Zobrazeno 1 - 10
of 378
pro vyhledávání: '"Michael F. Seldin"'
Autor:
You Li, Zhiqiang Li, Ruiling Chen, Min Lian, Hanxiao Wang, Yiran Wei, Zhengrui You, Jun Zhang, Bo Li, Yikang Li, Bingyuan Huang, Yong Chen, Qiaoyan Liu, Zhuwan Lyu, Xueying Liang, Qi Miao, Xiao Xiao, Qixia Wang, Jingyuan Fang, YongYong Shi, Xiangdong Liu, Michael F. Seldin, M. Eric Gershwin, Ruqi Tang, Xiong Ma
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Primary biliary cholangitis is a rare, chronic immune-mediated liver disease triggered by environmental exposures in genetically susceptible individuals. Here, the authors investigate the functional mechanism underlying the association of 19p13.3 var
Externí odkaz:
https://doaj.org/article/c3bffe3f09684055a2d88786709182d8
Autor:
Jinyoung Byun, Younghun Han, Ivan P. Gorlov, Jonathan A. Busam, Michael F. Seldin, Christopher I. Amos
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-12 (2017)
Abstract Background Accurate inference of genetic ancestry is of fundamental interest to many biomedical, forensic, and anthropological research areas. Genetic ancestry memberships may relate to genetic disease risks. In a genome association study, f
Externí odkaz:
https://doaj.org/article/fe004f89ced448e2bca4a0c0c715f6ca
Autor:
Evaggelia Liaskou, Louisa Jeffery, Dimitrios Chanouzas, Blagoje Soskic, Michael F. Seldin, Lorraine Harper, David Sansom, Gideon M. Hirschfield
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract The CD28 locus is associated with susceptibility to a variety of autoimmune and immune-mediated inflammatory diseases including primary sclerosing cholangitis (PSC). Previously, we linked the CD28 pathway in PSC disease pathology and found t
Externí odkaz:
https://doaj.org/article/e5a9b051286947d2a6faeaf9453b110f
Autor:
Carl D. Langefeld, Hannah C. Ainsworth, Deborah S. Cunninghame Graham, Jennifer A. Kelly, Mary E. Comeau, Miranda C. Marion, Timothy D. Howard, Paula S. Ramos, Jennifer A. Croker, David L. Morris, Johanna K. Sandling, Jonas Carlsson Almlöf, Eduardo M. Acevedo-Vásquez, Graciela S. Alarcón, Alejandra M. Babini, Vicente Baca, Anders A. Bengtsson, Guillermo A. Berbotto, Marc Bijl, Elizabeth E. Brown, Hermine I. Brunner, Mario H. Cardiel, Luis Catoggio, Ricard Cervera, Jorge M. Cucho-Venegas, Solbritt Rantapää Dahlqvist, Sandra D’Alfonso, Berta Martins Da Silva, Iñigo de la Rúa Figueroa, Andrea Doria, Jeffrey C. Edberg, Emőke Endreffy, Jorge A. Esquivel-Valerio, Paul R. Fortin, Barry I. Freedman, Johan Frostegård, Mercedes A. García, Ignacio García de la Torre, Gary S. Gilkeson, Dafna D. Gladman, Iva Gunnarsson, Joel M. Guthridge, Jennifer L. Huggins, Judith A. James, Cees G. M. Kallenberg, Diane L. Kamen, David R. Karp, Kenneth M. Kaufman, Leah C. Kottyan, László Kovács, Helle Laustrup, Bernard R. Lauwerys, Quan-Zhen Li, Marco A. Maradiaga-Ceceña, Javier Martín, Joseph M. McCune, David R. McWilliams, Joan T. Merrill, Pedro Miranda, José F. Moctezuma, Swapan K. Nath, Timothy B. Niewold, Lorena Orozco, Norberto Ortego-Centeno, Michelle Petri, Christian A. Pineau, Bernardo A. Pons-Estel, Janet Pope, Prithvi Raj, Rosalind Ramsey-Goldman, John D. Reveille, Laurie P. Russell, José M. Sabio, Carlos A. Aguilar-Salinas, Hugo R. Scherbarth, Raffaella Scorza, Michael F. Seldin, Christopher Sjöwall, Elisabet Svenungsson, Susan D. Thompson, Sergio M. A. Toloza, Lennart Truedsson, Teresa Tusié-Luna, Carlos Vasconcelos, Luis M. Vilá, Daniel J. Wallace, Michael H. Weisman, Joan E. Wither, Tushar Bhangale, Jorge R. Oksenberg, John D. Rioux, Peter K. Gregersen, Ann-Christine Syvänen, Lars Rönnblom, Lindsey A. Criswell, Chaim O. Jacob, Kathy L. Sivils, Betty P. Tsao, Laura E. Schanberg, Timothy W. Behrens, Earl D. Silverman, Marta E. Alarcón-Riquelme, Robert P. Kimberly, John B. Harley, Edward K. Wakeland, Robert R. Graham, Patrick M. Gaffney, Timothy J. Vyse
