Zobrazeno 1 - 10
of 303
pro vyhledávání: '"Michael F. Olson"'
Autor:
Katerina Mardilovich, Gregory Naylor, Linda Julian, Narisa Phinichkusolchit, Karen Keeshan, Karen Blyth, Michael F. Olson
Publikováno v:
Disease Models & Mechanisms, Vol 17, Iss 5 (2024)
Externí odkaz:
https://doaj.org/article/48c60a7914734ffa8fb50ad8a03f0b2c
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/d2bcda7c3ada407d9c24bc40ad0c306e
Autor:
David J. McGarry, Giovanni Castino, Sergio Lilla, Alexandre Carnet, Loughlin Kelly, Katarina Micovic, Sara Zanivan, Michael F. Olson
Publikováno v:
Cell Reports, Vol 41, Iss 1, Pp 111442- (2022)
Summary: The MICAL1 monooxygenase is an important regulator of filamentous actin (F-actin) structures. Although MICAL1 has been shown to be regulated via protein-protein interactions at the autoinhibitory carboxyl terminus, a link between actin-regul
Externí odkaz:
https://doaj.org/article/0dc737e63c4e447d911c2e48fde6180a
Autor:
Garett Armstrong, Michael F. Olson
Publikováno v:
European Journal of Cell Biology, Vol 101, Iss 3, Pp 151257- (2022)
The role of the actin cytoskeleton during receptor-mediated endocytosis (RME) has been well characterized in yeast for many years. Only more recently has the interplay between the actin cytoskeleton and RME been extensively explored in mammalian cell
Externí odkaz:
https://doaj.org/article/c584c341c97e49298717e69bc4d89f9f
Autor:
Vanessa M. Ruscetta, Taj J. Seaton, Aleen Shakeel, Stanley N. S. Vasconcelos, Russell D. Viirre, Marc J. Adler, Michael F. Olson
Publikováno v:
Cells, Vol 12, Iss 4, p 534 (2023)
Cytoskeleton organization and dynamics are rapidly regulated by post-translational modifications of key target proteins. Acting downstream of the Cdc42 GTPase, the myotonic dystrophy-related Cdc42-binding kinases MRCKα, MRCKβ, and MRCKγ have recen
Externí odkaz:
https://doaj.org/article/d9d3e7e172be471baceb587bc7309f2f
Autor:
Michael F. Olson
Publikováno v:
Cells, Vol 12, Iss 1, p 9 (2022)
The shape and load bearing strength of cells are determined by the complex protein network comprising the actin-myosin cytoskeleton [...]
Externí odkaz:
https://doaj.org/article/78fb45b5afea4f6cbacc1de6c4d16cba
Autor:
Gregory Naylor, Linda Julian, Steven Watson-Bryce, Margaret Mullin, Robert J. Nibbs, Michael F. Olson
Publikováno v:
Cancers, Vol 14, Iss 23, p 5943 (2022)
The morphological changes during apoptosis help facilitate “immunologically silent” cell death. Caspase cleavage of the ROCK1 kinase results in its activation, which drives the forceful contraction of apoptotic cells. We previously showed that wh
Externí odkaz:
https://doaj.org/article/773f94e2af9d41baaed99d35c33aa97c
Autor:
Alessia Floerchinger, Kendelle J. Murphy, Sharissa L. Latham, Sean C. Warren, Andrew T. McCulloch, Young-Kyung Lee, Janett Stoehr, Pauline Mélénec, Cris S. Guaman, Xanthe L. Metcalf, Victoria Lee, Anaiis Zaratzian, Andrew Da Silva, Michael Tayao, Sonia Rolo, Monica Phimmachanh, Ghazal Sultani, Laura McDonald, Susan M. Mason, Nicola Ferrari, Lisa M. Ooms, Anna-Karin E. Johnsson, Heather J. Spence, Michael F. Olson, Laura M. Machesky, Owen J. Sansom, Jennifer P. Morton, Christina A. Mitchell, Michael S. Samuel, David R. Croucher, Heidi C.E. Welch, Karen Blyth, C. Elizabeth Caldon, David Herrmann, Kurt I. Anderson, Paul Timpson, Max Nobis
Publikováno v:
Cell Reports, Vol 36, Iss 11, Pp 109689- (2021)
Summary: Assessing drug response within live native tissue provides increased fidelity with regards to optimizing efficacy while minimizing off-target effects. Here, using longitudinal intravital imaging of a Rac1-Förster resonance energy transfer (
Externí odkaz:
https://doaj.org/article/60a7564e516e42fe894cc587d92fc98e
Autor:
Sipan Haikazian, Michael F. Olson
Publikováno v:
Genes, Vol 13, Iss 5, p 715 (2022)
Autosomal dominant lateral temporal epilepsy (ADLTE) is a genetic focal epilepsy associated with mutations in the LGI1, RELN, and MICAL1 genes. A previous study linking ADLTE with two MICAL1 mutations that resulted in the substitution of a highly con
Externí odkaz:
https://doaj.org/article/b97a0438e9214e8596bc67ac9c69156a
Autor:
Michael F. Olson, Joanne Edwards, Emma Shanks, Rachana Patel, Clare Orange, Lynn McGarry, Mads Gabrielsen, Katerina Mardilovich
Supplementary Figure S1: Antibody validation data, disease free progression data, and LIMK1, LIMK2 and metalloproteinase protein expression data.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::177a1ecceb6d8503fedbd75fc7d63cca
https://doi.org/10.1158/1535-7163.22501720.v1
https://doi.org/10.1158/1535-7163.22501720.v1