Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Michael G, Mykoniatis"'
Autor:
George K Papadimas, Konstantinos N Tzirogiannis, Michael G Mykoniatis, Agni D Grypioti, Georgia A Manta, Georgios I Panoutsopoulos
Publikováno v:
Swiss Medical Weekly, Vol 142, Iss 1516 (2012)
Serotonin has a multifunctional role in many different organs serving either as a neurotransmitter in the central nervous system or a paracrine factor in the gastrointestinal tract. Over 90% of serotonin is synthesised in the enterochromaffin cells o
Externí odkaz:
https://doaj.org/article/865ddff1607747d6af0140af237da26e
Autor:
Michael G. Mykoniatis, Loukas G. Kyriakou, Konstantinos N. Tzirogiannis, Kalliopi T. Kourentzi, Maria D. Demonakou, Georgios I Panoutsopoulos
Publikováno v:
Toxicology and Industrial Health. 29:624-632
Cadmium is a known industrial and environmental pollutant. It causes hepatotoxicity upon acute administration. Features of cadmium-induced acute hepatoxicity encompass necrosis, apoptosis, peliosis and inflammatory infiltration. Gadolinium chloride (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba3db8feca24c8c4338a95ec3751dba0
https://doi.org/10.1177/0748233711430971
https://doi.org/10.1177/0748233711430971
Autor:
Anastasios Roussos, Michael G. Mykoniatis, A. D. Grypioti, Constantinos A. Demopoulos, Georgia Kostopanagiotou
Publikováno v:
Digestive Diseases and Sciences. 53:1054-1062
Platelet activating factor (PAF) is an ubiquitous phospholipid that acts as a mediator of numerous pathophysiological conditions, including hepatotoxicity. The present study has been conducted to evaluate the eventual role of the platelet activating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd71c96d9b080947a8c285b756feb02b
https://doi.org/10.1007/s10620-007-9982-2
https://doi.org/10.1007/s10620-007-9982-2
Autor:
Vasilios P. Papastefanou, Evangelos Bozas, P. Nicolopoulou-Stamati, Stavros Garyfallidis, Christos S. Bartsocas, Michael G. Mykoniatis, A. D. Grypioti
Publikováno v:
Archives of Toxicology. 81:729-741
Acetaminophen (APAP) is a widely-used analgesic and a known hepatotoxic agent. Vascular endothelial growth factor (VEGF) is a growth factor with multiple functional roles. VEGF plays an important role in angiogenesis and hepatic regeneration. The aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b60f7537cc239a7b07e6d9ac309269
https://doi.org/10.1007/s00204-007-0201-x
https://doi.org/10.1007/s00204-007-0201-x
Autor:
Rosa I. Hereti, Konstantinos N. Tzirogiannis, Georgia A. Manta, Georgios I Panoutsopoulos, Spyridon D. Skaltsas, Maria D. Demonakou, Michael G. Mykoniatis, George K. Papadimas, Kalliopi T. Kourentzi, Katerina N. Alexandropoulou
Publikováno v:
Digestive Diseases and Sciences. 52:2351-2358
The protective effect of 5-HT(2) receptor blockade with ketanserin or ritanserin against cadmium liver injury was investigated. Male Wistar rats were injected intraperitoneally with a sublethal dose of cadmium (3.5 mg/kg body weight). Rats were treat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e10b6f87418f7b9b372e82be2da1134
https://doi.org/10.1007/s10620-006-9132-2
https://doi.org/10.1007/s10620-006-9132-2
Publikováno v:
Digestive Diseases and Sciences. 52:2580-2590
Platelet-activating factor (PAF) is a potent endogenous phospholipid modulator of diverse biological activities, including inflammation. The aim of this study was to investigate the effects of PAF inactivator, recombinant PAF acetylhydrolase (rPAF-AH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf2726ad54c125882ac2a58602f4529e
https://doi.org/10.1007/s10620-006-9728-6
https://doi.org/10.1007/s10620-006-9728-6
Autor:
George K. Papadimas, Rosa I. Hereti, Loukas G. Kyriakou, Michael G. Mykoniatis, Kalliopi T. Kourentzi, Maria D. Demonakou, Konstantinos N. Tzirogiannis, Vasiliki G. Kondyli, Georgios I Panoutsopoulos
Publikováno v:
Digestive Diseases and Sciences. 51:1998-2006
Macroscopic and microscopic types of peliosis hepatis, time pattern, and correlation with hepatocyte and sinusoidal cell apoptosis were investigated. Male Wistar rats were injected with a dose of cadmium (6.5 mg CdCl(2)/kg body weight, intraperitonea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed0ce731996bd4d857dc3cf2b4e2771b
https://doi.org/10.1007/s10620-006-9242-x
https://doi.org/10.1007/s10620-006-9242-x
Autor:
Konstantinos N. Tzirogiannis, Georgios I Panoutsopoulos, George K. Papadimas, Michael G. Mykoniatis, Rosa I. Hereti, Zeta Papadopoulou-Daifoti, Spyridon D. Skaltsas, Maria D. Demonakou
Publikováno v:
Liver International. 26:352-361
The effect of serotonin receptor 2 blockade (5-HT2) on liver regeneration after 30–34% and 60–70% partial hepatectomy in the rat liver was investigated. Materials and methods: Male Wistar rats were subjected to 60–70% (group I) and 30–34% (gr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1705c693fb0ba990d5ed6b3fc9079f07
https://doi.org/10.1111/j.1478-3231.2005.01230.x
https://doi.org/10.1111/j.1478-3231.2005.01230.x
Autor:
A. D. Grypioti, Z. Papadopoulou-Daifoti, Constantinos A. Demopoulos, Michael G. Mykoniatis, A. C. Basayiannis, Stamatios Theocharis
Publikováno v:
Liver International. 26:97-105
Background: Platelet-activating factor (PAF) is an endogenous lipid mediator that plays a key role in catalyzing various pro-inflammatory processes associated with acute liver injury. In the present study, the possible influence of PAF-R antagonist (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ef2811b8da75a1e1fdfa2f1741d0bcdf
https://doi.org/10.1111/j.1478-3231.2005.01186.x
https://doi.org/10.1111/j.1478-3231.2005.01186.x
Autor:
Michael G. Mykoniatis, Z. Papadopoulou-Daifoti, A. D. Grypioti, Constantinos A. Demopoulos, A. C. Basayiannis, George K. Papadimas, Stamatios Theocharis
Publikováno v:
Archives of Toxicology. 79:466-474
Acetaminophen-induced toxicity has been attributed to cytochrome P-450-generated metabolites, which covalently modify target proteins. However, the mechanism of liver injury pathogenesis needs to be further elucidated. Platelet-activating factor (PAF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f107661b0d308d5e0eab30e7a22b4c34
https://doi.org/10.1007/s00204-005-0651-y
https://doi.org/10.1007/s00204-005-0651-y