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-18 (2017)
Systemic lupus erythematosus (SLE) is an autoimmune disease with a strong ethnic and gender bias. In a transancestral genetic association study, Langefeldet al. identify 24 novel regions associated with risk to lupus and propose a cumulative hits hyp
Externí odkaz:
https://doaj.org/article/a68227bc3ba0457486591e4743061bf9
Autor:
Fang Qiu, Ruqi Tang, Xianbo Zuo, Xingjuan Shi, Yiran Wei, Xiaodong Zheng, Yaping Dai, Yuhua Gong, Lan Wang, Ping Xu, Xiang Zhu, Jian Wu, Chongxu Han, Yueqiu Gao, Kui Zhang, Yuzhang Jiang, Jianbo Zhou, Youlin Shao, Zhigang Hu, Ye Tian, Haiyan Zhang, Na Dai, Lei Liu, Xudong Wu, Weifeng Zhao, Xiaomin Zhang, Zhidong Zang, Jinshan Nie, Weihao Sun, Yi Zhao, Yuan Mao, Po Jiang, Hualiang Ji, Qing Dong, Junming Li, Zhenzhong Li, Xinli Bai, Li Li, Maosong Lin, Ming Dong, Jinxin Li, Ping Zhu, Chan Wang, Yanqiu Zhang, Peng Jiang, Yujue Wang, Rohil Jawed, Jing Xu, Yu Zhang, Qixia Wang, Yue Yang, Fan Yang, Min Lian, Xiang Jiang, Xiao Xiao, Yanmei Li, Jingyuan Fang, Dekai Qiu, Zhen Zhu, Hong Qiu, Jianqiong Zhang, Wenyan Tian, Sufang Chen, Ling Jiang, Bing Ji, Ping Li, Guochang Chen, Tianxue Wu, Yan Sun, Jianjiang Yu, Huijun Tang, Michun He, Min Xia, Hao Pei, Lihua Huang, Zhuye Qing, Jianfang Wu, Qinghai Huang, Junhai Han, Wei Xie, Zhongsheng Sun, Jian Guo, Gengsheng He, M. Eric Gershwin, Zhexiong Lian, Xiang Liu, Michael F. Seldin, Xiangdong Liu, Weichang Chen, Xiong Ma
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-8 (2017)
Primary biliary cholangitis is an autoimmune liver disease. Here, the authors show that variants in interleukin genes which potentially deregulate their expression are associated with this condition, and suggest that the IL21 signalling pathway may h
Externí odkaz:
https://doaj.org/article/2d9f1e41b1654d168ba642000f183a48
Autor:
Christopher I. Amos, John K. Wiencke, Ann G. Schwartz, Margaret R. Wrensch, Paige M. Bracci, Laura J. Bierut, Michael F. Seldin, Marsha L. Frazier, Wei Chen, Stacy M. Lloyd, Chongjuan Wei, Jennette D. Sison, Angela S. Wenzlaff, Emily Y. Lu, Huifeng Zhang, Margaret R. Spitz, Xifeng Wu, Helen M. Hansen, Ivan P. Gorlov, Kyle M. Walsh
PDF file - 926K, Triangle plot showing estimated admixture in the African-American case-control population. Estimates were performed using 102 AIMs and data from the International HapMap Project on 167 Yoruban African (Green dots), 165 European (Red
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a10fdc7ca424295b08285fd3271d94df
https://doi.org/10.1158/1055-9965.22436478
https://doi.org/10.1158/1055-9965.22436478
Autor:
