Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Michael G. Hogg"'
Autor:
Paul C. De Marco, Roman M. Salasznyk, Sylvain Antoniotti, Lakshmi Kamath, Jonathan S. Dordick, Disha Ahuja, George E. Plopper, Robert F. Klees, Michael G. Hogg
Publikováno v:
Journal of Biomedicine and Biotechnology, Vol 2006 (2006)
Journal of Biomedicine and Biotechnology
Journal of Biomedicine and Biotechnology
Cancer cells are defined by their ability to divide uncontrollably and metastasize to secondary sites in the body. Consequently, tumor cell migration represents a promising target for anticancer drug development. Using our high-throughput cell migrat
Autor:
Fauod Ishmael, David M. Kwait, Michael G. Hogg, James A. Holland, Linda M. Ziegler, Chambers V. Hughes, Kurt J. Schillinger, Jonathan S. Dordick, David K. Johnson, Ming-Mei Chang, Lakshmi Santhanam, Robert O'Donnell, Erin J. McNamara
Publikováno v:
Endothelium. 9:191-203
NADPH oxidase is a major enzymatic source of oxygen free radicals in stimulated endothelial cells (ECs). The ortho-methoxy-substituted catechol, apocynin (4-hydroxy-3-methoxyacetophenone), isolated from the traditional medicinal plant Picrorhiza kurr
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 8(13)
A method for high-throughput retroviral transfection of genes and interfering RNA into 3D cell-culture microarrays is described. 3D cultures more closely mimic the in vivo cellular milieu, thus providing cellular responses to genetic manipulation mor
Publikováno v:
ACS nano. 4(8)
Three-dimensional (3D) cellular assays closely mimic the in vivo milieu, providing a rapid, inexpensive system for screening drug candidates for toxicity or efficacy in the early stages of drug discovery. However, 3D culture systems may suffer from m
Autor:
R. Anand Kumar, Sumitra M. Sukumaran, Michael G. Hogg, Douglas S. Clark, Moo-Yeal Lee, Jonathan S. Dordick
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 105(1)
We have developed a miniaturized 3D cell-culture array (the Data Analysis Toxicology Assay Chip or DataChip) for high-throughput toxicity screening of drug candidates and their cytochrome P450-generated metabolites. The DataChip consists of human cel
Publikováno v:
Organic letters. 6(12)
[reaction: see text] The biocatalytic oxidation of o-methoxyphenolic compounds led to a variety of oligophenols (dimers to pentamers) and some of their oxidation products. The reaction was carried out in an aqueous medium at room temperature with hyd
Autor:
Ivar Giaever, Charles R. Keese, Hwai Shi Wang, Ray C. Henrikson, Terry J. Smith, Michael G. Hogg
Fibroblasts derived from distinct anatomical regions appear to differ in regard to their behavior in culture. These differences may reflect functions of these cells in vivo that are tissue specific. Moreover, intrinsic differences in fibroblasts may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1d8f22bfe08f9dad930aee0d0fbff7
https://europepmc.org/articles/PMC43938/
https://europepmc.org/articles/PMC43938/