Zobrazeno 1 - 10
of 277
pro vyhledávání: '"Michael G Harrington"'
Autor:
Mark R Libowitz, Ke Wei, Thao Tran, Karen Chu, Kristina Moncrieffe, Michael G Harrington, Kevin King
Publikováno v:
PLoS ONE, Vol 16, Iss 7, p e0254332 (2021)
We hypothesized that automated assessment of brain volumes on MRI can predict presence of cerebrospinal fluid abnormal ß-amyloid42 and Tau protein levels and thus serve as a useful screening test for possible Alzheimer's disease. 113 participants ra
Externí odkaz:
https://doaj.org/article/f1216906069a4bd4931a901de9a329bd
Autor:
Alfred N. Fonteh, Abby J. Chiang, Xianghong Arakaki, Sarah P. Edminster, Michael G Harrington
Publikováno v:
Frontiers in Neuroscience, Vol 14 (2020)
Insight into lipids’ roles in Alzheimer’s disease (AD) pathophysiology is limited because brain membrane lipids have not been characterized in cognitively healthy (CH) individuals. Since age is a significant risk factor of AD, we hypothesize that
Externí odkaz:
https://doaj.org/article/2802687c7a7b4401979f6a80c8a8deaf
Autor:
Angela J Oh, Giulia Amore, William Sultan, Samuel Asanad, Jason C Park, Martina Romagnoli, Chiara La Morgia, Rustum Karanjia, Michael G Harrington, Alfredo A Sadun
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0230061 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0226197.].
Externí odkaz:
https://doaj.org/article/b756ba5f1fe54e9ab39648443794271d
Autor:
Samuel Asanad, Michele Fantini, William Sultan, Marco Nassisi, Christian M Felix, Jessica Wu, Rustum Karanjia, Fred N Ross-Cisneros, Abhay P Sagare, Berislav V Zlokovic, Helena C Chui, Janice M Pogoda, Xianghong Arakaki, Alfred N Fonteh, Alfredo A Sadun, Michael G Harrington
Publikováno v:
PLoS ONE, Vol 15, Iss 7, p e0236379 (2020)
[This corrects the article DOI: 10.1371/journal.pone.0232785.].
Externí odkaz:
https://doaj.org/article/c52172f700a34ae893becc4cff9ef3ac
Autor:
Samuel Asanad, Michele Fantini, William Sultan, Marco Nassisi, Christian M Felix, Jessica Wu, Rustum Karanjia, Fred N Ross-Cisneros, Abhay P Sagare, Berislav V Zlokovic, Helena C Chui, Janice M Pogoda, Xianghong Arakaki, Alfred N Fonteh, Alfredo A Sadun, Michael G Harrington
Publikováno v:
PLoS ONE, Vol 15, Iss 5, p e0232785 (2020)
BackgroundAlzheimer's disease (AD) pathology precedes symptoms and its detection can identify at-risk individuals who may benefit from early treatment. Since the retinal nerve fiber layer (RNFL) is depleted in established AD, we tested whether its th
Externí odkaz:
https://doaj.org/article/325616b7ffac4b298499a34310d35be5
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0208517 (2019)
Our aim is to explore if cognitive challenge combined with objective physiology can reveal abnormal frontal alpha event-related desynchronization (ERD), in early Alzheimer's disease (AD). We used quantitative electroencephalography (qEEG) to investig
Externí odkaz:
https://doaj.org/article/6597a7a4c9bf4b9da34f0a582aa80784
Autor:
Angela J Oh, Giulia Amore, William Sultan, Samuel Asanad, Jason C Park, Martina Romagnoli, Chiara La Morgia, Rustum Karanjia, Michael G Harrington, Alfredo A Sadun
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226197 (2019)
BACKGROUND:Melanopsin-expressing retinal ganglion cells (mRGCs), intrinsically photosensitive RGCs, mediate the light-based pupil response and the light entrainment of the body's circadian rhythms through their connection to the pretectal nucleus and
Externí odkaz:
https://doaj.org/article/767546a9d63d42eab7519180dc83af21
Autor:
Noah B Gross, Nastaren Abad, David Lichtstein, Shiri Taron, Lorena Aparicio, Alfred N Fonteh, Xianghong Arakaki, Robert P Cowan, Samuel C Grant, Michael G Harrington
Publikováno v:
PLoS ONE, Vol 14, Iss 6, p e0218041 (2019)
There is strong evidence that neuronal hyper-excitability underlies migraine, and may or may not be preceded by cortical spreading depression. However, the mechanisms for cortical spreading depression and/or migraine are not established. Previous stu
Externí odkaz:
https://doaj.org/article/ca06980f603f4dfcb9d3ee23e81d5a32
Autor:
Xianghong Arakaki, Michael Shoga, Lianyang Li, George Zouridakis, Thao Tran, Alfred N Fonteh, Jessica Dawlaty, Robert Goldweber, Janice M Pogoda, Michael G Harrington
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0188101 (2018)
Diagnosing and monitoring recovery of patients with mild traumatic brain injury (mTBI) is challenging because of the lack of objective, quantitative measures. Diagnosis is based on description of injuries often not witnessed, subtle neurocognitive sy
Externí odkaz:
https://doaj.org/article/e270493fbc814c52b619bdc5be1bd6ee
Autor:
Alfred N Fonteh, Cora Ormseth, Jiarong Chiang, Matthew Cipolla, Xianghong Arakaki, Michael G Harrington
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0125597 (2015)
Sphingolipids are important in many brain functions but their role in Alzheimer's disease (AD) is not completely defined. A major limit is availability of fresh brain tissue with defined AD pathology. The discovery that cerebrospinal fluid (CSF) cont
Externí odkaz:
https://doaj.org/article/2c4d38a7c7f9473e97a38effcc21ec86