Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Michael G. McCoy"'
Autor:
David A. Gross, Henry S. Cheng, Rulin Zhuang, Michael G. McCoy, Daniel Pérez-Cremades, Zachary Salyers, A.K.M. Khyrul Wara, Stefan Haemmig, Terence E. Ryan, Mark W. Feinberg
Publikováno v:
JCI Insight, Vol 7, Iss 1 (2022)
SNHG12, a long noncoding RNA (lncRNA) dysregulated in atherosclerosis, is known to be a key regulator of vascular senescence in endothelial cells (ECs). However, its role in angiogenesis and peripheral artery disease has not been elucidated. Hind-lim
Externí odkaz:
https://doaj.org/article/2959e62ce2ee4472a7e604a09902ea61
Autor:
Michael G. McCoy, Anurag Jamaiyar, Grasiele Sausen, Henry S. Cheng, Daniel Pérez-Cremades, Rulin Zhuang, Jingshu Chen, Philip P. Goodney, Mark A. Creager, Marc S. Sabatine, Marc P. Bonaca, Mark W. Feinberg
Publikováno v:
Angiogenesis. 26:107-127
Autor:
Haoyang Zhou, Dafeng Yang, Henry S. Cheng, Michael G. McCoy, Daniel Pérez‐Cremades, Stefan Haemmig, Danny Wong, Lei Chen, Mark W. Feinberg
Publikováno v:
FASEB J
Endothelial cell (EC) aging plays a vital role in the pathogenesis of cardiovascular disease (CVD). MicroRNAs have emerged as crucial regulators of target gene expression by inhibiting mRNA translation and/or promoting mRNA degradation. We identify a
Autor:
Michael G. McCoy, Daniel Pérez‐Cremades, Nathan Belkin, Wenhui Peng, Bofang Zhang, Jingshu Chen, Madhur Sachan, A. K. M. Khyrul Wara, Rulin Zhuang, Henry S. Cheng, Mark W. Feinberg
Publikováno v:
The FASEB Journal. 36
Cellular reprogramming through targeting microRNAs (miRNAs) holds promise for regenerative therapy due to their profound regulatory effects in proliferation, differentiation, and function. We hypothesized that transdifferentiation of vascular smooth
Autor:
Svyatoslav Tkachenko, Tatiana V. Byzova, Eugene A. Podrez, Detao Gao, Michael G. McCoy, Daniel W. Nascimento, Rakhylia Murtazina, Manoj Veleeparambil
Publikováno v:
Sci Signal
Toll-like receptor 2 (TLR2) is implicated in various pathologies, mainly in terms of its function within innate immune cells. However, TLR2 is also present in endothelial cells. Here, we explored the physiological and pathophysiological roles of endo
Autor:
Michael G McCoy, Terence E. Ryan, A.K.M. Khyrul Wara, Stefan Haemmig, Mark W. Feinberg, Rulin Zhuang, Daniel Pérez-Cremades, David A. Gross, Zachary R. Salyers, Henry S. Cheng
Publikováno v:
JCI Insight
SNHG12, a long non-coding RNA (lncRNA) dysregulated in atherosclerosis, is known to be a key regulator of vascular senescence in endothelial cells (ECs). However, its role in angiogenesis and peripheral artery disease (PAD) has not been elucidated. H
Autor:
Dennis Nyanyo, Julian Palacios Goerger, Michael G. McCoy, Claudia Fischbach, Carol K. Hung, Rebecca M. Williams, Warren R. Zipfel, Nozomi Nishimura
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-14 (2019)
Rapid growth and perivascular invasion are hallmarks of glioblastoma (GBM) that have been attributed to the presence of cancer stem-like cells (CSCs) and their association with the perivascular niche. However, the mechanisms by which the perivascular
Publikováno v:
Acta Biomaterialia. 44:200-208
Neovascularization is a hallmark of physiological and pathological tissue remodeling that is regulated in part by the extracellular matrix (ECM). Collagen I hydrogels or Matrigel are frequently used to study vascular network formation; however, in is
Publikováno v:
Journal of Materials Science: Materials in Medicine. 23:1645-1654
Collagen and hyaluronic acid (HA) are main components of the extracellular matrix and have been utilized in electrospinning; a technique that creates nanosized fibers for tissue scaffolds. A collagen/HA polymer solution was electrospun into a scaffol
Publikováno v:
Computer Physics Communications. 43:69-87
Over the past decade we have witnessed an evolution of scientific computers in which more and more concurrent or parallel arithmetic operations are allowed. The segmented pipeline arithmetic functional units, direct vectorization, indirect vectorizat