Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Michael G. Löffler"'
Autor:
Jonathan P. Belman, Estifanos N. Habtemichael, Abel R. Alcázar-Román, Varman T. Samuel, Hongjie Li, Jonathan S. Bogan, Bradley R. Rubin, Nai-Wen Chi, Michael G. Löffler, Omar Julca, Laura R. Grossi
Publikováno v:
Journal of Biological Chemistry. 290:14454-14461
In adipose and muscle cells, insulin stimulates the exocytic translocation of vesicles containing GLUT4, a glucose transporter, and insulin-regulated aminopeptidase (IRAP), a transmembrane aminopeptidase. A substrate of IRAP is vasopressin, which con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::683e1ecb93b71e8d83b6f960e357b613
https://doi.org/10.1074/jbc.c115.639203
https://doi.org/10.1074/jbc.c115.639203
Autor:
James Cresswell, Leah McNally, Michael G. Löffler, Chenfei Yu, Mingming Hao, Bradley R. Rubin, Jonathan S. Bogan, Jonathan P. Belman, Charisse M Orme
Publikováno v:
Journal of Biological Chemistry. 287:23932-23947
To promote glucose uptake into fat and muscle cells, insulin causes the translocation of GLUT4 glucose transporters from intracellular vesicles to the cell surface. Previous data support a model in which TUG traps GLUT4-containing vesicles and tether
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06151c2d42d60748bcdf01b2be322d3c
https://doi.org/10.1074/jbc.m112.339457
https://doi.org/10.1074/jbc.m112.339457
Autor:
Dongyan Zhang, Brett P. Monia, Yoshio Nagai, James Cresswell, Michael G. Löffler, Derek M. Erion, Xing-Xian Yu, Jonathan S. Bogan, Shin Yonemitsu, Takanori Iwasaki, Michael J. Jurczak, Varman T. Samuel, Sanjay Bhanot, Dirk Weismann, Jianying Dong, Romana Stark, Susan F. Murray, Gerald I. Shulman
Publikováno v:
Cell Metabolism. 9(3):252-264
Peroxisome proliferator-activated receptor gamma coactivator-1 beta (PGC-1beta) is known to be a transcriptional coactivator for SREBP-1, the master regulator of hepatic lipogenesis. Here, we evaluated the role of PGC-1beta in the pathogenesis of fru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd3d4aaba15f990314fdef6e10dd3e98
Publikováno v:
Journal of Biological Chemistry. 282:7710-7722
Insulin stimulates glucose uptake in fat and muscle by redistributing GLUT4 glucose transporters from intracellular membranes to the cell surface. We previously proposed that, in 3T3-L1 adipocytes, TUG retains GLUT4 within unstimulated cells and insu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::849108a700d6b21a906239adb0ef0540
https://doi.org/10.1074/jbc.m610824200
https://doi.org/10.1074/jbc.m610824200
Autor:
Gregory D. Cartee, Hui-Young Lee, Michael G. Löffler, Brandon M. Gassaway, William M. Philbrick, Varman T. Samuel, Andreas L. Birkenfeld, Gerald I. Shulman, Katerina M. Philbrick, Carmen J. Booth, François R Jornayvaz, Estifanos N. Habtemichael, Carlos M. Castorena, Jonathan S. Bogan, Cheol Soo Choi, Jonathan P. Belman
Publikováno v:
Journal of Biological Chemistry, Vol. 288, No 28 (2013) pp. 20135-50
Insulin stimulates glucose uptake in 3T3-L1 adipocytes in part by causing endoproteolytic cleavage of TUG (tether containing a ubiquitin regulatory X (UBX) domain for glucose transporter 4 (GLUT4)). Cleavage liberates intracellularly sequestered GLUT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6756aa26a7c75b7d1a9a2fefcd480c6
https://europepmc.org/articles/PMC3711282/
https://europepmc.org/articles/PMC3711282/
