Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michael Germuska"'
Autor:
Louise Terry, Kevin Murphy, Jessica J Steventon, Miguel O Bernabeu, Melissa E Wright, Andrew Crofts, Saajan Davies, Hannah Chandler, Ian Driver, Michael Germuska, Ylenia Giarratano
Publikováno v:
BMJ Open Ophthalmology, Vol 9, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/3701c58280b24c628db1055f77f8d489
Autor:
Emma Biondetti, Antonio Maria Chiarelli, Michael Germuska, Ilona Lipp, Alessandro Villani, Alessandra S. Caporale, Eleonora Patitucci, Kevin Murphy, Valentina Tomassini, Richard G. Wise
Publikováno v:
NeuroImage, Vol 285, Iss , Pp 120492- (2024)
BOLD fMRI signal has been used in conjunction with vasodilatory stimulation as a marker of cerebrovascular reactivity (CVR): the relative change in cerebral blood flow (CBF) arising from a unit change in the vasodilatory stimulus. Using numerical sim
Externí odkaz:
https://doaj.org/article/e6e16814e70f4f7a8e5ec4e3dc15dc5c
Autor:
Michael Germuska, Hannah Louise Chandler, Thomas Okell, Fabrizio Fasano, Valentina Tomassini, Kevin Murphy, Richard G. Wise
Publikováno v:
Frontiers in Artificial Intelligence, Vol 4 (2021)
Externí odkaz:
https://doaj.org/article/6c9616919b634ecfa731fa99eb4ebf53
Autor:
Michael Germuska, Hannah Louise Chandler, Thomas Okell, Fabrizio Fasano, Valentina Tomassini, Kevin Murphy, Richard G. Wise
Publikováno v:
Frontiers in Artificial Intelligence, Vol 3 (2020)
Magnetic resonance imaging (MRI) offers the possibility to non-invasively map the brain's metabolic oxygen consumption (CMRO2), which is essential for understanding and monitoring neural function in both health and disease. However, in depth study of
Externí odkaz:
https://doaj.org/article/b837f760be23499d88cbc504fb8a6dac
Autor:
Antonio M, Chiarelli, Michael, Germuska, Hannah, Chandler, Rachael, Stickland, Eleonora, Patitucci, Emma, Biondetti, Daniele, Mascali, Neeraj, Saxena, Sharmila, Khot, Jessica, Steventon, Catherine, Foster, Ana E, Rodríguez-Soto, Erin, Englund, Kevin, Murphy, Valentina, Tomassini, Felix W, Wehrli, Richard G, Wise
Publikováno v:
J Cereb Blood Flow Metab
One promising approach for mapping CMRO(2) is dual-calibrated functional MRI (dc-fMRI). This method exploits the Fick Principle to combine estimates of CBF from ASL, and OEF derived from BOLD-ASL measurements during arterial O(2) and CO(2) modulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::076cab2f46b03bca9491f567e5dd06ea
https://pubmed.ncbi.nlm.nih.gov/35107026
https://pubmed.ncbi.nlm.nih.gov/35107026
Autor:
Catherine Foster, T. Massey, Richard G. Wise, H. Dingsdale, Michael Germuska, Hannah L. Chandler, Kevin Murphy, Jessica J Steventon, G. Parker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
Exercise is beneficial for brain health, inducing neuroplasticity and vascular plasticity in the hippocampus, which is possibly mediated by brain-derived neurotrophic factor (BDNF) levels. Here we investigated the short-term effects of exercise, to d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::660a6c41c220d418838d5d82871cc483
https://doaj.org/article/47808eb419c14e0fa8b9c6a8cb36d45e
https://doaj.org/article/47808eb419c14e0fa8b9c6a8cb36d45e
Autor:
Hannah L Chandler, Rachael C Stickland, Eleonora Patitucci, Michael Germuska, Antonio M Chiarelli, Catherine Foster, Shona Bhome-Dhaliwal, Thomas M Lancaster, Neeraj Saxena, Sharmila Khot, Valentina Tomassini, Richard G Wise
Publikováno v:
Cardiff University
Cerebral energy deficiency is increasingly recognised as an important feature of multiple sclerosis (MS). Until now, we have lacked non-invasive imaging methods to quantify energy utilisation and mitochondrial function in the human brain. Here, we us
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb7a1baef139e904e05b222dc78e465c
https://pubmed.ncbi.nlm.nih.gov/36071645
https://pubmed.ncbi.nlm.nih.gov/36071645
Autor:
Antonio M Chiarelli, Michael Germuska, Hannah Chandler, Rachael Stickland, Eleonora Patitucci, Emma Biondetti, Daniele Mascali, Neeraj Saxena, Sharmila Khot, Jessica Steventon, Catherine Foster, Ana E Rodríguez-Soto, Erin Englund, Kevin Murphy, Valentina Tomassini, Felix W Wehrli, Richard G Wise
One promising approach for mapping CMRO2 is dual-calibrated functional MRI (dc-fMRI). This method exploits the Fick Principle to combine estimates of CBF from ASL, and OEF derived from BOLD-ASL measurements during arterial O2 and CO2 modulations. Mul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9efb137e9899339e8c351189c094b2d
Autor:
Richard G. Wise, Rachael C. Stickland, Michael Germuska, Antonio Maria Chiarelli, Hannah L. Chandler
Magnetic resonance imaging (MRI) offers the possibility to non-invasively map the rate of cerebral metabolic oxygen consumption (CMRO2), which is essential for understanding and monitoring neural function in both health and disease. Existing methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f2acc5fdb27de62455b4dd94c23e6485
https://doi.org/10.1101/2021.04.08.438939
https://doi.org/10.1101/2021.04.08.438939
Autor:
Thomas M. Lancaster, Rachael C. Stickland, Hannah L. Chandler, Neeraj Saxena, Sharmila Khot, Shona Bhome-Dhaliwal, Catherine Foster, Richard G. Wise, Valentina Tomassini, Michael Germuska, Eleonora Patitucci
Evidence suggests that cerebrovascular function and oxygen consumption are altered in multiple sclerosis (MS). Here, we quantified the vascular and oxygen metabolic MRI burden in patients with MS (PwMS) and assessed the relationship between these MRI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c49b87d48b62ba596a91b8f4406c17a4
https://doi.org/10.1101/2021.01.07.425819
https://doi.org/10.1101/2021.01.07.425819