Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Michael G Drage"'
Autor:
Michael Griffin, Sandhya Srinivasan, Jake Conway, Benjamin Glass, Fedaa Najdawi, Ciyue Shen, Shima Nofallah, Chintan Parmar, Michael G Drage, Darpan T Sanghavi, Limin Yu, Raymond Biju, Daniel Borders, Matthew Bronnimann, Laura Chambre, Issac Finberg, Jonathan Glickman, Sidharth Gupta, Natalia Harguindeguy, Nhat Le, Stephanie Hennek, Syed Ashar Javed, Christian Kirkup, Miles Markey, Michael Nercessian, Daniel Shenker, Vignesh Valaboju, Samuel AV Mercedes, Bahar Rahsepar, Ryan Leung, Archit Khosla, Amaro Taylor-Weiner, Ylaine Gerardin, John Abel
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/f3f11b9b5b2b4183b35fd446b2be9291
Autor:
Taylor P. Uccello, MS, Sarah A. Kintzel, BS, Bradley N. Mills, PhD, Joseph D. Murphy, MS, Jesse Garrett-Larsen, BS, Nicholas G. Battaglia, PhD, Carlos J. Rodriguez, BS, Michael G. Drage, MD, Jian Ye, PhD, Tanzy M.T. Love, PhD, Carl J. Johnston, PhD, Elizabeth A. Repasky, PhD, Haoming Qiu, MD, David C. Linehan, MD, Edith M. Lord, PhD, Scott A. Gerber, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 7, Iss 2, Pp 100867- (2022)
Purpose: Orthotopic tumors more closely recapitulate human cancers than do ectopic models; however, precision targeting of such internal tumors for radiation therapy (RT) without inducing systemic toxicity remains a barrier. We developed an innovativ
Externí odkaz:
https://doaj.org/article/e6a54b79ca5a4a35a5fb31b880e6b168
Autor:
Taylor P. Uccello, Maggie L. Lesch, Nicholas A. Ullman, Sarah A. Kintzel, Lauren B. Gradzewicz, Trishna Velagaleti, Fergal J. Fleming, Bradley N. Mills, Joseph D. Murphy, Jesse Garrett-Larsen, Haoming Qiu, Michael G. Drage, Jian Ye, Nicholas W. Gavras, Carl J. Johnston, Tanzy M.T. Love, Elizabeth A. Repasky, David C. Linehan, Edith M. Lord, Scott A. Gerber
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 115:733-745
Many solid tumors present with perineural invasion (PNI), and innervation correlates with worsened prognosis. The effects that commonly administered therapies such as radiation therapy (RT) have on PNI status remain unknown. We investigated the contr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69b56771ec717c81948508072dea4336
https://doi.org/10.1016/j.ijrobp.2022.09.080
https://doi.org/10.1016/j.ijrobp.2022.09.080
Autor:
John Abel, Christian Kirkup, Filip Kos, Ylaine Gerardin, Sandhya Srinivasan, Jacqueline Brosnan-Cashman, Ken Leidal, Sanjana Vasudevan, Deepta Rajan, Suyog Jain, Aaditya Prakash, Harshith Padigela, Jake Conway, Neel Patel, Benjamin Trotter, Limin Yu, Amaro Taylor-Weiner, Emma L. Krause, Matthew Bronnimann, Laura Chambre, Ben Glass, Chintan Parmar, Stephanie Hennek, Archit Khosla, Murray Resnick, Andrew H. Beck, Michael Montalto, Fedaa Najdawi, Michael G. Drage, Ilan Wapinski
Publikováno v:
Cancer Research. 83:P4-09
Background: Morphological features of cancer cell nuclei are routinely used to assess disease severity and prognosis, and cancer nuclear morphology has been linked to genomic alterations. Quantitative analyses of the nuclear features of cancer cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2e46cbcad1f37fe7eb9010d40aed9af4
https://doi.org/10.1158/1538-7445.sabcs22-p4-09-08
https://doi.org/10.1158/1538-7445.sabcs22-p4-09-08
Autor:
Bradley N. Mills, Kelli A. Connolly, Jian Ye, Joseph D. Murphy, Taylor P. Uccello, Booyeon J. Han, Tony Zhao, Michael G. Drage, Aditi Murthy, Haoming Qiu, Ankit Patel, Nathania M. Figueroa, Carl J. Johnston, Peter A. Prieto, Nejat K. Egilmez, Brian A. Belt, Edith M. Lord, David C. Linehan, Scott A. Gerber
Publikováno v:
Cell Reports, Vol 29, Iss 2, Pp 406-421.e5 (2019)
