Zobrazeno 1 - 10 of 14 pro vyhledávání: '"Michael Gilman"'
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Abstract A220: Destabilizing domain technology facilitates exogenous regulation of IL15 and IL12 for adaptive T-cell therapy
Autor: Michael Gilman, Tucker Ezell, Michelle Ols, Vipin Suri, Tariq A. Kassum, Kutlu G. Elpek, Abhishek Kulkarni, Grace Y. Olinger, Heller Scott Francis, Dan Jun Li, Celeste Richardson, Dexue Sun, Steven M. Shamah, Mara Christine Inniss, Karen Tran, Michael Briskin, Christopher Reardon
Publikováno v: Cancer Immunology Research. 7:A220-A220
Cytokines are messenger molecules that act as regulators of innate and adaptive immunity by propagating cell-cell immune signaling. Several cytokines have been approved for the treatment of metastatic renal cell cancer, advanced melanoma, and hairy c
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65f8e2ab480a5f13138fab5da3d90ba2
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-a220
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2
Use of Subtidal Habitat by the Asian Shore CrabHemigrapsus sanguineusin Long Island Sound
Autor: Michael Gilman, Sean P. Grace
Publikováno v: Northeastern Naturalist. 16:481-487
Hemigrapsus sanguineus Asian Shore Crab is an introduced but now common crab found intertidally along the Connecticut coastline. Little is known of its subtidal occurrence. This species was found to be seasonally abundant subtidally, at depths varyin
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::308240b0862dbd821fc12a9abef96015
https://doi.org/10.1656/045.016.n314
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3
Regulated Delivery of Therapeutic Proteins After in Vivo Somatic Cell Gene Transfer
Autor: Joseph V. Hughes, James M. Wilson, Franklin Cerasoli, Philip W. Zoltick, Victor M. Rivera, Guangping Gao, Michael Gilman, Xuehai Ye, Michael A. Schnell
Publikováno v: Science. 283:88-91
Stable delivery of a therapeutic protein under pharmacologic control was achieved through in vivo somatic gene transfer. This system was based on the expression of two chimeric, human-derived proteins that were reconstituted by rapamycin into a trans
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::360460340bfd71151db3b2fa302bd9ef
https://doi.org/10.1126/science.283.5398.88
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5
Pharmacologic control of a humanized gene therapy system implanted into nude mice
Autor: Victor M. Rivera, Shannon R. Magari, John Iuliucci, Franklin Cerasoli, Michael Gilman
Systemic delivery of specific therapeutic proteins by a parenteral route of administration is a recognized practice in the management of several gene defects and acquired diseases. As an alternative to repetitive parenteral administration, gene thera
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3616731e48a869e9a769f7d08ef2f10c
https://europepmc.org/articles/PMC508493/
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6
Protein and DNA contact surfaces that mediate the selective action of the Phox1 homeodomain at the c-fos serum response element
Autor: Dorre A. Grueneberg, Michael Gilman, Kenneth Simon
Publikováno v: Molecular and cellular biology. 17(11)
The human homeodomain protein Phox1 can impart serum-responsive transcriptional activity to the c-fos serum response element (SRE) by interacting with serum response factor (SRF). This activity is shared with other Paired class homeodomains but not w
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a4791b0e1dc440038016f058c60e629
https://pubmed.ncbi.nlm.nih.gov/9343429
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7
Transcriptional squelching re-examined
Autor: Elizabeth Molinari, Sridaran Natesan, Victor M. Rivera, Michael Gilman
Publikováno v: Nature. 390:349-350
The introduction of a potent transcriptional activator into eukaryotic cells can paradoxically suppress the transcription of a co-introduced target gene1,2,3. This so-called ‘squelching’ is thought to result from titration of one or more general
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ab373f2c51244af8d52e1642db6f1b8
https://doi.org/10.1038/37019
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8
OSTEOSARCOMA IN THE MIDDIAPHYSIS OF THE RADIUS IN THE DOG
Autor: Michael Gilman, Bruce D. Car, Victor T. Rendano
Publikováno v: Veterinary Radiology. 28:127-130
This case report describes the radiographic/clinical progression of a lesion in the middiaphysis of the radius in a dog. The lesion initially looked benign but progressed and eventually was diagnosed as an anaplastic osteosarcoma.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::bcf2cecc0aff6893711134b6a7c20262
https://doi.org/10.1111/j.1740-8261.1987.tb00039.x
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9
Colorimetric determination of ligands by the effect of their cobalt(II) complexes on redox indicators
Autor: Michael D. Sulkin, Arnold M. Seligman, Michael Gilman, Jacob S. Hanker
Publikováno v: Analytica Chimica Acta. 28:150-155
Coordination of cobalt(II) with ligands facilitates oxidation to the trivalent state by an oxidizing agent such as 3- p -iodophenyl-2- p -nitrophenyl tetrazolium chloride (INT). Since the formazan produced by the reduction of the tetrazolium chloride
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a23294fed708c14c9e956c6851a13e54
https://doi.org/10.1016/s0003-2670(00)87212-8
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