Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Michael G. Borland"'
Autor:
Bokai Zhu, Xiaoyang Zhu, Michael G. Borland, Douglas H. Ralph, Christopher R. Chiaro, Kristopher W. Krausz, James M. Ntambi, Adam B. Glick, Andrew D. Patterson, Gary H. Perdew, Frank J. Gonzalez, Jeffrey M. Peters
Publikováno v:
Biomolecules, Vol 14, Iss 6, p 606 (2024)
Nuclear hormone receptors exist in dynamic equilibrium between transcriptionally active and inactive complexes dependent on interactions with ligands, proteins, and chromatin. The present studies examined the hypothesis that endogenous ligands activa
Externí odkaz:
https://doaj.org/article/231cd6ff406947e89aa731b290f06494
Autor:
Michael G. Borland, Dae Joon Kim, Moses T. Bility, Jeffrey M. Peters, Frank J. Gonzalez, Bokai Zhu
Publikováno v:
Mol Carcinog
Considerable progress has been made during the past 20 years towards elucidating the role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) in skin cancer. In 1999, the original notion that PPARβ/δ was involved with epithelial cell fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80ca53144c13afb711ea6ae0f901da41
https://doi.org/10.1002/mc.23033
https://doi.org/10.1002/mc.23033
Autor:
Bokai Zhu, Brooke E. Shannon, Christina Lee, Ashley L. Wagner, Jeffrey M. Peters, Ellen M. Kehres, Frank J. Gonzalez, Michael G. Borland, Prajakta P. Albrecht
Publikováno v:
Toxicology. :25-32
To examine the functional role of peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) and PPARγ in skin cancer, stable cell lines were created in the A431 human squamous cell carcinoma cell line. Expression of PPAR target genes was greatly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30ac22f140a61f6aceed546c84293302
https://doi.org/10.1016/j.tox.2018.05.003
https://doi.org/10.1016/j.tox.2018.05.003
Autor:
Elizabeth Ola, Christina Lee, Bokai Zhu, Ashley L. Wagner, Boo Hyon Kang, Frank J. Gonzalez, Michael G. Borland, Jeffrey M. Peters, Prajakta P. Albrecht, Pei-Li Yao, Brooke E. Shannon, Ellen M. Kehres, Amanda M. Pritzlaff, Gavin P. Robertson
Publikováno v:
Toxicological Sciences. 159:436-448
Skin tumorigenesis results from DNA damage, increased inflammation, and evasion of apoptosis. The peroxisome proliferator-activated receptors (PPARs) can modulate these mechanisms in non-melanoma skin cancer. However, limited data exists regarding th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16e7da6c22064af752361602b069b02f
https://doi.org/10.1093/toxsci/kfx147
https://doi.org/10.1093/toxsci/kfx147
Autor:
Jeffrey M. Peters, Craig B. Marcus, Prasad Krishnan, Michael G. Borland, Weiwei Shan, Christina Lee, Gary H. Perdew, Jyh M. Lin, Frank J. Gonzalez, Moses T. Bility, Prajakta P. Albrecht, Shantu Amin
Publikováno v:
Carcinogenesis. 35:1602-1612
Whether peroxisome proliferator-activated receptor β/δ (PPARβ/δ) reduces skin tumorigenesis by altering aryl hydrocarbon receptor (AHR)-dependent activities was examined. Polycyclic aromatic hydrocarbons (PAH) increased expression of cytochrome P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e438fcbb07fbd242c13d9882def9343d
https://doi.org/10.1093/carcin/bgu067
https://doi.org/10.1093/carcin/bgu067
Publikováno v:
Biochemistry and Molecular Biology Education. 41:242-250
Spectrophotometric analysis is essential for determining biomolecule concentration of a solution and is employed ubiquitously in biochemistry and molecular biology. The application of the Beer-Lambert-Bouguer Lawis routinely used to determine the con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f9cdfb3f3a4586cad5c9174bd7bd6ae5
https://doi.org/10.1002/bmb.20694
https://doi.org/10.1002/bmb.20694
Autor:
Wen-Chi L. Chang, Bokai Zhu, Jeffrey M. Peters, Michael G. Borland, Frank J. Gonzalez, Jennie L. Williams, Lance R. Kramer, Prajakta S. Palkar, Jennifer E. Foreman, Margie L. Clapper
Publikováno v:
Molecular Carcinogenesis. 50:884-900
This study critically examined the role of PPARb/d in colon cancer models. Expression of PPARb/d mRNA and protein was lower and expression of CYCLIN D1 protein higher in human colon adenocarcinomas compared to matched nontransformed tissue. Similar r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c35a83c8282ca9993a84df82a80a02a
https://doi.org/10.1002/mc.20757
https://doi.org/10.1002/mc.20757
Autor:
Massimo Curini, Jennifer E. Foreman, Salvatore Genovese, Francesco Epifano, Jeffrey M. Peters, Frank J. Gonzalez, Michael G. Borland
Publikováno v:
Life Sciences. 86:493-498
Aims Previous studies showed that natural prenyloxyphenylpropanoid derivatives have potent biological properties in vivo . Given the structural similarities between these compounds and known peroxisome proliferator-activated receptor (PPAR) agonists,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7c10295308f57d1b4056d686a4dd914
https://doi.org/10.1016/j.lfs.2010.02.008
https://doi.org/10.1016/j.lfs.2010.02.008
Autor:
Shantu Amin, Karam El-Bayoumy, Michael G. Borland, Frank J. Gonzalez, Arun Sharma, Pengfei He, Bokai Zhu, Jeffrey M. Peters
Publikováno v:
Toxicology. 254:112-117
There is compelling evidence that peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) mediates terminal differentiation and is associated with inhibition of cell growth. However, it was recently suggested that growth of two human lung cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6de31968709e086e84d38b1109cec138
https://doi.org/10.1016/j.tox.2008.09.023
https://doi.org/10.1016/j.tox.2008.09.023
Autor:
Timothy M. Willson, Michael G. Borland, Jeffrey M. Peters, Holly E. Hollingshead, Frank J. Gonzalez, Andrew N. Billin
Publikováno v:
Carcinogenesis. 29:169-176
Cyclooxygenase (COX) 2-derived prostaglandin E(2) (PGE(2)) promotes colorectal carcinoma growth and invasion, and inhibition of COX2 by non-steroidal anti-inflammatory drugs is known to inhibit these processes. There is controversy regarding the effe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2df5076362d6d90b6b98fe0db8872fcf
https://doi.org/10.1093/carcin/bgm209
https://doi.org/10.1093/carcin/bgm209