Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Michael F. Coleman"'
Autor:
Michael F. Coleman, Eylem Kulkoyluoglu Cotul, Alexander J. Pfeil, Emily N. Devericks, Muhammad H. Safdar, Marvis Monteiro, Hao Chen, Alyssa N. Ho, Numair Attaar, Hannah M. Malian, Violet A. Kiesel, Alexis Ramos, Matthew Smith, Heena Panchal, Adam Mailloux, Dorothy Teegarden, Stephen D. Hursting, Michael K. Wendt
Publikováno v:
Breast Cancer Research, Vol 26, Iss 1, Pp 1-20 (2024)
Abstract Background Metabolic plasticity mediates breast cancer survival, growth, and immune evasion during metastasis. However, how tumor cell metabolism is influenced by and feeds back to regulate breast cancer progression are not fully understood.
Externí odkaz:
https://doaj.org/article/4bc52c528bb64c7f812b584380877b6e
Autor:
Kristina K. Camp, Michael F. Coleman, Tori L. McFarlane, Steven S. Doerstling, Subreen A. Khatib, Erika T. Rezeli, Alfor G. Lewis, Alexander J. Pfeil, Laura A. Smith, Laura W. Bowers, Farnaz Fouladi, Weida Gong, Elaine M. Glenny, Joel S. Parker, Ginger L. Milne, Ian M. Carroll, Anthony A. Fodor, Randy J. Seeley, Stephen D. Hursting
Publikováno v:
JCI Insight, Vol 8, Iss 19 (2023)
Obesity promotes triple-negative breast cancer (TNBC), and effective interventions are urgently needed to break the obesity-TNBC link. Epidemiologic studies indicate that bariatric surgery reduces TNBC risk, while evidence is limited or conflicted fo
Externí odkaz:
https://doaj.org/article/eb847aa873194d0fb917c72cb1aa7ccd
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Every cancer genome is unique, resulting in potentially near infinite cancer cell phenotypes and an inability to predict clinical outcomes in most cases. Despite this profound genomic heterogeneity, many cancer types and subtypes display a non-random
Externí odkaz:
https://doaj.org/article/4ca83b39aba34351bf682af1398ec6e7
Autor:
Laura A. Smith, Dalton M. Craven, Magdalena A. Rainey, Alyssa J. Cozzo, Meredith S. Carson, Elaine M. Glenny, Nishita Sheth, Shannon B. McDonell, Erika T. Rezeli, Stephanie A. Montgomery, Laura W. Bowers, Michael F. Coleman, Stephen D. Hursting
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
IntroductionAdvanced age and obesity are independent risk and progression factors for triple negative breast cancer (TNBC), which presents significant public health concerns for the aging population and its increasing burden of obesity. Due to parall
Externí odkaz:
https://doaj.org/article/d64cde964e82441388b949a28f6acbea
Autor:
Violet A. Kiesel, Madeline P. Sheeley, Michael F. Coleman, Eylem Kulkoyluoglu Cotul, Shawn S. Donkin, Stephen D. Hursting, Michael K. Wendt, Dorothy Teegarden
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-13 (2021)
Abstract Pyruvate carboxylase (PC) is a mitochondrial enzyme that catalyzes the ATP-dependent carboxylation of pyruvate to oxaloacetate (OAA), serving to replenish the tricarboxylic acid (TCA) cycle. In nonmalignant tissue, PC plays an essential role
Externí odkaz:
https://doaj.org/article/b686bcf2126847f6852b5d69aa73e389
Autor:
Alyssa J. Cozzo, Michael F. Coleman, Jane B. Pearce, Alexander J. Pfeil, Suhas K. Etigunta, Stephen D. Hursting
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cancer cells experience unique and dynamic shifts in their metabolic function in order to survive, proliferate, and evade growth inhibition in the resource-scarce tumor microenvironment. Therefore, identification of pharmacological agents with potent
Externí odkaz:
https://doaj.org/article/2ac4f3f3b8f14dae888fa5086ffff01e
Autor:
Michael F. Coleman, Ciara H. O’Flanagan, Alexander J. Pfeil, Xuewen Chen, Jane B. Pearce, Susan Sumner, Sergey A. Krupenko, Stephen D. Hursting
Publikováno v:
Nutrients, Vol 13, Iss 5, p 1637 (2021)
Background: Triple-negative breast cancers (TNBCs), accounting for approximately 15% of breast cancers, lack targeted therapy. A hallmark of cancer is metabolic reprogramming, with one-carbon metabolism essential to many processes altered in tumor ce
Externí odkaz:
https://doaj.org/article/5e62c6a63a4747168323fdaaca50b6b1
Autor:
Che-Pei Kung, Meghan B Skiba, Erika J Crosby, Jessica Gorzelitz, Mary A Kennedy, Bethany A Kerr, Yun Rose Li, Sarah Nash, Melanie Potiaumpai, Amber S Kleckner, Dara L James, Michael F Coleman, Ciaran M Fairman, Gloria C Galván, David O Garcia, Max J Gordon, Mathilde His, Lyndsey M Hornbuckle, So-Youn Kim, Tae-Hyung Kim, Amanika Kumar, Mélanie Mahé, Karen K McDonnell, Jade Moore, Sangphil Oh, Xinghui Sun, Melinda L Irwin
Publikováno v:
JNCI Monographs. 2023:149-157
The overall goal of the annual Transdisciplinary Research in Energetics and Cancer (TREC) Training Workshop is to provide transdisciplinary training for scientists in energetics and cancer and clinical care. The 2022 Workshop included 27 early-to-mid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cff50f7b8c915ad6f9d5af497bd8e41
https://doi.org/10.1093/jncimonographs/lgad005
https://doi.org/10.1093/jncimonographs/lgad005
Autor:
Faiza Kalam, Dara L James, Yun Rose Li, Michael F Coleman, Violet A Kiesel, Elizabeth M Cespedes Feliciano, Stephen D Hursting, Dorothy D Sears, Amber S Kleckner
Publikováno v:
JNCI Monographs. 2023:84-103
Intermittent fasting entails restricting food intake during specific times of day, days of the week, religious practice, or surrounding clinically important events. Herein, the metabolic and circadian rhythm mechanisms underlying the proposed benefit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57188a060d0ca96add2a96c58bf3c150
https://doi.org/10.1093/jncimonographs/lgad008
https://doi.org/10.1093/jncimonographs/lgad008
Autor:
Michael F Coleman, Kristina K Camp, Tori L McFarlane, Steven S Doerstling, Subreen A Khatib, Erika T Rezeli, Alfor G Lewis, Alex J Pfeil, Laura A Smith, Laura W Bowers, Farnaz Fouladi, Weida Gong, Elaine M Glenny, Joel S Parker, Ginger L Milne, Ian M Carroll, Anthony A Fodor, Randy J Seeley, Stephen D Hursting
Obesity promotes triple-negative breast cancer (TNBC), and effective interventions are urgently needed to break the obesity-TNBC link. Epidemiologic studies indicate that bariatric surgery reduces TNBC risk, while evidence is limited or conflicted fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8accbd6ca33dc60a91ca287911fc2a4
https://doi.org/10.1101/2023.05.19.541484
https://doi.org/10.1101/2023.05.19.541484
