Zobrazeno 1 - 10
of 296
pro vyhledávání: '"Michael G Brown"'
Autor:
Ileana S Mauldin, Craig L Slingluff, Nolan A Wages, Timothy N J Bullock, Remziye E Wessel, Nardin Ageeb, Joseph M Obeid, Kate A Goundry, Gabriel F Hanson, Mahdin Hossain, Chad Lehman, Ryan D Gentzler, Sepideh Dolatshahi, Michael G Brown
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 9 (2024)
Background Major histocompatibility complex class I (MHC-I) loss is frequent in non-small cell lung cancer (NSCLC) rendering tumor cells resistant to T cell lysis. NK cells kill MHC-I-deficient tumor cells, and although previous work indicated their
Externí odkaz:
https://doaj.org/article/0caeecd399cd42da95bec43ad9df45a7
Autor:
Alyssa Lundgren Gillespie, Jeffrey Teoh, Heather Lee, Jessica Prince, Michael D Stadnisky, Monique Anderson, William Nash, Claudia Rival, Hairong Wei, Awndre Gamache, Charles R Farber, Kenneth Tung, Michael G Brown
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005419 (2016)
The MHC class I D(k) molecule supplies vital host resistance during murine cytomegalovirus (MCMV) infection. Natural killer (NK) cells expressing the Ly49G2 inhibitory receptor, which specifically binds D(k), are required to control viral spread. The
Externí odkaz:
https://doaj.org/article/4e8079d535a444719ff10e085e52a946
Publikováno v:
Frontiers in Immunology, Vol 5 (2014)
Natural killer cells (NK) provide essential protection against viral infections. One of the defining features of this lymphocyte population is the expression of a wide array of variable cell surface stimulatory and inhibitory NK receptors (sNKR and i
Externí odkaz:
https://doaj.org/article/83274d52e8ff4d3bab6f8162306522ec
Autor:
Yi-Ting Fang, Shu-Wen Wan, Yi-Tien Lu, Ju-Han Yao, Chiou-Feng Lin, Li-Jin Hsu, Michael G Brown, Jean S Marshall, Robert Anderson, Yee-Shin Lin
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e110655 (2014)
Dengue virus (DENV) infection can cause severe hemorrhagic disease in humans. Although the pathogenic mechanisms underlying severe DENV disease remain unclear, one of the possible contributing factors is antibody-dependent enhancement (ADE) which occ
Externí odkaz:
https://doaj.org/article/f7e2ba90df25423ba6009e57f55217d5
Autor:
Michael G Brown, Sarah M McAlpine, Yan Y Huang, Ian D Haidl, Ayham Al-Afif, Jean S Marshall, Robert Anderson
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e34055 (2012)
Dengue hemorrhagic fever and/or dengue shock syndrome represent the most serious pathophysiological manifestations of human dengue virus infection. Despite intensive research, the mechanisms and important cellular players that contribute to dengue di
Externí odkaz:
https://doaj.org/article/83932672101b43b29516d14dcfe88f64
Autor:
Komi Gbedande, Samad A. Ibitokou, Monique L. Ong, Mariapia A. Degli-Esposti, Michael G. Brown, Robin Stephens
Publikováno v:
bioRxiv
Vaccines to persistent parasite infections have been challenging, and current iterations lack long-term protection. Cytomegalovirus(CMV) chronic vaccine vectors drive protection against SIV, tuberculosis and liver-stage malaria correlated with antige
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6cdd4395e24ad046648bd01123f79cf
https://europepmc.org/articles/PMC10187235/
https://europepmc.org/articles/PMC10187235/
Autor:
Rachel A. Smith, Michael G. Brown, James J. Schiltz, Stephanie Sowl, Jessica M. Schulz, Kevin A. Grady
Publikováno v:
Innovative Higher Education.
Autor:
Kayla Wright, Son Tran, Tracey C. Vlahovic, Michael G. Brown, Benton Stewart, Kushkaran Kaur, Kari Phan
Publikováno v:
Clinics in Podiatric Medicine and Surgery. 38:535-540
The chemical composition and thickness of nails are obstacles for treatments of various nail diseases, such as onychomycosis. Topical medications are currently the preferred method of treatment because of reduced adverse systemic effects. However, pe
Autor:
John M. Cronk, Karolina H. Dziewulska, Patryk Puchalski, Rowena B. Crittenden, Marie-Louise Hammarskjöld, Michael G. Brown
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 209(8)
The murine CMV (MCMV) immunoevasin m04/gp34 escorts MHC class I (MHC I) molecules to the surface of infected cells where these complexes bind Ly49 inhibitory receptors (IRs) and prevent NK cell attack. Nonetheless, certain self–MHC I–binding Ly49
Publikováno v:
Hydrological Processes. 36