Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Michael F. Borgerding"'
Publikováno v:
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals. 23(7)
Alternations in gene methylation and other epigenetic changes regulate normal development as well as drive disease progression. The aim of this study is to investigate global methylation changes in the buccal cells of smokers and smokeless tobacco us
Autor:
Elaine K. Round, Leanne R. Campbell, Mitchell F. Stiles, Michael F. Borgerding, Michael Dixon
Publikováno v:
Beiträge zur Tabakforschung International, Vol 26, Iss 6, Pp 242-260 (2015)
Une série d'études cliniques ambulatoires furent menées en vue d'évaluer les variations des biomarqueurs d'exposition au tabac et de l'appréciation subjective des produits lorsque des fumeurs adultes passent à une consommation combinée compos
Autor:
Bobbette A. Jones, Kristin M. Marano, Buddy G. Brown, Steven J. Kathman, Brian Keith Nordskog, Michael F. Borgerding
Publikováno v:
Inhalation Toxicology
Cardiovascular disease (CVD) biomarkers of biological effect (BoBE), including hematologic biomarkers, serum lipid-related biomarkers, other serum BoBE, and one physiological biomarker, were evaluated in adult cigarette smokers (SMK), smokeless tobac
Autor:
Buddy G. Brown, Michael F. Borgerding, Brian Keith Nordskog, Kristin M. Marano, Bobbette A. Jones, Leanne R. Campell
Publikováno v:
Inhalation Toxicology
An age-stratified, cross-sectional study was conducted in the US among healthy adult male cigarette smokers, moist snuff consumers, and non-tobacco consumers to evaluate cardiovascular biomarkers of biological effect (BoBE). Physiological assessments
Publikováno v:
Nicotine & Tobacco Research. 16:1336-1347
INTRODUCTION The objectives of this trial were to investigate short-term changes in product usage, tobacco-related biomarkers of exposure, and subjective effects in smokers who switched to dissolvable tobacco (Camel Orbs) use. METHODS Participants we
Publikováno v:
Beiträge zur Tabakforschung International, Vol 25, Iss 5, Pp 550-562 (2013)
Among the more than 5000 chemicals reported in cigarette smoke condensate (CSC), heterocyclic aromatic amines (HAAs) are considered to be a contributor to observed biological activity. HAAs are non-volatile and are reported at ppb levels in CSC. A ne
Publikováno v:
Regulatory Toxicology and Pharmacology. 64:367-387
Selected toxicant concentrations and other chemical measures have been determined for 43 U.S. smokeless tobacco products sold in 2006 and 2007. Products evaluated included moist snuff, dry snuff, loose leaf, plug, dissolvable and snus tobacco brands.
Autor:
Kristin M, Marano, Ziad S, Naufal, Steven J, Kathman, Joy A, Bodnar, Michael F, Borgerding, Charles D, Garner, Cody L, Wilson
Publikováno v:
Regulatory Toxicology and Pharmacology. 64:243-252
To investigate whether cadmium has an independent role in diseases associated with tobacco consumption, epidemiology data were reviewed, biomonitoring data were analyzed, and probabilistic risk assessment (PRA) was performed. Results from previous ep
Autor:
Joy A. Bodnar, Jianxin Yu, William Monroe Coleman, Michael F. Borgerding, Larry T. Taylor, Shiu-Hang Yip, Mehdi Ashraf-Khorassani
Publikováno v:
Beiträge zur Tabakforschung International, Vol 24, Iss 2, Pp 48-57 (2010)
L'ampleur de la degradation du melange de glycerol dans une cigarette en train de se consumer pour former de l'acroleine et de l'acetone a ete quantifiee par l'addition de glycerol- 13 C 3 aux trois sortes de cigarettes d'une marque leader sur le mar
Publikováno v:
Journal of Chromatographic Science. 48:194-199
A new direct method using liquid chromatography-tandem mass spectrometry has been developed and validated for quantitation of 3-hydroxypropylmercapturic acid (3-HPMA) in urine. The method is fast, simple, and does not require extraction from urine. A