Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Michael Freemark"'
Autor:
Grace Hendrix, Yuliya Lokhnygina, Megan Ramaker, Olga Ilkayeva, Michael Muehlbauer, William Evans, Lisa Rasbach, Robert Benjamin, Michael Freemark, Pinar Gumus Balikcioglu
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 6, Iss 6, Pp n/a-n/a (2023)
Abstract Objective Hyperglycaemia in Type 1 diabetes (T1D) results from an absolute insulin deficiency. However, insulin resistance (IR) may exacerbate glycaemic instability in T1D and contribute to long‐term cardiovascular complications. We previo
Externí odkaz:
https://doaj.org/article/0e29564d2380472bac742c9723c5c83e
Autor:
Pinar Gumus Balikcioglu, Catherine Jachthuber Trub, Metin Balikcioglu, Olga Ilkayeva, Phillip J. White, Michael Muehlbauer, James R. Bain, Sarah Armstrong, Michael Freemark
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 6, Iss 1, Pp n/a-n/a (2023)
Abstract Objectives Insulin resistance (IR) in adolescents with obesity is associated with a sex‐dependent metabolic ‘signature’ comprising the branched‐chain amino acids (BCAAs), glutamate/glutamine, C3/C5 acylcarnitines and uric acid. Here,
Externí odkaz:
https://doaj.org/article/24ad93a4efbf4bb7b0981e4b904ef0e0
Publikováno v:
Nutrients, Vol 15, Iss 18, p 4041 (2023)
The factors controlling linear growth and weight gain in the human fetus and newborn infant are poorly understood. We review here the changes in linear growth, weight gain, lean body mass, and fat mass during mid- and late gestation and the early pos
Externí odkaz:
https://doaj.org/article/eae1589a04624c14a3ab34b15b3a645b
Autor:
Lawrence P. Richer, Qiming Tan, Merlin G. Butler, Hayford M. Avedzi, Darren S. DeLorey, Ye Peng, Hein M. Tun, Arya M. Sharma, Steven Ainsley, Camila E. Orsso, Lucila Triador, Michael Freemark, Andrea M. Haqq
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 8013 (2023)
The autonomic nervous system (ANS) may play a role in the distribution of body fat and the development of obesity and its complications. Features of individuals with Prader–Willi syndrome (PWS) impacted by PWS molecular genetic classes suggest alte
Externí odkaz:
https://doaj.org/article/36b4c0505a0c40d6a759bf81b7ae41df
Autor:
Edward C. Deehan, Eloisa Colin-Ramirez, Lucila Triador, Karen L. Madsen, Carla M. Prado, Catherine J. Field, Geoff D. C. Ball, Qiming Tan, Camila Orsso, Irina Dinu, Mohammadreza Pakseresht, Daniela Rubin, Arya M. Sharma, Hein Tun, Jens Walter, Christopher B. Newgard, Michael Freemark, Eytan Wine, Andrea M. Haqq
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background Accumulating evidence suggests that the metabolic effects of metformin and fermentable fibers are mediated, in part, through diverging or overlapping effects on the composition and metabolic functions of the gut microbiome. Pre-cl
Externí odkaz:
https://doaj.org/article/1b6e7f32175043729db3148503995b54
Autor:
Pinar Gumus Balikcioglu, Megan E. Ramaker, Kelly A. Mason, Kim M. Huffman, Johanna L. Johnson, Olga Ilkayeva, Michael J. Muehlbauer, Michael Freemark, William E. Kraus
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: To provide energy for cardiopulmonary function and maintenance of blood glucose, acute aerobic exercise induces lipolysis, fatty acid oxidation (FAO), glycolysis, and glycogenolysis/gluconeogenesis. These adaptations are mediated by incre
Externí odkaz:
https://doaj.org/article/b55c841c01ab4164880faa902954b1f6
Autor:
Catherine Jachthuber Trub, Metin Balikcioglu, Michael Freemark, James Bain, Michael Muehlbauer, Olga Ilkayeva, Phillip J. White, Sarah Armstrong, Truls Østbye, Steven Grambow, Pinar Gumus Balikcioglu
Publikováno v:
Endocrinology, Diabetes & Metabolism, Vol 4, Iss 3, Pp n/a-n/a (2021)
Introduction Insulin resistance in adolescents with obesity associates with a sex‐dependent metabolic ‘signature’ comprising branched‐chain amino acids (BCAAs), glutamate and C3/C5 acylcarnitines (C3/C5), implicating altered flux through BCAA
Externí odkaz:
https://doaj.org/article/1220466addc3489db5f44f796b9e394d
Autor:
Aaloke Mody, Sarah Bartz, Christoph P Hornik, Tonny Kiyimba, James Bain, Michael Muehlbauer, Elizabeth Kiboneka, Robert Stevens, John V St Peter, Christopher B Newgard, John Bartlett, Michael Freemark
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e102233 (2014)
HIV infection occurs in 30% of children with severe acute malnutrition in sub-Saharan Africa. Effects of HIV on the pathophysiology and recovery from malnutrition are poorly understood.We conducted a prospective cohort study of 75 severely malnourish
Externí odkaz:
https://doaj.org/article/9f7c451b7fcd4c22ab943b055814dd8c
Publikováno v:
PLoS ONE, Vol 3, Iss 2, p e1535 (2008)
The lactogenic hormones prolactin (PRL) and placental lactogens (PL) play central roles in reproduction and mammary development. Their actions are mediated via binding to PRL receptor (PRLR), highly expressed in brown adipose tissue (BAT), yet their
Externí odkaz:
https://doaj.org/article/874352d1e63249049a2d228827c32786
Autor:
Pinar Gumus Balikcioglu, Catherine Jachthuber Trub, Metin Balikcioglu, Olga Ilkayeva, Phillip J. White, Michael Muehlbauer, James R. Bain, Sarah Armstrong, Michael Freemark
Publikováno v:
Endocrinology, diabetesmetabolismREFERENCES.
Insulin resistance (IR) in adolescents with obesity is associated with a sex-dependent metabolic 'signature' comprising the branched-chain amino acids (BCAAs), glutamate/glutamine, C3/C5 acylcarnitines and uric acid. Here, we compared the levels of b