Zobrazeno 1 - 10
of 509
pro vyhledávání: '"Michael Goggins"'
Autor:
Alison P. Klein, Brian M. Wolpin, Harvey A. Risch, Rachael Z. Stolzenberg-Solomon, Evelina Mocci, Mingfeng Zhang, Federico Canzian, Erica J. Childs, Jason W. Hoskins, Ashley Jermusyk, Jun Zhong, Fei Chen, Demetrius Albanes, Gabriella Andreotti, Alan A. Arslan, Ana Babic, William R. Bamlet, Laura Beane-Freeman, Sonja I. Berndt, Amanda Blackford, Michael Borges, Ayelet Borgida, Paige M. Bracci, Lauren Brais, Paul Brennan, Hermann Brenner, Bas Bueno-de-Mesquita, Julie Buring, Daniele Campa, Gabriele Capurso, Giulia Martina Cavestro, Kari G. Chaffee, Charles C. Chung, Sean Cleary, Michelle Cotterchio, Frederike Dijk, Eric J. Duell, Lenka Foretova, Charles Fuchs, Niccola Funel, Steven Gallinger, J. Michael M. Gaziano, Maria Gazouli, Graham G. Giles, Edward Giovannucci, Michael Goggins, Gary E. Goodman, Phyllis J. Goodman, Thilo Hackert, Christopher Haiman, Patricia Hartge, Manal Hasan, Peter Hegyi, Kathy J. Helzlsouer, Joseph Herman, Ivana Holcatova, Elizabeth A. Holly, Robert Hoover, Rayjean J. Hung, Eric J. Jacobs, Krzysztof Jamroziak, Vladimir Janout, Rudolf Kaaks, Kay-Tee Khaw, Eric A. Klein, Manolis Kogevinas, Charles Kooperberg, Matthew H. Kulke, Juozas Kupcinskas, Robert J. Kurtz, Daniel Laheru, Stefano Landi, Rita T. Lawlor, I.-Min Lee, Loic LeMarchand, Lingeng Lu, Núria Malats, Andrea Mambrini, Satu Mannisto, Roger L. Milne, Beatrice Mohelníková-Duchoňová, Rachel E. Neale, John P. Neoptolemos, Ann L. Oberg, Sara H. Olson, Irene Orlow, Claudio Pasquali, Alpa V. Patel, Ulrike Peters, Raffaele Pezzilli, Miquel Porta, Francisco X. Real, Nathaniel Rothman, Ghislaine Scelo, Howard D. Sesso, Gianluca Severi, Xiao-Ou Shu, Debra Silverman, Jill P. Smith, Pavel Soucek, Malin Sund, Renata Talar-Wojnarowska, Francesca Tavano, Mark D. Thornquist, Geoffrey S. Tobias, Stephen K. Van Den Eeden, Yogesh Vashist, Kala Visvanathan, Pavel Vodicka, Jean Wactawski-Wende, Zhaoming Wang, Nicolas Wentzensen, Emily White, Herbert Yu, Kai Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Peter Kraft, Donghui Li, Stephen Chanock, Ofure Obazee, Gloria M. Petersen, Laufey T. Amundadottir
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Genetic variants associated with susceptibility to pancreatic cancer have been identified using genome wide association studies (GWAS). Here, the authors combine data from over 9000 patients and perform a meta-analysis to identify five novel loci lin
Externí odkaz:
https://doaj.org/article/62f48b33d3e24b21a7c8f4e240a960a1
Autor:
Tushar D Bhagat, Dagny Von Ahrens, Meelad Dawlaty, Yiyu Zou, Joelle Baddour, Abhinav Achreja, Hongyun Zhao, Lifeng Yang, Brijesh Patel, Changsoo Kwak, Gaurav S Choudhary, Shanisha Gordon-Mitchell, Srinivas Aluri, Sanchari Bhattacharyya, Srabani Sahu, Prafulla Bhagat, Yiting Yu, Matthias Bartenstein, Orsi Giricz, Masako Suzuki, Davendra Sohal, Sonal Gupta, Paola A Guerrero, Surinder Batra, Michael Goggins, Ulrich Steidl, John Greally, Beamon Agarwal, Kith Pradhan, Debabrata Banerjee, Deepak Nagrath, Anirban Maitra, Amit Verma
Publikováno v:
eLife, Vol 8 (2019)
Even though pancreatic ductal adenocarcinoma (PDAC) is associated with fibrotic stroma, the molecular pathways regulating the formation of cancer associated fibroblasts (CAFs) are not well elucidated. An epigenomic analysis of patient-derived and de-
