Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Michael Girgis"'
Autor:
Esra Oktay, Farhang Alem, Keziah Hernandez, Michael Girgis, Christopher Green, Divita Mathur, Igor L. Medintz, Aarthi Narayanan, Remi Veneziano
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-11 (2023)
A DNA origami nanoparticle-based vaccine against SARS-Cov-2 co-delivers viral RBD antigen and CpG adjuvant and elicits a robust protective immunity against the virus in a mouse model.
Externí odkaz:
https://doaj.org/article/c458177b8dfe441594f04cc9f32b63aa
Autor:
Yaoxiang Li, Michael Girgis, Meth Jayatilake, Artur A. Serebrenik, Amrita K. Cheema, Michael D. Kaytor, Vijay K. Singh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract BIO 300, a pharmaceutical formulation of genistein, is being developed as a radiation countermeasure to treat hematopoietic acute radiation syndrome (H-ARS) and the delayed effects of acute radiation exposure (DEARE). Several studies have af
Externí odkaz:
https://doaj.org/article/1fd6a8a4d1f645938839e42b36f38314
Autor:
Charles P. Hinzman, Meth Jayatilake, Sunil Bansal, Brian L. Fish, Yaoxiang Li, Yubo Zhang, Shivani Bansal, Michael Girgis, Anton Iliuk, Xiao Xu, Jose A. Fernandez, John H. Griffin, Elizabeth A. Ballew, Keith Unger, Marjan Boerma, Meetha Medhora, Amrita K. Cheema
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-12 (2022)
Abstract Background Urinary extracellular vesicles (EVs) are a source of biomarkers with broad potential applications across clinical research, including monitoring radiation exposure. A key limitation to their implementation is minimal standardizati
Externí odkaz:
https://doaj.org/article/c5426affb3a14b0b9aa3b0ca913f86c2
Autor:
Congyi Lu, Akanksha Mahajan, Sung-Hyeok Hong, Susana Galli, Shiya Zhu, Jason U. Tilan, Nouran Abualsaud, Mina Adnani, Stacey Chung, Nada Elmansy, Jasmine Rodgers, Olga Rodriguez, Christopher Albanese, Hongkun Wang, Maureen Regan, Valerie Zgonc, Jan Blancato, Ewa Krawczyk, G. Ian Gallicano, Michael Girgis, Amrita Cheema, Ewa Iżycka-Świeszewska, Luciane R. Cavalli, Svetlana D. Pack, Joanna Kitlinska
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Ewing sarcoma tumour cells frequently metastasize to the bone but the molecular mechanisms governing this process are not well understood. Here, the authors show that neuropeptide Y/Y5 receptor pathway is activated in the hypoxic tumour microenvironm
Externí odkaz:
https://doaj.org/article/41f842ff92e247859c6f0dac0e31c7e6
Autor:
Amrita K. Cheema, Yaoxiang Li, Jatinder Singh, Ryan Johnson, Michael Girgis, Stephen Y. Wise, Oluseyi O. Fatanmi, Michael D. Kaytor, Vijay K. Singh
Publikováno v:
Animal Microbiome, Vol 3, Iss 1, Pp 1-12 (2021)
Abstract Background The mammalian gut harbors very complex and diverse microbiota that play an important role in intestinal homeostasis and host health. Exposure to radiation results in dysbiosis of the gut microbiota leading to detrimental pathophys
Externí odkaz:
https://doaj.org/article/ec2bcc200b554ba498d6888aa7bd186a
Autor:
Yaoxiang Li, Michael Girgis, Stephen Y. Wise, Oluseyi O. Fatanmi, Thomas M. Seed, Manoj Maniar, Amrita K. Cheema, Vijay K. Singh
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract To date, the United States Food and Drug Administration (FDA) has approved four drugs to mitigate hematopoietic acute radiation syndrome and all four are repurposed radiomitigators. There are several additional drug candidates currently unde
Externí odkaz:
https://doaj.org/article/80b88c81ca084e9ba1188c3b3a5941af
Autor:
Charles P. Hinzman, Baldev Singh, Shivani Bansal, Yaoxiang Li, Anton Iliuk, Michael Girgis, Kelly M. Herremans, Jose G. Trevino, Vijay K. Singh, Partha P. Banerjee, Amrita K. Cheema
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 6, Pp n/a-n/a (2022)
Abstract Although cancer‐derived extracellular vesicles (cEVs) are thought to play a pivotal role in promoting cancer progression events, their precise effect on neighbouring normal cells is unknown. In this study, we investigated the impact of pan
Externí odkaz:
https://doaj.org/article/9e319cf9e0cc4f0492d26f6df4076679
Autor:
Hisham Elnawam, Menatallah Abdelmougod, Ahmed Mobarak, Mai Hussein, Hamdy Aboualmakarem, Michael Girgis, Rania El Backly
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Regenerative endodontic procedures have been described for over a decade as a paradigm shift in the treatment of immature necrotic permanent teeth, owing to their ability to allow root maturation with subsequent enhancement of the tooth’s fracture
Externí odkaz:
https://doaj.org/article/9b5ccdc7c410456e8fa54ebd7c0429be
Autor:
Congyi Lu, Akanksha Mahajan, Sung-Hyeok Hong, Susana Galli, Shiya Zhu, Jason U. Tilan, Nouran Abualsaud, Mina Adnani, Stacey Chung, Nada Elmansy, Jasmine Rodgers, Olga Rodriguez, Christopher Albanese, Hongkun Wang, Maureen Regan, Valerie Zgonc, Jan Blancato, Ewa Krawczyk, G. Ian Gallicano, Michael Girgis, Amrita Cheema, Ewa Iżycka-Świeszewska, Luciane R. Cavalli, Svetlana D. Pack, Joanna Kitlinska
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/1bdaaeb070454c56981e47dbacb258f6
Autor:
Amrita K. Cheema, Yaoxiang Li, Michael Girgis, Meth Jayatilake, Oluseyi O. Fatanmi, Stephen Y. Wise, Thomas M. Seed, Vijay K. Singh
Publikováno v:
Metabolites, Vol 10, Iss 5, p 211 (2020)
Acute exposure to high-dose ionizing irradiation has the potential to severely injure the hematopoietic system and its capacity to produce vital blood cells that innately serve to ward off infections and excessive bleeding. Developing a medical radia
Externí odkaz:
https://doaj.org/article/5a9fdfffcdac4a538534f02e35566db0