Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Michael Fokuo Ofori"'
Autor:
Frederica Dedo Partey, Jasmine Naa Norkor Dowuona, Abigail Naa Adjorkor Pobee, Melanie Rose Walker, Belinda Aculley, Diana Ahu Prah, Michael Fokuo Ofori, Lea Klingenberg Barfod
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Clinical immunity to malaria develops slowly after repeated episodes of infection and antibodies are essential in naturally acquired immunity against malaria. However, chronic exposure to malaria has been linked to perturbation in B-cell hom
Externí odkaz:
https://doaj.org/article/cf3af572668d46e8a843ad71f9f8f383
Autor:
Elizabeth Obeng-Aboagye, Augustina Frimpong, Jones Amo Amponsah, Samuel E. Danso, Ewurama D. A. Owusu, Michael Fokuo Ofori
Publikováno v:
Malaria Journal, Vol 22, Iss 1, Pp 1-8 (2023)
Abstract Background Severe malaria (SM) is a fatal multi-system disease which accounted for an estimated 619,000 deaths in 2021. Less than 30% of children presenting with SM are diagnosed and treated promptly, resulting in increased mortality and neu
Externí odkaz:
https://doaj.org/article/6380e37638914f749d28fdc496985d7f
Autor:
Catherine Segbefia, Seth Kwabena Amponsah, Adwoa K. A. Afrane, Mame Yaa Nyarko, Yvonne Brew, Nihad Salifu, Samuel Yao Ahorhorlu, Abdul Malik Sulley, Lars Hviid, Michael Fokuo Ofori, George Obeng Adjei
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionLimited information exists on any interactions between hydroxyurea (HU) and antimalarials in sickle cell disease (SCD). We evaluated changes in clinical and laboratory parameters among children with SCD on HU therapy treated with artemeth
Externí odkaz:
https://doaj.org/article/fd18e68c7be749a09284410242abbfe3
Autor:
Gloria Ivy Mensah, Alahaman Nana Boakye, Anthony Basingnaa, Enid Owusu, Samuel Antwi-Baffour, Michael Fokuo Ofori, Kennedy Kwasi Addo, Dolly Jackson-Sillah, Toidi Adekambi
Publikováno v:
Immuno, Vol 1, Iss 4, Pp 400-409 (2021)
Existing tools (including GeneXpert) for diagnosis of multidrug resistant TB (MDR-TB) have limited utility when sputum samples for microbiological analyses cannot be obtained. There is the need for immunological biomarkers which could serve as putati
Externí odkaz:
https://doaj.org/article/93cc7d3e4fdf4f14b9c467623f7a6888
Autor:
Sai Sundar Rajan Raghavan, Robert Dagil, Mary Lopez-Perez, Julian Conrad, Maria Rosaria Bassi, Maria Del Pilar Quintana, Swati Choudhary, Tobias Gustavsson, Yong Wang, Pontus Gourdon, Michael Fokuo Ofori, Sebastian Boje Christensen, Daniel Thomas Remias Minja, Christentze Schmiegelow, Morten Agertoug Nielsen, Lea Barfod, Lars Hviid, Ali Salanti, Thomas Lavstsen, Kaituo Wang
Publikováno v:
PLoS Pathogens, Vol 18, Iss 11, p e1010924 (2022)
Malaria during pregnancy is a major global health problem caused by infection with Plasmodium falciparum parasites. Severe effects arise from the accumulation of infected erythrocytes in the placenta. Here, erythrocytes infected by late blood-stage p
Externí odkaz:
https://doaj.org/article/085ab7f662214893a8138336c02f4d83
Autor:
Augustina Frimpong, Michael Fokuo Ofori, Abdoelnaser M. Degoot, Kwadwo Asamoah Kusi, Buri Gershom, Jacob Quartey, Eric Kyei-Baafour, Nhi Nguyen, Wilfred Ndifon
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The changes occurring in the T cell repertoire during clinical malaria infection in children remain unknown. In this study, we undertook the first detailed comparative study of the T cell repertoire in African children with and without clinical malar
Externí odkaz:
https://doaj.org/article/c5987e916eea4374a3d23d14f7414d3e
Autor:
Henriette Hoffmann-Veltung, Nsoh Godwin Anabire, Michael Fokuo Ofori, Peter Janhmatz, Niklas Ahlborg, Lars Hviid, Maria del Pilar Quintana
Publikováno v:
eLife, Vol 11 (2022)
The issue of antibody cross-reactivity is of central importance in immunology, and not least in protective immunity to Plasmodium falciparum malaria, where key antigens show substantial allelic variation (polymorphism). However, serological analysis
Externí odkaz:
https://doaj.org/article/9e7e19c7292f4b0192ea86e0adeac26f
Autor:
Augustina Frimpong, Ewurama D. A. Owusu, Jones Amo Amponsah, Elizabeth Obeng-Aboagye, William van der Puije, Abena Fremaah Frempong, Kwadwo Asamoah Kusi, Michael Fokuo Ofori
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 12 (2022)
Sepsis defined as a dysregulated immune response is a major cause of morbidity in children. In sub-Saharan Africa, the clinical features of sepsis overlap with other frequent infections such as malaria, thus sepsis is usually misdiagnosed in the abse
Externí odkaz:
https://doaj.org/article/67e4bb423fe041cab419d4514ad52dc6
Autor:
Kwadwo Asamoah Kusi, Augustina Frimpong, Frederica Dedo Partey, Helena Lamptey, Linda Eva Amoah, Michael Fokuo Ofori
Publikováno v:
AAS Open Research, Vol 4 (2021)
Following the coronavirus outbreaks described as severe acute respiratory syndrome (SARS) in 2003 and the Middle East respiratory syndrome (MERS) in 2012, the world has again been challenged by yet another corona virus, named severe acute respiratory
Externí odkaz:
https://doaj.org/article/bddb272f71bd432b83f3eba615faae6a
Autor:
Helena Lamptey, Michael Fokuo Ofori, Bright Adu, Kwadwo Asamoah Kusi, Emmanuel Kakra Dickson, Isabella Quakyi, Michael Alifrangis
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-5 (2019)
Abstract Objective The alpha-thalassaemia trait has been associated with protection against severe malaria but its role in Plasmodium falciparum asexual parasite and gametocyte carriage remains unclear. This study examined association between prevale
Externí odkaz:
https://doaj.org/article/4c7ca9e453b4490189ff3782f84b3ed3