Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Michael Grooms"'
Autor:
Feilan Wang, Kyung O. Johanson, Heather Fenderson, Robert B. Kirkpatrick, Gilbert F. Scott, Michael A. Pratta, Craig Volker, Michael Grooms, John A. Feild
Publikováno v:
Protein Expression and Purification. 50:102-110
Interleukin 1beta (IL-1beta) is a potent stimulator of extracellular matrix degradation in models of osteoarthritis (OA). In contrast to bovine explant models which effectively respond to recombinant human IL-1beta, canine models are relatively refra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::989d61722f89e232d4b4689a4dbdc65b
https://doi.org/10.1016/j.pep.2006.05.022
https://doi.org/10.1016/j.pep.2006.05.022
Autor:
Kurt R. Auger, Zhihong Lai, Michael Grooms, Thau F. Ho, Kyung O. Johanson, Robert A. Copeland, Peter J. Tummino, Robert B. Kirkpatrick, John D. Martin, Hong Zhang, Jianhong Ma
Publikováno v:
Biochemistry. 45:9238-9245
Mdm2 negatively regulates p53 by inhibiting its transcriptional activity and promoting its degradation by functioning as an E3 ubiquitin ligase. The primary p53 binding site on mdm2 is located in its N-terminal domain. Through binding to p53 at its N
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce02de64b96a92264ce4ba5b751d3bd
https://doi.org/10.1021/bi060661u
https://doi.org/10.1021/bi060661u
Autor:
Robert A. Copeland, Zhihong Lai, Tia Lewis, Kang Yan, Peter J. Tummino, Lata T. Gooljarsingh, John J. Kerrigan, Robert H. Sinnamon, Kyung O. Johanson, Christine Fernandes, Marc R. Arnone, Michael Grooms, Hong Zhang, Alastair J. King, Robert B. Kirkpatrick
Publikováno v:
Proceedings of the National Academy of Sciences. 103:7625-7630
Heat shock protein (Hsp)90 is emerging as an important therapeutic target for the treatment of cancer. Two analogues of the Hsp90 inhibitor geldanamycin are currently in clinical trials. Geldanamycin (GA) and its analogues have been reported to bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbf9463212847a9e81115d757c99e1fd
https://doi.org/10.1073/pnas.0602650103
https://doi.org/10.1073/pnas.0602650103
Autor:
Fevzi Daldal, Michael Grooms, Hannu Myllykallio, Clive A. Slaughter, Kevin A. Gray, Carolyn R. Moomaw
Publikováno v:
Biochemistry. 33:3120-3127
The facultative phototrophic bacterium Rhodobacter capsulatus is capable of growth in a wide range of environmental conditions using a highly branched electron-transfer chain. During respiratory growth of this organism reducing equivalents are convey
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89b419b49297390188f2c2c05e7aa1eb
https://doi.org/10.1021/bi00176a047
https://doi.org/10.1021/bi00176a047
Autor:
Michael Grooms, Robert A. Daines, Sanjay S. Khandekar, Cheryl A. Janson, Xiayang Qiu, John T. Lonsdale, Anthony E. Choudhry
Publikováno v:
Protein science : a publication of the Protein Society. 14(8)
β-Ketoacyl-ACP synthase III (FabH), an essential enzyme for bacterial viability, catalyzes the initiation of fatty acid elongation by condensing malonyl-ACP with acetyl-CoA. We have determined the crystal structure of FabH from Staphylococcus aureus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e51bfef6b655bcef92233339d384938
https://pubmed.ncbi.nlm.nih.gov/15987898
https://pubmed.ncbi.nlm.nih.gov/15987898
Publikováno v:
Photosynthesis: from Light to Biosphere ISBN: 9789401065627
Photosynthesis: from Light to Biosphere
Photosynthesis: from Light to Biosphere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24979850a986c4b839a8ef266781edcc
https://doi.org/10.1007/978-94-009-0173-5_420
https://doi.org/10.1007/978-94-009-0173-5_420
