Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Michael G. Paine"'
Autor:
Michael G. Paine, Marie W. Wooten
Publikováno v:
Impulse: The Premier Undergraduate Neuroscience Journal, p 1 (2006)
The ubiquitin-proteasome system (UPS) is the pathway for degradation of nuclear and cytosolic proteins that are aged, damaged, or misfolded. Malfunctions in the UPS have been implicated in a wide variety of neurodegenerative diseases. Some proteins,
Externí odkaz:
https://doaj.org/article/aa2ce476b76f45c8a7f95e2054d9c7b4
Publikováno v:
Resuscitation. 83:1511-1516
The cerebellum is among the brain regions most vulnerable to damage caused by cardiac arrest, and cerebellar Purkinje cell loss may contribute to neurologic dysfunction, including post-hypoxic myoclonus. However, it remains unknown whether cerebellar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92e57b1928528e41b97ffb2555edfed
https://doi.org/10.1016/j.resuscitation.2012.05.022
https://doi.org/10.1016/j.resuscitation.2012.05.022
Autor:
Michael C. Wooten, Thangiah Geetha, Marie W. Wooten, Xiao Hu, M. Lamar Seibenhener, J. Ramesh Babu, Michael G. Paine
Publikováno v:
Journal of Biomedicine and Biotechnology, Vol 2006 (2006)
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology
Aggregated misfolded proteins are hallmarks of most neurodegenerative diseases. In a chronic disease state, including pathologic situations of oxidative stress, these proteins are sequestered into inclusions. Accumulation of aggregated proteins can b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45260168a5b238a0a814e514b054433b
https://doi.org/10.1155/jbb/2006/62079
https://doi.org/10.1155/jbb/2006/62079
Publikováno v:
FEBS Letters. 579:5029-5034
The polyubiquitin-binding protein p62 has been shown to localize in aggregates common to several types of diseases. Here, we report that p62 forms independent fibrillar aggregates in vitro in a time- and concentration-dependent manner. FTIR spectra a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9acb8cd1adab06d629494e8a38c55b2
https://doi.org/10.1016/j.febslet.2005.08.010
https://doi.org/10.1016/j.febslet.2005.08.010