Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Michael F. Netter"'
Autor:
Susanne Rinné, Aytug K Kiper, Kirsty S Vowinkel, David Ramírez, Marcus Schewe, Mauricio Bedoya, Diana Aser, Isabella Gensler, Michael F Netter, Phillip J Stansfeld, Thomas Baukrowitz, Wendy Gonzalez, Niels Decher
Publikováno v:
eLife, Vol 8 (2019)
Two-pore-domain potassium (K2P) channels are key regulators of many physiological and pathophysiological processes and thus emerged as promising drug targets. As for other potassium channels, there is a lack of selective blockers, since drugs prefere
Externí odkaz:
https://doaj.org/article/9178c14d8086419a86795f2382cf020d
Autor:
Susanne, Rinné, Birgit, Stallmeyer, Alexandra, Pinggera, Michael F, Netter, Lina A, Matschke, Sven, Dittmann, Uwe, Kirchhefer, Ulrich, Neudorf, Joachim, Opp, Jörg, Striessnig, Niels, Decher, Eric, Schulze-Bahr
Publikováno v:
International journal of molecular sciences. 23(22)
Cav1.3 voltage-gated L-type calcium channels (LTCCs) are involved in cardiac pacemaking, hearing and hormone secretion, but are also expressed postsynaptically in neurons. So far, homozygous loss of function mutations in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1f72a5e5c5d63eef74d3ebe27428e2e7
https://pubmed.ncbi.nlm.nih.gov/36430690
https://pubmed.ncbi.nlm.nih.gov/36430690
Autor:
Corinna Friedrich, Susanne Rinné, Sven Zumhagen, Aytug K Kiper, Nicole Silbernagel, Michael F Netter, Birgit Stallmeyer, Eric Schulze‐Bahr, Niels Decher
Publikováno v:
EMBO Molecular Medicine, Vol 6, Iss 7, Pp 937-951 (2014)
Abstract Analyzing a patient with progressive and severe cardiac conduction disorder combined with idiopathic ventricular fibrillation (IVF), we identified a splice site mutation in the sodium channel gene SCN5A. Due to the severe phenotype, we perfo
Externí odkaz:
https://doaj.org/article/138f656725774f4ebb85eeb5736a7a6d
Autor:
Konstantin eWemhöner, Tatyana eKanyshkova, Nicole eSilbernagel, Juncal eFernandez-Orth, Stefan eBittner, Aytug K Kiper, Susanne eRinné, Michael F Netter, Sven G Meuth, Thomas eBudde, Niels eDecher
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 8 (2015)
Rats of the Wistar Albino Glaxo/Rij (WAG/Rij) strain show symptoms resembling human absence epilepsy. Thalamocortical neurons of WAG/Rij rats are characterized by an increased HCN1 expression, a negative shift in Ih activation curve, and an altered r
Externí odkaz:
https://doaj.org/article/f4e0e7c3ac26435a9350794f3ba87cb5
Autor:
Isabella Gensler, Thomas Baukrowitz, Niels Decher, Aytug K. Kiper, Phillip J. Stansfeld, Marcus Schewe, Wendy González, Diana Aser, Mauricio Bedoya, Susanne Rinné, David Ramírez, Michael F. Netter, Kirsty S Vowinkel
Publikováno v:
eLife, Vol 8 (2019)
Two-pore-domain potassium (K2P) channels are key regulators of many physiological and pathophysiological processes and thus emerged as promising drug targets. As for other potassium channels, there is a lack of selective blockers, since drugs prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a22eafb9a6fc4674d02dfc4cde212fb
https://elifesciences.org/articles/39476
https://elifesciences.org/articles/39476
Autor:
Aytug K. Kiper, Kirsty S Vowinkel, Michael F. Netter, Mauricio Bedoya, Susanne Rinné, Isabella Gensler, Phillip J. Stansfeld, Marcus Schewe, Wendy González, Thomas Baukrowitz, Diana Aser, David Ramírez, Niels Decher
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::11742f06431da8f15720aaa71a0d1828
https://doi.org/10.7554/elife.39476.023
https://doi.org/10.7554/elife.39476.023
Autor:
Susanne, Rinné, Aytug K, Kiper, Kirsty S, Vowinkel, David, Ramírez, Marcus, Schewe, Mauricio, Bedoya, Diana, Aser, Isabella, Gensler, Michael F, Netter, Phillip J, Stansfeld, Thomas, Baukrowitz, Wendy, Gonzalez, Niels, Decher
Publikováno v:
eLife
Two-pore-domain potassium (K2P) channels are key regulators of many physiological and pathophysiological processes and thus emerged as promising drug targets. As for other potassium channels, there is a lack of selective blockers, since drugs prefere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0fca79a3c383ecd62d7df914911c21d4
https://pubmed.ncbi.nlm.nih.gov/30803485
https://pubmed.ncbi.nlm.nih.gov/30803485
Autor:
Guiscard Seebohm, Niels Decher, Caroline Rolfes, Michael F. Netter, David Ramírez, Wendy González, Susanne Rinné, Aytug K. Kiper
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 467:1081-1090
Atrial fibrillation and obstructive sleep apnea are responsible for significant morbidity and mortality in the industrialized world. There is a high medical need for novel drugs against both diseases, and here, Kv1.5 channels have emerged as promisin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9e1ecd57542b3ae7521c5276e599e90
https://doi.org/10.1007/s00424-014-1665-1
https://doi.org/10.1007/s00424-014-1665-1
Autor:
Sven Zumhagen, Susanne Rinné, Nicole Silbernagel, Michael F. Netter, Birgit Stallmeyer, Aytug K. Kiper, Niels Decher, Eric Schulze-Bahr, Corinna Friedrich
Publikováno v:
EMBO Molecular Medicine
Analyzing a patient with progressive and severe cardiac conduction disorder combined with idiopathic ventricular fibrillation (IVF), we identified a splice site mutation in the sodium channel gene SCN5A. Due to the severe phenotype, we performed whol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84a3912a676746dd4fe0ddd3b3efaf72
https://doi.org/10.15252/emmm.201303783
https://doi.org/10.15252/emmm.201303783
Autor:
Nunzianna Doti, J Grohm, Amalia M. Dolga, Hans Zischka, Fabiana Perocchi, Michael F. Netter, Nikolaus Plesnila, Niels Decher, Svenja Tobaben, Carsten Culmsee, Lilja Meissner
Publikováno v:
J. Biol. Chem. 288, 10792-10804 (2013)
Small conductance calcium-activated potassium (SK2/K(Ca)2.2) channels are known to be located in the neuronal plasma membrane where they provide feedback control of NMDA receptor activity. Here, we provide evidence that SK2 channels are also located
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa1bb85d2a5762943297e1b48c67297
https://doi.org/10.1074/jbc.m113.453522
https://doi.org/10.1074/jbc.m113.453522