Zobrazeno 1 - 10
of 283
pro vyhledávání: '"Michael G, Dwyer"'
Autor:
Kian Jalaleddini, Dejan Jakimovski, Anisha Keshavan, Shannon McCurdy, Kelly Leyden, Ferhan Qureshi, Atiyeh Ghoreyshi, Niels Bergsland, Michael G. Dwyer, Murali Ramanathan, Bianca Weinstock‐Guttman, Ralph HB Benedict, Robert Zivadinov
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 11, Iss 3, Pp 729-743 (2024)
Abstract Background A quantitative measurement of serum proteome biomarkers that would associate with disease progression endpoints can provide risk stratification for persons with multiple sclerosis (PwMS) and supplement the clinical decision‐maki
Externí odkaz:
https://doaj.org/article/6608227ad3b546a09947ed62760a565f
Autor:
Dejan Jakimovski, Ryu P. Dorn, Megan Del Regno, Alexander Bartnik, Niels Bergsland, Murali Ramanathan, Michael G. Dwyer, Ralph H. B. Benedict, Robert Zivadinov, Kinga Szigeti
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
IntroductionCHRFAM7A, a uniquely human fusion gene, has been associated with neuropsychiatric disorders including Alzheimer’s disease, schizophrenia, anxiety, and attention deficit disorder. Understanding the physiological function of CHRFAM7A in t
Externí odkaz:
https://doaj.org/article/493eeae30ec648188dbf9fbac2508561
Autor:
Dejan Jakimovski, Robert Zivadinov, Ferhan Qureshi, Murali Ramanathan, Bianca Weinstock-Guttman, Eleonora Tavazzi, Michael G. Dwyer, Niels Bergsland
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 824 (2024)
Increased choroid plexus (CP) volume has been recently implicated as a potential predictor of worse multiple sclerosis (MS) outcomes. The biomarker signature of CP changes in MS are currently unknown. To determine the blood-based biomarker characteri
Externí odkaz:
https://doaj.org/article/71f57a4a5bb64bc08d717faeb472b75e
Autor:
Robert Zivadinov, Niels Bergsland, Dejan Jakimovski, Bianca Weinstock-Guttman, Lorena Lorefice, Menno M. Schoonheim, Sarah A. Morrow, Mary Ann Picone, Gabriel Pardo, Myassar Zarif, Mark Gudesblatt, Jacqueline A. Nicholas, Andrew Smith, Samuel Hunter, Stephen Newman, Mahmoud A. AbdelRazek, Ina Hoti, Jon Riolo, Diego Silva, Tom A. Fuchs, Michael G. Dwyer, Ralph HB. Benedict
Publikováno v:
NeuroImage: Clinical, Vol 42, Iss , Pp 103609- (2024)
Background: Prior research has established a link between thalamic pathology and cognitive impairment (CI) in people with multiple sclerosis (pwMS). However, the translation of these findings to pwMS in everyday clinical settings has been insufficien
Externí odkaz:
https://doaj.org/article/457ddb7a61bd4878b591acf720e64c6a
Autor:
Dejan Jakimovski, Robert Zivadinov, Laura Pelizzari, Cynthia Dunne-Jaffe, Richard W. Browne, Niels Bergsland, Michael G. Dwyer, Bianca Weinstock-Guttman, Murali Ramanathan
Publikováno v:
Veins and Lymphatics, Vol 11, Iss 1 (2022)
Background: Multiple sclerosis (MS) studies suggest greater cardiovascular disease burden and disturbances in the cholesterol pathways1,2 The potential impact of oxidized cholesterol molecules (oxysterols) on MS is emerging (Figure 1).3 Objective:
Externí odkaz:
https://doaj.org/article/c95b5dcabb08419fb3fb6a14aff1a1e9
Autor:
Nicholas Young, Robert Zivadinov, Michael G. Dwyer, Niels Bergsland, Bianca Weinstock-Guttman, Dejan Jakimovski
Publikováno v:
Veins and Lymphatics, Vol 11, Iss 1 (2022)
Background: Both greater retinal neurodegenerative pathology and greater cardiovascular burden have been seen in persons with multiple sclerosis (pwMS).1,2 Moreover, studies have described multiple extracranial and intracranial vasculature changes in
Externí odkaz:
https://doaj.org/article/e0bb44ce39f24268a6d3c49658a3141d
Autor:
Dejan Jakimovski, Brianna L. Gibney, Karen Marr, Deepa P. Ramasamy, Michael G. Dwyer, Niels Bergsland, Bianca Weinstock-Guttman, Murali Ramanathan, Robert Zivadinov
Publikováno v:
Veins and Lymphatics, Vol 11, Iss 1 (2022)
Background: Hypoperfusion, vascular pathology, and cardiovascular risk factors are associated with disease severity in multiple sclerosis (MS).1,2 In particular, the total cerebral arterial blood flow (CABF), measured as a sum of all arterial flow in
Externí odkaz:
https://doaj.org/article/3598483dedea44919d5a7db28525d01c
Autor:
Dejan Jakimovski, Niels Bergsland, Michael G. Dwyer, Kunsang Choedun, Karen Marr, Bianca Weinstock-Guttman, Robert Zivadinov
Publikováno v:
Veins and Lymphatics, Vol 11, Iss 1 (2022)
Background: Cerebrovascular reactivity (CVR) is a regulatory mechanism responsible for redistributing cerebral blood flow based on vasoactive stimuli and fluctuations in metabolic demand. Under normal conditions and proper functioning of the neurovas
Externí odkaz:
https://doaj.org/article/6cbae79d23bb4cc7a4270c846488311b
Autor:
Jack A. Reeves, Niels Bergsland, Michael G. Dwyer, Gregory E. Wilding, Dejan Jakimovski, Fahad Salman, Balint Sule, Nicklas Meineke, Bianca Weinstock-Guttman, Robert Zivadinov, Ferdinand Schweser
Publikováno v:
NeuroImage, Vol 261, Iss , Pp 119503- (2022)
Brain iron homeostasis is necessary for healthy brain function. MRI and histological studies have shown altered brain iron levels in the brains of patients with multiple sclerosis (MS), particularly in the deep gray matter (DGM). Previous studies wer
Externí odkaz:
https://doaj.org/article/7486bb1eb5014950863461364f0997bd
Autor:
Dejan Jakimovski, Robert Zivadinov, Bianca Weinstock-Guttman, Niels Bergsland, Michael G. Dwyer, Marcella Maria Lagana
Publikováno v:
Fluids and Barriers of the CNS, Vol 17, Iss 1, Pp 1-9 (2020)
Abstract Background Several small cross-sectional studies have investigated cerebrospinal fluid (CSF) flow dynamics in multiple sclerosis (MS) patients and have reported mixed results. Currently, there are no longitudinal studies that investigate CSF
Externí odkaz:
https://doaj.org/article/a95ddd2d73204fd8b562dbe8cd0ac132