Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Michael F. Mouat"'
Publikováno v:
Molecular Genetics and Metabolism. 92:249-257
Lethal acrodermatitis (LAD) is a genetic disease affecting bull terrier dogs. The phenotype is similar to that for acrodermatitis enteropathica in humans, but is currently without treatment. The purpose of the research presented here is to determine
Publikováno v:
The Journal of Nutritional Biochemistry. 18:753-759
Zinc deficiency negatively affects muscle function, but there are limited biochemical data identifying the cause of this reduction in function. The objective of the present study was to identify soluble proteins in rat soleus muscle that were respons
Water maze performance and changes in serum corticosterone levels in zinc-deprived and pair-fed rats
Publikováno v:
Physiology & Behavior. 78:569-578
The aims of the present study were (1) to evaluate the learning and short- and long-term memory of zinc-deprived (ZD) and pair-fed (PF) rats in a Morris water maze (MWM) and (2) to monitor the serum corticosterone levels of these rats before and afte
Publikováno v:
The Journal of Nutritional Biochemistry. 14:74-80
The mechanism for cellular Zn uptake was investigated by depleting cell cholesterol levels, a treatment that disrupts lipid rafts/caveolae-dependent processes and inhibits coated-pit budding. Incubation of MCF-10A human breast epithelial cells with h
Autor:
Michael F. Mouat
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 32:327-337
The folding of proteins into their native structures is known to depend on molecular chaperones. However, other ligands or cofactors which still require characterisation are also likely to influence protein folding. The intention of this study was to
Publikováno v:
Biological Trace Element Research. 74:11-22
The effect of priming stromal-vascular cells in primary cultures with magnesium-deficient (MgD) media on preadipocyte differentiation was studied. Cultures were derived from dorsal subcutaneous fat tissue of young pigs and maintained 3 d in serum-fre
Autor:
Arthur Grider, Michael F. Mouat
Publikováno v:
The Journal of Nutrition. 128:1311-1314
The acrodermatitis enteropathica (AE) mutation affects zinc uptake in human fibroblasts. However, the specific biochemical lesion has not been identified. We have used the technique of two-dimensional gel electrophoresis to identify protein differenc
Autor:
Keith L. Manchester, Michael F. Mouat
Publikováno v:
Molecular and Cellular Biochemistry. 183:69-78
Eukaryotic protein synthesis initiation factor eIF-2 is usually isolated as a heterotrimer (αβγ). By use of Sephacryl S-300 fractionation an α subunit-deficient form of eIF-2 was identified in impure preparations from rabbit reticulocyte lysate a
Autor:
Mary Locniskar, Michael F. Mouat
Publikováno v:
Nutrition and Cancer. 30:108-117
An earlier study indicated that increased levels of corn oil in the diet resulted in decreased tumor yield after promotion by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate in Sencar mouse epidermis (J Leyton, ML Lee, M Locniskar, MA Belury,
Autor:
Keith L. Manchester, Michael F. Mouat
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 20:143-153
Eukaryotic protein synthesis initiation factor 2 (eIF-2), a heterotrimer, was chromatographed on high performance (Superose 6) and standard (Ultrogel AcA 34 and Sephacryl S-300) size exclusion chromatography (SEC) media. The retention volume of eIF-2