Summary: Over 80% of pancreatic ductal adenocarcinoma (PDA) patients are diagnosed with non-resectable late-stage disease that lacks effective neoadjuvant therapies. Stereotactic body radiation therapy (SBRT) has shown promise as an emerging neoadjuv
Externí odkaz:
https://doaj.org/article/4e46e83b18694648a2d984f0afc1f88a
Autor:
John Abel, Suyog Jain, Deepta Rajan, Harshith Padigela, Kenneth Leidal, Aaditya Prakash, Jake Conway, Michael Nercessian, Christian Kirkup, Syed Ashar Javed, Robert Egger, Benjamin Trotter, Ylaine Gerardin, Jacqueline A. Brosnan-Cashman, Aditya Dhoot, Michael C. Montalto, Ilan Wapinski, Archit Khosla, Michael G. Drage, Limin Yu, Amaro Taylor-Weiner
BackgroundAltered nuclei are ubiquitous in cancer, with changes in nuclear size, shape, and coloration accompanying cancer progression. However, comprehensive quantification of nuclear morphology across a whole-slide histologic image remains a challe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4c59ac25a98f713a20668d5539415ee5
https://doi.org/10.1101/2023.05.15.539600
https://doi.org/10.1101/2023.05.15.539600
Publikováno v:
The Journal of Pathology. 257:186-197
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d6f89c053e5405e8ff362e8195ffddb
https://doi.org/10.1002/path.5877
https://doi.org/10.1002/path.5877
Autor:
Haoming Qiu, Alan W. Katz, David C. Linehan, Bradley N. Mills, Edith M. Lord, Jocelyn S Mathew, Jesse Garrett-Larsen, Chunmo Chen, Michael G. Drage, Scott A. Gerber, Taylor P Uccello, Joseph D Murphy, Brian A. Belt, Jian Ye
Publikováno v:
Clinical Cancer Research. 28:150-162
Purpose: Stereotactic body radiotherapy (SBRT) is an emerging treatment modality for pancreatic ductal adenocarcinoma (PDAC), which can effectively prime cytotoxic T cells by inducing immunogenic tumor cell death in preclinical models. SBRT effects o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::907b1dd36dd4eb182a15392816256a8d
https://doi.org/10.1158/1078-0432.ccr-21-2495
https://doi.org/10.1158/1078-0432.ccr-21-2495
Autor:
Brian M. Wolpin, Jonathan A. Nowak, Shuji Ogino, Aram F. Hezel, Albert C. Koong, Daniel T. Chang, Lisa M. Coussens, Charles S. Fuchs, Andrew J. Aguirre, David C. Linehan, Jiping Wang, Thomas Clancy, Osama Rahma, Emma Reilly, Lauren Brais, Michael G. Drage, Diana Agostini-Vulaj, Wenjia Wang, Margaret M. Kozak, Richard F. Dunne, Douglas A. Rubinson, Mai Chan Lau, Vicente Morales-Oyarvide, Hannah Williams, Andressa Dias Costa, Juha P. Väyrynen, Chen Yuan, Jinming Zhang, Sara A. Väyrynen
Supplementary Tables S1-S14 and Supplementary Figures S1-S9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbcc1d5c2121bc92e7353649f16bfc83
https://doi.org/10.1158/1078-0432.22479263.v1
https://doi.org/10.1158/1078-0432.22479263.v1
Autor:
Brian M. Wolpin, Jonathan A. Nowak, Shuji Ogino, Aram F. Hezel, Albert C. Koong, Daniel T. Chang, Lisa M. Coussens, Charles S. Fuchs, Andrew J. Aguirre, David C. Linehan, Jiping Wang, Thomas Clancy, Osama Rahma, Emma Reilly, Lauren Brais, Michael G. Drage, Diana Agostini-Vulaj, Wenjia Wang, Margaret M. Kozak, Richard F. Dunne, Douglas A. Rubinson, Mai Chan Lau, Vicente Morales-Oyarvide, Hannah Williams, Andressa Dias Costa, Juha P. Väyrynen, Chen Yuan, Jinming Zhang, Sara A. Väyrynen
Purpose:Although abundant myeloid cell populations in the pancreatic ductal adenocarcinoma (PDAC) microenvironment have been postulated to suppress antitumor immunity, the composition of these populations, their spatial locations, and how they relate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e49efa06fd67c2ca69c7dc92c67a97
https://doi.org/10.1158/1078-0432.c.6530165
https://doi.org/10.1158/1078-0432.c.6530165