Zobrazeno 1 - 10
of 174
pro vyhledávání: '"Michael F. Hagan"'
Publikováno v:
Viruses, Vol 16, Iss 6, p 895 (2024)
This review accompanies the Special Issue on the subject of physical virology, which features work presented at the recent Gordon Research Conference (GRC) on this topic [...]
Externí odkaz:
https://doaj.org/article/7b35ba3d5e1746ae8b98080aa689c0ac
Autor:
Michael F Hagan, Farzaneh Mohajerani
Publikováno v:
PLoS Computational Biology, Vol 19, Iss 5, p e1010652 (2023)
Liquid condensate droplets with distinct compositions of proteins and nucleic acids are widespread in biological cells. While it is known that such droplets, or compartments, can regulate irreversible protein aggregation, their effect on reversible s
Externí odkaz:
https://doaj.org/article/cc7ca46a37b845cd8a48273482ceb8d3
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Systems of confined active filaments within a deformable vesicle are of relevance for development of active materials constructed from anisotropic particles. The authors propose a framework to control the transformations of the vesicle shape and fila
Externí odkaz:
https://doaj.org/article/95941c63ed69400f874eaa35b518bb5d
Autor:
Caleb A. Starr, Smita Nair, Sheng-Yuan Huang, Michael F. Hagan, Stephen C. Jacobson, Adam Zlotnick
Publikováno v:
Journal of the American Chemical Society. 145:2322-2331
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2b02fd55e7672a55862f2fa631dd7898
https://doi.org/10.1021/jacs.2c10937
https://doi.org/10.1021/jacs.2c10937
Autor:
Charlotte F. Kelley, Emily M. Messelaar, Tania L. Eskin, Shiyu Wang, Kangkang Song, Kalanit Vishnia, Agata N. Becalska, Oleg Shupliakov, Michael F. Hagan, Dganit Danino, Olga S. Sokolova, Daniela Nicastro, Avital A. Rodal
Publikováno v:
Cell Reports, Vol 13, Iss 11, Pp 2597-2609 (2015)
F-BAR domain proteins regulate and sense membrane curvature by interacting with negatively charged phospholipids and assembling into higher-order scaffolds. However, regulatory mechanisms controlling these interactions are poorly understood. Here, we
Externí odkaz:
https://doaj.org/article/f4e783064bf04fd8931e25a2b98a39f3
Autor:
Farzaneh Mohajerani, Michael F Hagan
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 7, p e1006351 (2018)
Bacterial microcompartments are large, roughly icosahedral shells that assemble around enzymes and reactants involved in certain metabolic pathways in bacteria. Motivated by microcompartment assembly, we use coarse-grained computational and theoretic
Externí odkaz:
https://doaj.org/article/a44e07b3b33a4e81b770c6f5493b3b7c
Autor:
Michael F. Hagan, Farzaneh Mohajerani
Liquid condensate droplets with distinct compositions of proteins and nucleic acids are widespread in biological cells. While it is known that such droplets, or compartments, can regulate irreversible protein aggregation, their effect on reversible s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1349f4f77648501055aa2a344accb408
https://doi.org/10.1101/2022.10.13.512015
https://doi.org/10.1101/2022.10.13.512015
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Nature Communications
Nature Communications
In active matter systems, deformable boundaries provide a mechanism to organize internal active stresses and perform work on the external environment. To study a minimal model of such a system, we perform particle-based simulations of an elastic vesi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988c0f26eefad87f226177e339f65b0e
Publikováno v:
ACS nano. 16(6)
We use computational modeling to investigate the assembly thermodynamics of a particle-based model for geometrically frustrated assembly, in which the local packing geometry of subunits is incompatible with uniform, strain-free large-scale assembly.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ba5c6e1e98c4d9b1b7ead83d80f429
https://pubmed.ncbi.nlm.nih.gov/35638478
https://pubmed.ncbi.nlm.nih.gov/35638478
Publikováno v:
ACS Nano
This article describes a theoretical and computational study of the dynamical assembly of a protein shell around a complex consisting of many cargo molecules and long flexible scaffold molecules. Our study is motivated by bacterial microcompartments,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e98ebe18c02f2ac9b4c52017ceff7367
https://doi.org/10.1021/acsnano.0c05715
https://doi.org/10.1021/acsnano.0c05715