Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Michael Grunstein"'
Publikováno v:
PLoS ONE, Vol 4, Iss 3, p e4721 (2009)
BACKGROUND: Nucleosome free regions (NFRs) play important roles in diverse biological processes including gene regulation. A genome-wide quantitative portrait of each individual NFR, with their starting and ending positions, lengths, and degrees of n
Externí odkaz:
https://doaj.org/article/4856f8ba5fce421a8f9ebada43b4bcf8
Autor:
Tommy Kaplan, Chih Long Liu, Judith A Erkmann, John Holik, Michael Grunstein, Paul D Kaufman, Nir Friedman, Oliver J Rando
Publikováno v:
PLoS Genetics, Vol 4, Iss 11, p e1000270 (2008)
Acetylation of histone H3 lysine 56 is a covalent modification best known as a mark of newly replicated chromatin, but it has also been linked to replication-independent histone replacement. Here, we measured H3K56ac levels at single-nucleosome resol
Externí odkaz:
https://doaj.org/article/794b2f9fa1af4936b168527a3a1657ab
Publikováno v:
Wednesday, April 26.
Publikováno v:
Acta Scientific Neurology. 3:20-21
Autor:
Michael Grunstein, C. David Allis
Publikováno v:
JAMA. 320(12)
Publikováno v:
Proceedings of the National Academy of Sciences. 110:11493-11498
The presence of acetylated histone H3K56 (H3K56ac) in human ES cells (ESCs) correlates positively with the binding of Nanog, Sox2, and Oct4 (NSO) transcription factors at their target gene promoters. However, the function of H3K56ac there has been un
Autor:
Nancy Tran, Tasuku Kitada, Chunying Song, Yong Xue, Michael Carey, Michael Grunstein, Benjamin G. Kuryan
Publikováno v:
Genes & Development. 26:2443-2455
Yeast contains heterochromatin at telomeres and the silent mating-type loci (HML/HMR). Genes positioned within the telomeric heterochromatin of Saccharomyces cerevisiae switch stochastically between epigenetically bistable ON and OFF expression state
Publikováno v:
Proceedings of the National Academy of Sciences. 108:12693-12698
DNA topoisomerases are believed to promote transcription by removing excessive DNA supercoils produced during elongation. However, it is unclear how topoisomerases in eukaryotes are recruited and function in the transcription pathway in the context o
Autor:
Karl Ekwall, A. Francis Stewart, Indranil Sinha, Mickaël Durand-Dubief, Michael Grunstein, Andrej Shevchenko, Luke Buchanan, Michelle Rönnerblad, Carolina Bonilla
Publikováno v:
Epigenomics. 2:377-393
Aims: To map histone modifications with unprecedented resolution both globally and locus-specifically, and to link modification patterns to gene expression. Materials & methods: Using correlations between quantitative mass spectrometry and chromatin
Autor:
Adam S. Sperling, Michael Grunstein
Publikováno v:
Proceedings of the National Academy of Sciences. 106:13153-13159
In budding yeast, telomeres and the mating type (HM) loci are found in a heterochromatin-like silent structure initiated by Rap1 and extended by the interaction of Silencing Information Regulator (Sir) proteins with histones. Binding data demonstrate