Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michael F. Davitt"'
Autor:
Heather E. desJardins-Park, AB, Shamik Mascharak, BA, Michael Januszyk, MD, PhD, Kellen Chen, PhD, Michael F. Davitt, MD, Janos Demeter, PhD, Dominic Henn, MD, Michelle Griffin, MD, PhD, Clark A. Bonham, BA, Nancie Mooney, PhD, Ran Cheng, BS, Peter K. Jackson, PhD, Derrick C. Wan, MD, Geoffrey C. Gurtner, MD, Michael T. Longaker, MD, MBA
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 9, Iss 7S, Pp 2-3 (2021)
Purpose: Scarring in the mouse dorsal dermis is mediated by pro-fibrotic, Engrailed-1 lineage-positive fibroblasts (EPFs). We recently showed that mechanotransduction blockade (YAP inhibition, using the drug verteporfin), results in complete wound re
Externí odkaz:
https://doaj.org/article/a454e96cb6564f88b7902ecd12567506
Autor:
Heather E. desJardins-Park, AB, Katya L. Mack, PhD, Michael F. Davitt, MD, Michelle Griffin, MD, Hunter B. Fraser, PhD, Michael T. Longaker, MD, MBA, FACS
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 63-64 (2020)
Externí odkaz:
https://doaj.org/article/5d1b7dd2a1cb4a5a902dcb54cb2df11b
Autor:
Shamik Mascharak, Heather E. desJardins-Park, Mimi R. Borrelli, Alessandra L. Moore, Michael F. Davitt, Malini Chinta, Deshka S. Foster, Michael Januszyk, Sun Hyung Kwon, Gerlinde Wernig, Derrick C. Wan, H Peter Lorenz, Geoffrey C. Gurtner, MIchael T. Longaker
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 8, Iss 4S, Pp 128-129 (2020)
Externí odkaz:
https://doaj.org/article/24a845bc8d0e4b79b4a40bf0aab2f232
Autor:
Michael T. Longaker, Derrick C. Wan, Michael F. Davitt, Heather E. desJardins-Park, Geoffrey C. Gurtner, Shamik Mascharak, Nicholas Guardino
Publikováno v:
Advances in Wound Care. 11:479-495
Significance: Skin scarring poses a major biomedical burden for hundreds of millions of patients annually. However, this burden could be mitigated by therapies that promote wound regeneration, with...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cf1ae13e6dbe230d5f211fb1b807948
https://doi.org/10.1089/wound.2021.0040
https://doi.org/10.1089/wound.2021.0040
Autor:
Kellen Chen, Dharshan Sivaraj, Michael F. Davitt, Melissa C. Leeolou, Dominic Henn, Sydney R. Steele, Savana L. Huskins, Artem A. Trotsyuk, Hudson C. Kussie, Autumn H. Greco, Jagannath Padmanabhan, David P. Perrault, Alsu I. Zamaleeva, Michael T. Longaker, Geoffrey C. Gurtner
Publikováno v:
Wound Repair and Regeneration. 30:397-408
Biological scaffolds such as hydrogels provide an ideal, physio-mimetic of native extracellular matrix (ECM) that can improve wound healing outcomes after cutaneous injury. While most studies have focused on the benefits of hydrogels in accelerating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05690d927c2f1ed619213a154ecaa654
https://doi.org/10.1111/wrr.13012
https://doi.org/10.1111/wrr.13012
Autor:
Heather E. Talbott, Katya L. Mack, Michelle Griffin, Nicholas J. Guardino, Jennifer B.L. Parker, Amanda F. Spielman, Michael F. Davitt, Shamik Mascharak, Mark J. Berger, Derrick C. Wan, Hunter B. Fraser, Michael T. Longaker
SummaryIn adult mammals, skin wounds typically heal by scarring rather than through regeneration. In contrast, “super-healer” MRL mice have the unusual ability to regenerate ear punch wounds, yet the molecular basis for this regeneration remains
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::15e4b56fc8bc79cbdeaa113abf4108bf
https://doi.org/10.1101/2022.09.23.509223
https://doi.org/10.1101/2022.09.23.509223
Autor:
Derrick C. Wan, Heather E. desJardins-Park, Michael T. Longaker, Michael F. Davitt, Shamik Mascharak, Malini Chinta
Publikováno v:
Journal of Craniofacial Surgery. 31:1517-1520
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::368fd55b2fcb96e7353a5141c75613a2
https://doi.org/10.1097/scs.0000000000006602
https://doi.org/10.1097/scs.0000000000006602
Autor:
Malini Chinta, Bryan Duoto, Heather E. desJardins-Park, Mimi R. Borrelli, Kellen Chen, Sun Hyung Kwon, Derrick C. Wan, Deshka S. Foster, Michael T. Longaker, H. Peter Lorenz, Gerlinde Wernig, Geoffrey C. Gurtner, Shamik Mascharak, Michael Januszyk, Michelle Griffin, Abra H. Shen, Michael F. Davitt, Alessandra L. Moore
Publikováno v:
Science. 372
Regeneration without scarring Wounds in adult mammals typically heal by forming fibrotic scars. Mascharak et al. found that a specific population of skin fibroblasts ( Engrailed-1 lineage–negative fibroblasts) activate expression of Engrailed-1 and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8744eeca622e54c9c9070c4d6dc43f15
https://doi.org/10.1126/science.aba2374
https://doi.org/10.1126/science.aba2374
Autor:
Michael T. Longaker, Shamik Mascharak, Kellen Chen, Michelle Griffin, Deshka S. Foster, Janos Demeter, Heather E. desJardins-Park, Michael Januszyk, Derrick C. Wan, Dominic Henn, Clark A. Bonham, Nancie Mooney, Peter K. Jackson, Michael F. Davitt, Geoffrey C. Gurtner, Ran Cheng
SummaryRegeneration is the “holy grail” of tissue repair, but skin injury typically yields fibrotic, non-functional scars. Developing pro-regenerative therapies requires rigorous understanding of the molecular progression from injury to fibrosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e15735e7644481701ccdfcbecd53efa0
https://doi.org/10.1101/2020.12.17.423181
https://doi.org/10.1101/2020.12.17.423181
Autor:
Michael F. Davitt, Clark A. Bonham, Peter K. Jackson, Heather E. desJardins-Park, Shamik Mascharak, Ran Cheng, Michelle Griffin, Dominic Henn, Geoffrey C. Gurtner, Michael T. Longaker, Derrick C. Wan, Janos Demeter, Michael Januszyk, Nancie Mooney, Kellen Chen
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 9, Iss 7S, Pp 2-3 (2021)
Plastic and Reconstructive Surgery Global Open
Plastic and Reconstructive Surgery Global Open
Purpose: Scarring in the mouse dorsal dermis is mediated by pro-fibrotic, Engrailed-1 lineage-positive fibroblasts (EPFs). We recently showed that mechanotransduction blockade (YAP inhibition, using the drug verteporfin), results in complete wound re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb07aed8dea004e66221bb68657888a
http://journals.lww.com/prsgo/fulltext/10.1097/01.GOX.0000769936.79898.fc
http://journals.lww.com/prsgo/fulltext/10.1097/01.GOX.0000769936.79898.fc