new drug approvals require stringent safety testing and efficacy trial programs. The approval process for generic drugs, however, is significantly streamlined. Bioavailability data can substitute for new rounds of efficacy trials, the