Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Michael G Constantinides"'
Publikováno v:
Cell hostmicrobe. 30(7)
The pathogenicity of disease-associated microbes varies widely between individuals. In this issue of Cell HostMicrobe, Rice et al. demonstrate that interactions between intestinal commensals reciprocally modulate the host immune response to each micr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c8d925213bd2d16f7d6e5c6eabbc36d
https://pubmed.ncbi.nlm.nih.gov/35640610
https://pubmed.ncbi.nlm.nih.gov/35640610
Publikováno v:
Science
Atypical T cells take a different path Conventional T cells recognize peptides that are presented by polymorphic major histocompatibility complexes (MHCs). By contrast, many tissue-resident T cells, such as mucosal-associated invariant T cells, invar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::413fa8d6f40b01fc21c0099eb636e78f
https://doi.org/10.1126/science.abf0095
https://doi.org/10.1126/science.abf0095
Autor:
Gabrielle LeBlanc, Felix K. Kreissl, Jonathan Melamed, Adam L. Sobel, Michael G. Constantinides
Publikováno v:
Semin Immunol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1eaff49dfa9df8dc3043ebf1f81dfed
https://doi.org/10.1016/j.smim.2022.101656
https://doi.org/10.1016/j.smim.2022.101656
Autor:
Samira Tamoutounour, Michael A. Fischbach, Y. Erin Chen, Michael G. Constantinides, Nicolas Bouladoux, Yasmine Belkaid, E. Merrill, Jan Claesen, Allyson L. Byrd, Vanessa K. Ridaura
Publikováno v:
Journal of Experimental Medicine. 215:785-799
How defined microbes influence the skin immune system remains poorly understood. Here we demonstrate that Corynebacteria, dominant members of the skin microbiota, promote a dramatic increase in the number and activation of a defined subset of γδ T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa9d98eb10b933614994eb5b9ce5d706
https://doi.org/10.1084/jem.20171079
https://doi.org/10.1084/jem.20171079
Autor:
Nicholas Collins, Verena M. Link, George Kassiotis, Erin Y. Chen, Michael G. Constantinides, Jan Attig, Christophe Cataisson, Yasmine Belkaid, Djalma S. Lima-Junior, G. I. Koroleva, Taylor K. Farley, Stuart H. Yuspa, Michel Enamorado, Nicolas Bouladoux, Michael A. Fischbach, Louis Gil, Ai Ing Lim, Siddharth R. Krishnamurthy, Indira Rao, Seong-Ji Han
Publikováno v:
Cell
Summary The microbiota plays a fundamental role in regulating host immunity. However, the processes involved in the initiation and regulation of immunity to the microbiota remain largely unknown. Here, we show that the skin microbiota promotes the di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b782596d0350a3f1bcfbe9b075b67f91
https://doi.org/10.1038/s41577-021-00587-y
https://doi.org/10.1038/s41577-021-00587-y
Autor:
Michael G. Constantinides
Publikováno v:
Journal of Leukocyte Biology. 103:409-419
The microbiota, which consists of commensal bacteria, fungi, and viruses, limits the colonization of pathogens at barrier tissues and promotes immune homeostasis. The latter is accomplished through the induction and regulation of both innate and adap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcd4b0ff7029ab60f85fac7eac27907
https://doi.org/10.1002/jlb.3ri0917-378r
https://doi.org/10.1002/jlb.3ri0917-378r
Autor:
Jonathan L. Linehan, Paula Juliana Pérez-Chaparro, Barbara Rehermann, Oliver J. Harrison, Ivan Vujkovic-Cvijin, Vanja Lazarevic, Michael G. Constantinides, Samira Tamoutounour, Julie Deckers, Seong-Ji Han, Nicolas Bouladoux, Stephan P. Rosshart, C. Hurabielle, Verena M. Link, Yasmine Belkaid
Publikováno v:
Proc Natl Acad Sci U S A
The cross-talk between the microbiota and the immune system plays a fundamental role in the control of host physiology. However, the tissue-specific factors controlling this dialogue remain poorly understood. Here we demonstrate that T cell responses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f40a77acd98df21ba19a759b971a4ea9
https://pubmed.ncbi.nlm.nih.gov/31672911
https://pubmed.ncbi.nlm.nih.gov/31672911
Autor:
Tiffany C. Scharschmidt, Yasmine Belkaid, Sepideh Farhat, E. Dean Merrill, Andrea C. Wong, Samira Tamoutounour, Kelin Li, Michael G. Constantinides, Ivan Vujkovic-Cvijin, Jonathan L. Linehan, Antonin Weckel, Jeffrey Aubé, Avinash Bhandoola, Verena M. Link, Sobhan Roy, Daniel J. Cua, Siddharth R. Krishnamurthy, Erin J. Adams, Michael A. Fischbach, P. Juliana Perez-Chaparro, Nicolas Bouladoux, Seong-Ji Han, Y. Erin Chen
Publikováno v:
Science (New York, N.Y.), vol 366, iss 6464
Commensals rule the MAITrix Mucosal-associated invariant T (MAIT) cells play an important role in mucosal homeostasis. MAIT cells recognize microbial small molecules presented by the major histocompatibility complex class Ib molecule MR1. MAIT cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10f0834252303e9b09428e3de1d93ab5
Autor:
Herman Gudjonson, Rachel Golub, Sylvestre Chea, Aaron R. Dinner, Michael G. Constantinides, Isabel E. Ishizuka, Albert Bendelac
Publikováno v:
Nature Immunology
Nature Immunology, Nature Publishing Group, 2016, 17 (3), pp.269-76. ⟨10.1038/ni.3344⟩
Nature Immunology, 2016, 17 (3), pp.269-76. ⟨10.1038/ni.3344⟩
Nature Immunology, Nature Publishing Group, 2016, 17 (3), pp.269-76. ⟨10.1038/ni.3344⟩
Nature Immunology, 2016, 17 (3), pp.269-76. ⟨10.1038/ni.3344⟩
International audience; The precise lineage relationship between innate lymphoid cells (ILCs) and lymphoid tissue-inducer (LTi) cells is poorly understood. Using single-cell multiplex transcriptional analysis of 100 lymphoid genes and single-cell cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcad901f3e1b82d7ec5d19c73b722526
https://doi.org/10.1038/ni.3344
https://doi.org/10.1038/ni.3344
Autor:
Rebecca Mathew, Seth T. Scanlon, Kristin Hollister, Benjamin D. McDonald, Alexander L. Dent, Albert Bendelac, Aaron R. Dinner, Jeffrey J. Bunker, Michael G. Constantinides, Jeffrey D. Singer, Andrew H. Chiang, Ai-Ping Mao, Clara Bertozzi-Villa
Publikováno v:
The Journal of Experimental Medicine
Bcl6 and E3 ligase cullin 3 complexes mediate negative feedback regulation during thymocyte development and T cell activation to restrain exaggerated Tfh responses.
Induction of Bcl6 (B cell lymphoma 6) is essential for T follicular helper (Tfh)
Induction of Bcl6 (B cell lymphoma 6) is essential for T follicular helper (Tfh)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8748e13730cba52dfd3555836c4ddb8
https://doi.org/10.1084/jem.20132267
https://doi.org/10.1084/jem.20132267