Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Michael Graner"'
Autor:
Wenbo Zhou, Michael Graner, Petr Paucek, Cheryl Beseler, Matthew Boisen, Andrew Bubak, Francisco Asturias, Woro George, Arin Graner, David Ormond, Timothy Vollmer, Enrique Alvarez, Xiaoli Yu
Publikováno v:
Cell Death and Disease, Vol 14, Iss 4, Pp 1-12 (2023)
Abstract Grey matter pathology is central to the progression of multiple sclerosis (MS). We discovered that MS plasma immunoglobulin G (IgG) antibodies, mainly IgG1, form large aggregates (>100 nm) which are retained in the flow-through after binding
Externí odkaz:
https://doaj.org/article/569999a6198440cb9d3ad26a27af33e5
Publikováno v:
Frontiers in Neurology, Vol 11 (2020)
The presence of persistent intrathecal oligoclonal immunoglobulin G (IgG) bands (OCBs) and lesional IgG deposition are seminal features of multiple sclerosis (MS) disease pathology. Despite extensive investigations, the role of antibodies, the produc
Externí odkaz:
https://doaj.org/article/149bd59013c847fa9f5355f9078ed90d
Autor:
Michael Graner, Tiffany Pointon, Sean Manton, Miyoko Green, Kathryn Dennison, Mollie Davis, Gino Braiotta, Julia Craft, Taylor Edwards, Bailey Polonsky, Anthony Fringuello, Timothy Vollmer, Xiaoli Yu
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228883 (2020)
IgG oligoclonal bands (OCBs) are present in the cerebrospinal fluid (CSF) of more than 95% of patients with multiple sclerosis (MS), and are considered to be the immunological hallmark of disease. However, the target specificities of the IgG in MS OC
Externí odkaz:
https://doaj.org/article/30d4034ea0b747c087a31186f0d7395b
Autor:
María Yáñez-Mó, Pia R.-M. Siljander, Zoraida Andreu, Apolonija Bedina Zavec, Francesc E. Borràs, Edit I. Buzas, Krisztina Buzas, Enriqueta Casal, Francesco Cappello, Joana Carvalho, Eva Colás, Anabela Cordeiro-da Silva, Stefano Fais, Juan M. Falcon-Perez, Irene M. Ghobrial, Bernd Giebel, Mario Gimona, Michael Graner, Ihsan Gursel, Mayda Gursel, Niels H. H. Heegaard, An Hendrix, Peter Kierulf, Katsutoshi Kokubun, Maja Kosanovic, Veronika Kralj-Iglic, Eva-Maria Krämer-Albers, Saara Laitinen, Cecilia Lässer, Thomas Lener, Erzsébet Ligeti, Aija Linē, Georg Lipps, Alicia Llorente, Jan Lötvall, Mateja Manček-Keber, Antonio Marcilla, Maria Mittelbrunn, Irina Nazarenko, Esther N.M. Nolte-‘t Hoen, Tuula A. Nyman, Lorraine O'Driscoll, Mireia Olivan, Carla Oliveira, Éva Pállinger, Hernando A. del Portillo, Jaume Reventós, Marina Rigau, Eva Rohde, Marei Sammar, Francisco Sánchez-Madrid, N. Santarém, Katharina Schallmoser, Marie Stampe Ostenfeld, Willem Stoorvogel, Roman Stukelj, Susanne G. Van der Grein, M. Helena Vasconcelos, Marca H. M. Wauben, Olivier De Wever
Publikováno v:
Journal of Extracellular Vesicles, Vol 4, Iss 0, Pp 1-60 (2015)
In the past decade, extracellular vesicles (EVs) have been recognized as potent vehicles of intercellular communication, both in prokaryotes and eukaryotes. This is due to their capacity to transfer proteins, lipids and nucleic acids, thereby influen
Externí odkaz:
https://doaj.org/article/81410b260f724df3a5b0ed8e77723836
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186842 (2017)
Intrathecal immunoglobulin G (IgG) and oligoclonal bands (OCBs) are the most consistent and characteristic features of Multiple Sclerosis (MS). OCBs in MS are considered products of clonally expanded B cells in the cerebrospinal fluid (CSF), represen
Externí odkaz:
https://doaj.org/article/5d8b0a11229f4fb497b63d962f808fe5
Autor:
Wenbo Zhou, Daniel Lovasz, Zoë Zizzo, Qianbin He, Christina Coughlan, Robert Kowalski, Peter Kennedy, Arin Graner, Kevin Lillehei, D. Ormond, A. Youssef, Michael Graner, Xiaoli Yu
Publikováno v:
Biomedicines; Volume 10; Issue 11; Pages: 2718
Glioblastoma (GBM) is the most aggressive and lethal form of brain tumor. Extracellular vesicles (EVs) released by tumor cells play a critical role in cellular communication in the tumor microenvironment promoting tumor progression and invasion. We h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03baf1167473fc5bd8e0ecc3e9ba7696
https://pubmed.ncbi.nlm.nih.gov/36359238
https://pubmed.ncbi.nlm.nih.gov/36359238
Autor:
Philip D. Tatman, Tadeusz Wroblewski, Anthony Fringurello, Sam Scherer, Will Foreman, Denise Damek, Kevin Lillehei, Samy Youssef, Ryan Ormond, Michael Graner
Publikováno v:
31st Annual Meeting North American Skull Base Society.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f967fd3b5faf9395824813bdb4ea873
https://doi.org/10.1055/s-0042-1743627
https://doi.org/10.1055/s-0042-1743627
Autor:
Denise Damek, David Ormond, Michael Graner, Tadeusz Wroblewski, Philip D. Tatman, Samy Youssef, Sam Scherer, Anthony Fringuello, William Foreman, Kevin O. Lillehei
Publikováno v:
Neuro Oncol
BACKGROUND Chordoma is a rare malignant tumor with poor surgical control and no existing pharmacotherapies. Therefore, these tumors require additional research into novel therapeutics for their treatment. METHODS In this study we created a high-throu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9ea11c63938f8580b32d16be52e2f04
https://doi.org/10.1093/neuonc/noab196.327
https://doi.org/10.1093/neuonc/noab196.327
Autor:
Zhe Wang, Peter GE Kennedy, Cecily Dupree, Min Wang, Catherin Lee, Tiffany Pointon, T. Dianne Langford, Michael Graner, Xiaoli Yu
Background Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system (CNS), the etiology of which is poorly understood. The most common laboratory abnormality associated with MS is increased intrathecal IgG
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9759f6a77e73074241eb5aafff97dc39
https://doi.org/10.21203/rs.3.rs-17090/v1
https://doi.org/10.21203/rs.3.rs-17090/v1
Autor:
Philip D. Tatman, Sam Scherer, Denise Damek, William Foreman, Michael Graner, Kevin O. Lillehei, Randy L. Jensen, Anthony Fringuello, Tadeusz Wroblewski, David Ormond
Publikováno v:
30th Annual Meeting North American Skull Base Society.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62d730ff1fddfc666203845ae33be85a
https://doi.org/10.1055/s-0040-1702418
https://doi.org/10.1055/s-0040-1702418