Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Michael Grol"'
Publikováno v:
Advanced Science, Vol 11, Iss 22, Pp n/a-n/a (2024)
Abstract Pigments such as anthraquinones (AQs) and melanins are antioxidants, protectants, or virulence factors. AQs from the entomopathogenic bacterium Photorhabdus laumondii are produced by a modular type II polyketide synthase system. A key enzyme
Externí odkaz:
https://doaj.org/article/cce2ca2818f644139bcc9617ab6661b7
Autor:
Marietta S. Kaspers, Vivian Pogenberg, Christian Pett, Stefan Ernst, Felix Ecker, Philipp Ochtrop, Michael Groll, Christian Hedberg, Aymelt Itzen
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-15 (2023)
Abstract Bacterial pathogens often make use of post-translational modifications to manipulate host cells. Legionella pneumophila, the causative agent of Legionnaires disease, secretes the enzyme AnkX that uses cytidine diphosphate-choline to post-tra
Externí odkaz:
https://doaj.org/article/24651e6d5226410298bde574e8f3a727
Autor:
Werner Stock, Michael Grol, Dieter Neumeier, Peter Gudat, Thomas Kaiser, Gunter Pappert, Peter B. Luppa
Publikováno v:
Analytical Biochemistry. 282:173-185
Systematic ligand-binding studies of the biospecific interaction between steroids and antisteroid antibodies can be performed in real time using biosensor techniques. In this study, quartz crystal microbalance (QCM) and surface plasmon resonance (SPR
Autor:
Tad A. Holak, Dirk Demuth, Carola Dony, Markus Zweckstetter, Christian Renner, Michael Grol, Ralf Schumacher, Kurt Lang, Wenzel Kalus, Julia Georgescu, Yolanda Sanchez
Publikováno v:
EMBO Journal
Binding proteins for insulin-like growth factors (IGFs) IGF-I and IGF-II, known as IGFBPs, control the distribution, function and activity of IGFs in various cell tissues and body fluids. Insulin-like growth factor-binding protein-5 (IGFBP-5) is know
Autor:
Melanie Baudrexl, Tarik Fida, Berkay Berk, Wolfgang H. Schwarz, Vladimir V. Zverlov, Michael Groll, Wolfgang Liebl
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2022)
Functional, biochemical, and preliminary structural properties are reported for three glycoside hydrolases of the recently described glycoside hydrolase (GH) family 159. The genes were cloned from the genomic sequences of different Caldicellulosirupt
Externí odkaz:
https://doaj.org/article/ab7d23403b10415891edc142e63d4a11
Autor:
Mona Baumgart, Michael Röpke, Max E. Mühlbauer, Sam Asami, Sophie L. Mader, Kai Fredriksson, Michael Groll, Ana P. Gamiz-Hernandez, Ville R. I. Kaila
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Buried charged networks in proteins are often important for their biological functionality and are believed to destabilise the protein fold. Here, the authors combine computational design, MD simulations, biophysical experiments, NMR and X-ray crysta
Externí odkaz:
https://doaj.org/article/0e77cdff4a874a32b8c39f0694e34a3c
Autor:
Florian Dr. Binder, Reinhold Dr Hilpert, Hans-Peter Dr Josel, Helmut Oberpriller, Klaus Hallermayer, Christian Klein, Frieder W. Scheller, Josef Ritter, Michael Grol, Josef Maier
Publikováno v:
SPIE Proceedings.
In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portabledevices for the detection of illegal drugs, based on biosensor technology, are being developed. Theconcept comprises enrichment of the drug from the g
Autor:
Florian Dr. Binder, Christian G. Bauer, Hans-Peter Dr Josel, Josef Ritter, Reinhold Dr Hilpert, Helmut Oberpriller, Christian Klein, Klaus Hallermayer, Alexander Makower, Josef Maier, Michael Grol
Publikováno v:
SPIE Proceedings.
In a joint project of Deutsche Aerospace, Boehringer Mannheim and the University of Potsdam portable devices for the detection of illegal drugs, based on biosensor technology, are being developed. The concept enrichment of the drug from the gas phase
Autor:
Malvina Vogler, Ram Karan, Dominik Renn, Alexandra Vancea, Marie-Theres Vielberg, Stefan W. Grötzinger, Priya DasSarma, Shiladitya DasSarma, Jörg Eppinger, Michael Groll, Magnus Rueping
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Environments previously thought to be uninhabitable offer a tremendous wealth of unexplored microorganisms and enzymes. In this paper, we present the discovery and characterization of a novel γ-carbonic anhydrase (γ-CA) from the polyextreme Red Sea
Externí odkaz:
https://doaj.org/article/e2f6f414774945e7a023b8eb9c250b8a
Autor:
Pamina Kazman, Marie-Theres Vielberg, María Daniela Pulido Cendales, Lioba Hunziger, Benedikt Weber, Ute Hegenbart, Martin Zacharias, Rolf Köhler, Stefan Schönland, Michael Groll, Johannes Buchner
Publikováno v:
eLife, Vol 9 (2020)
In systemic light chain amyloidosis, an overexpressed antibody light chain (LC) forms fibrils which deposit in organs and cause their failure. While it is well-established that mutations in the LC’s VL domain are important prerequisites, the mechan
Externí odkaz:
https://doaj.org/article/7abca921f3e74dd78a0b33e60cc6f525