Variability in Intracranial Vessel Diameters and Considerations for Neurovascular Models: A Systematic Review and Meta‐Analysis

Autor: Mahmood Mirza, Katie Kummer, Jillienne Touchette, Ray McCarthy, Ansaar Rai, Patrick Brouwer, Michael Gilvarry

Publikováno v: Stroke: Vascular and Interventional Neurology, Vol 4, Iss 4 (2024)

Background In vitro experiments are critical for understanding the impact of medical devices and techniques on blood vessels and blood flow. However, their interpretation is often limited by anatomical models’ inability to capture the wide range of

Externí odkaz: https://doaj.org/article/dac767b6a3434cc4b82fb176255df170

A Review of the Advancements in the in-vitro Modelling of Acute Ischemic Stroke and Its Treatment

Autor: Sarah Johnson, Anushree Dwivedi, Mahmood Mirza, Ray McCarthy, Michael Gilvarry

Publikováno v: Frontiers in Medical Technology, Vol 4 (2022)

In-vitro neurovascular models of large vessel occlusions (LVOs) causing acute ischemic stroke (AIS) are used extensively for pre-clinical testing of new treatment devices. They enable physicians and engineers to examine device performance and the res

Externí odkaz: https://doaj.org/article/f06f741f3c124e838638969513412681

Orbit image analysis machine learning software can be used for the histological quantification of acute ischemic stroke blood clots.

Autor: Seán Fitzgerald, Shunli Wang, Daying Dai, Dennis H Murphree, Abhay Pandit, Andrew Douglas, Asim Rizvi, Ramanathan Kadirvel, Michael Gilvarry, Ray McCarthy, Manuel Stritt, Matthew J Gounis, Waleed Brinjikji, David F Kallmes, Karen M Doyle

Publikováno v: PLoS ONE, Vol 14, Iss 12, p e0225841 (2019)

Our aim was to assess the utility of a novel machine learning software (Orbit Image Analysis) in the histological quantification of acute ischemic stroke (AIS) clots. We analyzed 50 AIS blood clots retrieved using mechanical thrombectomy procedures.

Externí odkaz: https://doaj.org/article/4a0cf10fd7234cfbbf1165ef64176f27

Does prior administration of rtPA influence acute ischemic stroke clot composition? Findings from the analysis of clots retrieved with mechanical thrombectomy from the RESTORE registry

Autor: Alan O'Hare, Sara Molina, Jeanette Carlqvist, Klearchos Psychogios, Dennis Dunker, Ágnes Vadász, Georgios Magoufis, Annika Nordanstig, Seán Fitzgerald, Ray McCarthy, Karen M. Doyle, Michael Gilvarry, Rosanna Rossi, Ciara Tierney, Katarina Jood, Alexandros Rentzos, John Thornton, István Szikora, Erik Ceder, Andrew Douglas, Petra Redfors, Sarah Power, Turgut Tatlisumak, Paul Brennan, Abhay Pandit, András Nagy, Oana Madalina Mereuta, Georgios Tsivgoulis

Publikováno v: Journal of Neurology. 269:1913-1920

Background and purpose There is still much debate whether bridging-therapy [intravenous thrombolysis (IVT) prior to mechanical thrombectomy (MT)] might be beneficial compared to MT alone. We investigated the effect of IVT on size and histological com

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b3f747b214d54f7cb806f1ad2b9d412
https://doi.org/10.1007/s00415-021-10758-5

Quantitative 3D analysis of tissue damage in a rat model of microembolization

Autor: Anushree Dwivedi, Francesco Migliavacca, Simon F. De Meyer, Nerea Arrarte Terreros, Vanessa Blanc-Guillemaud, Stephen J. Payne, Ed van Bavel, Sarah Vandelanotte, Tamás I. Józsa, Ray McCarthy, Praneeta R Konduri, Gabriele Dubini, Jose Felix Rodriguez Matas, Aad van der Lugt, H.F. Lingsma, Diederik W.J. Dippel, Raymond M. Padmos, Ybwem (Yvo) Roos, Bastien Chopard, Henk A. Marquering, Ed VanBavel, A. M. Shibeko, Giulia Luraghi, Patrick Mc Garry, Mikhail A. Panteleev, Sissy Georgakopoulou, Sara Bridio, Kevin M. Moerman, Sharon Duffy, Michael Gilvarry, Charles B. L. M. Majoie, Victor Azizi, Noor Samuels, Franck Raynaud, Nikki Boodt, Remy Petkantchin, Senna Staessens, Theodosia Georgakopoulou, Claire Miller, Karim Zouaoui Boudjeltia, Max van der Kolk, Behrooz Fereidoonnezhad, Erik N. T. P. Bakker, Alfons G. Hoekstra, Anne Eva van der Wijk

Publikováno v: Journal of biomechanics, 128:110723. Elsevier Limited
Journal of Biomechanics, 128:110723. Elsevier Ltd.
Journal of Biomechanics, 128:110723. Elsevier
Journal of Biomechanics, 128:110723. Elsevier Limited
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There is a discrepancy between successful recanalization and good clinical outcome after endovascular treatment (EVT) in acute ischemic stroke patients. During removal of a thrombus, a shower of microemboli may release and lodge to the distal circula

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb0da97e38e7e5b511ea60b581bbb48
https://pure.amc.nl/en/publications/quantitative-3d-analysis-of-tissue-damage-in-a-rat-model-of-microembolization(ed81f25c-d747-4f7c-af72-e57e02b9d863).html