Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michael G Morash"'
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115305 (2014)
The smoking of tobacco continues to be the leading cause of premature death worldwide and is linked to the development of a number of serious illnesses including heart disease, respiratory diseases, stroke and cancer. Currently, cell line based toxic
Externí odkaz:
https://doaj.org/article/df3f1cd27a914cd49ca54213c676db0b
Autor:
Michael G. Morash, Jessica Nixon, Lori M. N. Shimoda, Helen Turner, Alexander J. Stokes, Andrea L. Small-Howard, Lee D. Ellis
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Medicinal cannabis has shown promise for the symptomatic treatment of Parkinson’s disease (PD), but patient exposure to whole plant mixtures may be undesirable due to concerns around safety, consistency, regulatory issues, and psychoactivity. Ident
Externí odkaz:
https://doaj.org/article/4209c1573dbf455f9fcc70830700ff22
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7985 (2022)
Catechol is a ubiquitous chemical used in the manufacturing of fragrances, pharmaceuticals and flavorants. Environmental exposure occurs in a variety of ways through industrial processes, during pyrolysis and in effluent, yet despite its prevalence,
Externí odkaz:
https://doaj.org/article/cc0186a6198e4db9bf930bd21fd5e166
Autor:
Michael G. Morash, Susan E. Douglas, Anna Robotham, Christina M. Ridley, Jeffrey W. Gallant, Kelly H. Soanes
Publikováno v:
Disease Models & Mechanisms, Vol 4, Iss 5, Pp 622-633 (2011)
SUMMARY The emergence of multidrug-resistant cancers and the lack of targeted therapies for many cancers underscore an unmet need for new therapeutics with novel modes of action towards cancer cells. Host-defense peptides often exhibit selective cyto
Externí odkaz:
https://doaj.org/article/eaf4d1734a454887b5a6c91aeb28d389
Autor:
Fabrice Berrué, Jessica A. Hill, Lee D. Ellis, Michael G. Morash, John C. Achenbach, Jason J. McDougall
Publikováno v:
Behavioural brain research. 337
It has been established that both adult and larval zebrafish are capable of showing nociceptive responses to noxious stimuli; however, the use of larvae to test novel analgesics has not been fully explored. Zebrafish larvae represent a low-cost, high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06e72c56bbdcd571dc523f6eb76abc56
https://pubmed.ncbi.nlm.nih.gov/28935439
https://pubmed.ncbi.nlm.nih.gov/28935439
Publikováno v:
General and Comparative Endocrinology. 162:179-187
Prohormone convertase subtilisin/kexin (PCSK) enzymes are a family of nine related serine proteases, found in a multitude of tissues, and responsible for the maturation of a variety of protein and peptide precursors. Pcsk1 and Pcsk2 are found within
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4311aec7d0bfdcaa164837cff9fec480
https://doi.org/10.1016/j.ygcen.2009.03.013
https://doi.org/10.1016/j.ygcen.2009.03.013
Autor:
Paul S. Hoffman, Michael G. Morash, Rafael A. Garduño, Poornima Gourabathini, Michelle Warthan, Steven D. Goodman, Ann Karen C. Brassinga
Publikováno v:
Applied and Environmental Microbiology. 75:1826-1837
Legionella pneumophila is an intracellular parasite of protozoa that differentiates late in infection into metabolically dormant cysts that are highly infectious. Regulation of this process is poorly understood. Here we report that the small DNA bind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d641fe26edc519f2ce43133f21fe2381
https://doi.org/10.1128/aem.02756-08
https://doi.org/10.1128/aem.02756-08
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115305 (2014)
PLoS ONE
PLoS ONE
The smoking of tobacco continues to be the leading cause of premature death worldwide and is linked to the development of a number of serious illnesses including heart disease, respiratory diseases, stroke and cancer. Currently, cell line based toxic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5c646766d5a4f3880a75fe4a0cc8ab0
https://nrc-publications.canada.ca/eng/view/object/?id=2cb6387c-1213-4286-8cd9-515bcef391ad
https://nrc-publications.canada.ca/eng/view/object/?id=2cb6387c-1213-4286-8cd9-515bcef391ad
Autor:
Charles J. Shoemaker, Paul S. Hoffman, Ann Karen C. Brassinga, Matthew A. Croxen, Jason J. LeBlanc, Michael G. Morash
This chapter tests the feasibility of replacing the sacB gene with another suicide gene, rdxA, from Helicobacter pylori, which encodes an NADPH oxygen insensitive nitroreductase. The authors show that the improved suicide vector pKBOXR (rdxA) and use
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b805942b7dac6ad4feede00632c3ef8
https://doi.org/10.1128/9781555815660.ch82
https://doi.org/10.1128/9781555815660.ch82
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 768
Proprotein convertases (PCs) are secretory proteolytic enzymes that activate precursor proteins into biologically active forms by limited proteolysis at one or multiple internal sites. PCs are implicated in the processing of multiple protein precurso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::db56332729bcfccb9bf05a4896d4a24d
https://pubmed.ncbi.nlm.nih.gov/21805248
https://pubmed.ncbi.nlm.nih.gov/21805248