Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Michael Flora"'
Autor:
Xinle Cui, Zhouhong Cao, Shuishu Wang, Michael Flora, Stuart P. Adler, Michael A. McVoy, Clifford M. Snapper
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3158 (2019)
Congenital human cytomegalovirus (HCMV) infection and HCMV infection of immunosuppressed patients cause significant morbidity and mortality, and vaccine development against HCMV is a major public health priority. HCMV envelope glycoproteins gB, gH, a
Externí odkaz:
https://doaj.org/article/feccfef522c9471ba3d8a1a53b0e4655
Autor:
Gregory P. Mueller, Denes V. Agoston, Michael Flora, Donald J. Bradshaw, Peter J. Attilio, Alaa Kamnaksh
Publikováno v:
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative Medicine and Cellular Longevity, Vol 2017 (2017)
Oxidative stress and calcium excitotoxicity are hallmarks of traumatic brain injury (TBI). While these early disruptions may be corrected over a relatively short period of time, long-lasting consequences of TBI including impaired cognition and mood i
Autor:
Zhouhong Cao, Xinle Cui, Shuishu Wang, Stuart P. Adler, Michael A. McVoy, Clifford M. Snapper, Michael Flora
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3158 (2019)
International Journal of Molecular Sciences
Volume 20
Issue 13
International Journal of Molecular Sciences
Volume 20
Issue 13
Congenital human cytomegalovirus (HCMV) infection and HCMV infection of immunosuppressed patients cause significant morbidity and mortality, and vaccine development against HCMV is a major public health priority. HCMV envelope glycoproteins gB, gH, a
Autor:
Bethany Cunningham, Jayasree Krishnamurthy, Jennifer Deutsch, Lab Assistant, Michael Flora, Kenneth Lieuw
Publikováno v:
Section on Uniformed Services Program.
Objectives: 6-Mercaptopurine (6MP) is an immunosuppressive thiopurine drug used for the treatment of diseases such as inflammatory bowel disease and acute lymphocytic leukemia. 6MP is converted to thioguanine nucleotide (6TGN), which is the desired m
Autor:
Kai Xu, Lianying Yan, Christopher C. Broder, Somnath Dutta, Lin-Fa Wang, Jennifer A. Barr, Georgios Skiniotis, Yan Ru Feng, Yee Peng Chan, Min Lu, Dimitar B. Nikolov, Michael Flora
Publikováno v:
Journal of Virology. 86:11457-11471
The henipaviruses, Hendra virus (HeV) and Nipah virus (NiV), are paramyxoviruses discovered in the mid- to late 1990s that possess a broad host tropism and are known to cause severe and often fatal disease in both humans and animals. HeV and NiV infe
Autor:
Lindsey Pujanauski, Saumyaa, Raul M. Torres, Clifford M. Snapper, Jesus Colino, Michael Flora, Elaine Tuomanen
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 196(9)
Intact, inactivated Streptococcus pneumoniae [including the unencapsulated S. pneumoniae, serotype 2 strain (R36A)] markedly inhibits the humoral immune response to coimmunized heterologous proteins, a property not observed with several other intact
Publikováno v:
Biophysical Journal. 95(10):4879-4889
The opening of the Alzheimer's Abeta channel permits the flux of calcium into the cell, thus critically disturbing intracellular ion homeostasis. Peptide segments that include the characteristic histidine (His) diad, His(13) and His(14), efficiently
Autor:
Kevin Oakley, Karen Penko, Diarmuid Nicholson, Cydney Fenton, Jeffrey R. Livezey, R. Michael Tuttle, Gary L. Francis, Michael Flora, Aneeta Patel
Publikováno v:
Thyroid. 15:320-325
Mortality is low for young patients (younger than 21 years) with papillary thyroid cancer (PTC), and different mutations might contribute to this. Previous studies detected ret/PTC rearrangements more frequently in PTC from children than adults, and
Autor:
Michael Flora, James J. Mond, Andrew Lees, Gouri Chattopadhyay, Goutam Sen, Clifford M. Snapper, Dennis M. Klinman
Publikováno v:
Cellular Immunology. 232:64-74
Double- and single-stranded oligodeoxynucleotides containing unmethylated cytosine–guanosine (CpG) dinucleotides (CpGODN) activate immune cells via TLR9. In this report we synthesized hybrid DNA–RNA molecules (HDR) in order to further explore the
Autor:
Christopher C. Broder, Bryan T. Eaton, Lin-Fa Wang, Sai Kit Lam, K B Chua, Katharine N. Bossart, Michael Flora
Publikováno v:
Journal of Virology. 76:11186-11198
Nipah virus (NiV) and Hendra virus (HeV) are novel paramyxoviruses from pigs and horses, respectively, that are responsible for fatal zoonotic infections of humans. The unique genetic and biological characteristics of these emerging agents has led to