Externí odkaz:
https://doaj.org/article/de3a332d705e4701ab12d60c3c437380
Autor:
Marco Dal Molin, Aaron Brant, Amanda L Blackford, James F Griffin, Koji Shindo, Thomas Barkley, Neda Rezaee, Ralph H Hruban, Christopher L Wolfgang, Michael Goggins
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164195 (2016)
Prospective studies have identified obstructive sleep apnea (OSA) as a risk factor for increased overall cancer incidence and mortality. The potential role of OSA in the risk or progression of specific cancers is not well known. We hypothesized that
Externí odkaz:
https://doaj.org/article/1200eae2cd2d43308f0afc4953bf6af7
Autor:
Hannah Arem, Kai Yu, Xiaoqin Xiong, Kristin Moy, Neal D Freedman, Susan T Mayne, Demetrius Albanes, Alan A Arslan, Melissa Austin, William R Bamlet, Laura Beane-Freeman, Paige Bracci, Federico Canzian, Michelle Cotterchio, Eric J Duell, Steve Gallinger, Graham G Giles, Michael Goggins, Phyllis J Goodman, Patricia Hartge, Manal Hassan, Kathy Helzlsouer, Brian Henderson, Elizabeth A Holly, Robert Hoover, Eric J Jacobs, Aruna Kamineni, Alison Klein, Eric Klein, Laurence N Kolonel, Donghui Li, Núria Malats, Satu Männistö, Marjorie L McCullough, Sara H Olson, Irene Orlow, Ulrike Peters, Gloria M Petersen, Miquel Porta, Gianluca Severi, Xiao-Ou Shu, Kala Visvanathan, Emily White, Herbert Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Geoffrey S Tobias, Dennis Maeder, Michelle Brotzman, Harvey Risch, Joshua N Sampson, Rachael Z Stolzenberg-Solomon
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0117574 (2015)
Evidence on the association between vitamin D status and pancreatic cancer risk is inconsistent. This inconsistency may be partially attributable to variation in vitamin D regulating genes. We selected 11 vitamin D-related genes (GC, DHCR7, CYP2R1, V
Externí odkaz:
https://doaj.org/article/4780aef1d7f5435182461f1e11d75b6e
Autor:
Hannah Arem, Kai Yu, Xiaoqin Xiong, Kristin Moy, Neal D Freedman, Susan T Mayne, Demetrius Albanes, Laufey T Amundadottir, Alan A Arslan, Melissa Austin, William R Bamlet, Laura Beane-Freeman, Paige Bracci, Federico Canzian, Stephen J Chanock, Michelle Cotterchio, Eric J Duell, Steve Gallinger, Graham G Giles, Michael Goggins, Phyllis J Goodman, Patricia Hartge, Manal Hassan, Kathy Helzlsouer, Brian Henderson, Elizabeth A Holly, Robert Hoover, Eric J Jacobs, Aruna Kamineni, Alison Klein, Eric Klein, Laurence N Kolonel, Donghui Li, Núria Malats, Satu Männistö, Marjorie L McCullough, Sara H Olson, Irene Orlow, Ulrike Peters, Gloria M Petersen, Miquel Porta, Gianluca Severi, Xiao-Ou Shu, Stephen Van Den Eeden, Kala Visvanathan, Emily White, Herbert Yu, Anne Zeleniuch-Jacquotte, Wei Zheng, Geoffrey S Tobias, Dennis Maeder, Michelle Brotzman, Harvey Risch, Joshua N Sampson, Rachael Z Stolzenberg-Solomon
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129983 (2015)
Externí odkaz:
https://doaj.org/article/aa4f3f44a7a54110af0352048a79f630
Autor:
Alison P Klein, Sara Lindström, Julie B Mendelsohn, Emily Steplowski, Alan A Arslan, H Bas Bueno-de-Mesquita, Charles S Fuchs, Steven Gallinger, Myron Gross, Kathy Helzlsouer, Elizabeth A Holly, Eric J Jacobs, Andrea Lacroix, Donghui Li, Margaret T Mandelson, Sara H Olson, Gloria M Petersen, Harvey A Risch, Rachael Z Stolzenberg-Solomon, Wei Zheng, Laufey Amundadottir, Demetrius Albanes, Naomi E Allen, William R Bamlet, Marie-Christine Boutron-Ruault, Julie E Buring, Paige M Bracci, Federico Canzian, Sandra Clipp, Michelle Cotterchio, Eric J Duell, Joanne Elena, J Michael Gaziano, Edward L Giovannucci, Michael Goggins, Göran Hallmans, Manal Hassan, Amy Hutchinson, David J Hunter, Charles Kooperberg, Robert C Kurtz, Simin Liu, Kim Overvad, Domenico Palli, Alpa V Patel, Kari G Rabe, Xiao-Ou Shu, Nadia Slimani, Geoffrey S Tobias, Dimitrios Trichopoulos, Stephen K Van Den Eeden, Paolo Vineis, Jarmo Virtamo, Jean Wactawski-Wende, Brian M Wolpin, Herbert Yu, Kai Yu, Anne Zeleniuch-Jacquotte, Stephen J Chanock, Robert N Hoover, Patricia Hartge, Peter Kraft
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e72311 (2013)
We developed an absolute risk model to identify individuals in the general population at elevated risk of pancreatic cancer.Using data on 3,349 cases and 3,654 controls from the PanScan Consortium, we developed a relative risk model for men and women
Externí odkaz:
https://doaj.org/article/df004024296a457dbf8a9b710f783b2e
Autor:
Jun Yu, Kimberly Walter, Noriyuki Omura, Seung-Mo Hong, Angela Young, Ang Li, Audrey Vincent, Michael Goggins
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e43456 (2012)
Cancer associated stromal fibroblasts (CAFs) undergo transcriptional and phenotypic changes that contribute to tumor progression, but the mechanisms responsible for these changes are not well understood. Aberrant DNA methylation is an important cause
Externí odkaz:
https://doaj.org/article/12f08b329ca045de8261b1904c779c87
Autor:
Helena, Saba, Michael, Goggins
Publikováno v:
Gastroenterology Clinics of North America. 51:561-575
Individuals at increased risk of developing pancreatic cancer, including those with a significant family history of the disease and those with pancreatic cancer susceptibility gene variants, can benefit from pancreas surveillance. Most pancreatic can
Autor:
Mohamad Dbouk, Bryson W. Katona, Randall E. Brand, Amitabh Chak, Sapna Syngal, James J. Farrell, Fay Kastrinos, Elena M. Stoffel, Marcia Irene Canto, Michael Goggins
Publikováno v:
Journal of Clinical Oncology. 41:1147-1149
Autor:
Alison P. Klein, Ralph H. Hruban, Bert Vogelstein, Kenneth W. Kinzler, Nickolas Papadopoulos, James R. Eshleman, Rachel Karchin, Michael Goggins, Peter P. Zandi, Laura D. Wood, Christopher L. Wolfgang, Yuxuan Wang, Alyssa L. Smith, Andrew D. Rhim, James B. Potash, Mehdi Pirooznia, Jennifer Parla, Noushin Niknafs, K. Wyatt McMahon, Richard W. McCombie, Alvin Makohon-Moore, Melissa Kramer, Christine Iacobuzio-Donahue, Joseph M. Herman, Fernando S. Goes, Christopher Douville, Erica J. Childs, Michele L. Cote, Yun-Ching Chen, Kari G. Chaffee, Jennifer Axilbund, Syed Z. Ali, George Zogopoulos, Sapna Syngal, Elena Stoffel, Ann G. Schwartz, Anil K. Rustgi, Sara H. Olson, Robert C. Kurtz, Steven Gallinger, Randall Brand, Melissa L. Bondy, Gloria M. Petersen, Alexis L. Norris, Nicholas J. Roberts
Supplementary Tables S1 - S12. Supplementary Table S1. Prioritization of candidate FPC susceptibility genes by private heterozygous PTVs. Supplementary Table S2. FPC patients harboring a private PTVs ASXL1, DNMT3A, and TET2. Supplementary Table S3. 8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::575bafdf79112f2f0bd50501c80d81de
https://doi.org/10.1158/2159-8290.22531232.v1
https://doi.org/10.1158/2159-8290.22531232.v1