Douglas F. Easton, Jacques Simard, Stephen J. Chanock, Georgia Chenevix-Trench, Paul D.P. Pharoah, Antonis C. Antoniou, Daniela Seminara, Elizabeth Gillanders, Michael F. Seldin, Rosalind A. Eeles, Ulrike Peters, Ali Amin Al Olama, Jonathan Marchini, Rayjean J. Hung, Laura Ottini, Rita Schmutzler, Mads Thomassen, Kenneth Offit, Sue K. Park, John K. Field, Jack A. Taylor, Christopher K. Edlund, Tameka Shelford, Stephanie L. Schmit, Sylvie Laboissiere, Andrew Berchuck, Sune F. Nielsen, Marc T. Goodman, Deborah J. Thompson, Yongyong Shi, Hongbing Shen, Tracy A. O'Mara, Marjorie Riggan, Paul Brennan, Linda E. Kelemen, Sara Benlloch, Catherine M. Phelan, James D. McKay, Marcia Adams, Sara Lindström, Liesel FitzGerald, Peter Kraft, Zsofia Kote-Jarai, Katja Butterbach, Julie M. Cunningham, Judith Manz, Penny Soucy, Karoline Kuchenbaecker, Andrew Lee, Lesley McGuffog, Hua Ling, Belynda D. Hicks, Irene Brüske-Hohlfeld, Melanie Waldenberger, Angela Risch, Heike Bickeböller, David V. Conti, Graham G. Giles, Judith L. Forman, Fergus J. Couch, David E. Goldgar, Stephen Demetriades, Stefanie Nelson, David J. Van Den Berg, François Bacot, Daniel Vincent, Daniel Tessier, Craig Luccarini, Ahsan Kamal, Christopher A. Haiman, Charlisse Caga-Anan, Stig E. Bojesen, Dennis J. Hazelett, Gerhard A. Coetzee, Elizabeth Pugh, Jane Romm, Xiangjun Xiao, Yafang Li, Amanda B. Spurdle, Kimberly Doheny, Laura Fachal, Kyriaki Michailidou, Alison M. Dunning, Stephen B. Gruber, Thomas A. Sellers, David J. Hunter, Graham Casey, Simon A. Gayther, Fredrick R. Schumacher, Jinyoung Byun, Zhaoming Wang, Joe Dennis, Christopher I. Amos
Supplementary Methods and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c056dd71739c15089af8c5ffe07532
https://doi.org/10.1158/1055-9965.22436431.v1
https://doi.org/10.1158/1055-9965.22436431.v1
Autor:
Christopher I. Amos, John K. Wiencke, Ann G. Schwartz, Margaret R. Wrensch, Paige M. Bracci, Laura J. Bierut, Michael F. Seldin, Marsha L. Frazier, Wei Chen, Stacy M. Lloyd, Chongjuan Wei, Jennette D. Sison, Angela S. Wenzlaff, Emily Y. Lu, Huifeng Zhang, Margaret R. Spitz, Xifeng Wu, Helen M. Hansen, Ivan P. Gorlov, Kyle M. Walsh
PDF file - 67K, Imputed SNP associations from the case-control analysis of lung cancer (by histology) in African-Americans (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647445c966c88cd2a983bbde7af9180e
https://doi.org/10.1158/1055-9965.22436466.v1
https://doi.org/10.1158/1055-9965.22436466.v1
Autor:
Christopher I. Amos, John K. Wiencke, Ann G. Schwartz, Margaret R. Wrensch, Paige M. Bracci, Laura J. Bierut, Michael F. Seldin, Marsha L. Frazier, Wei Chen, Stacy M. Lloyd, Chongjuan Wei, Jennette D. Sison, Angela S. Wenzlaff, Emily Y. Lu, Huifeng Zhang, Margaret R. Spitz, Xifeng Wu, Helen M. Hansen, Ivan P. Gorlov, Kyle M. Walsh
PDF file - 561K, Association of SNPs on chromosome 15q25.1 with lung cancer, with and without adjustment for missense variant rs16969968. Black circles depict association of SNPs with lung cancer, adjusted for sex, age, study site, % African ancestry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bd75b632858c5599681bfa954295dd
https://doi.org/10.1158/1055-9965.22436475
https://doi.org/10.1158/1055-9965.22436475
Autor:
Christopher I. Amos, John K. Wiencke, Ann G. Schwartz, Margaret R. Wrensch, Paige M. Bracci, Laura J. Bierut, Michael F. Seldin, Marsha L. Frazier, Wei Chen, Stacy M. Lloyd, Chongjuan Wei, Jennette D. Sison, Angela S. Wenzlaff, Emily Y. Lu, Huifeng Zhang, Margaret R. Spitz, Xifeng Wu, Helen M. Hansen, Ivan P. Gorlov, Kyle M. Walsh
Background: Genome-wide association studies of European and East Asian populations have identified lung cancer susceptibility loci on chromosomes 5p15.33, 6p22.1-p21.31, and 15q25.1. We investigated whether these regions contain lung cancer susceptib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2161c91b5434b85340cd2f1b99868a54
https://doi.org/10.1158/1055-9965.c.6515415
https://doi.org/10.1158/1055-9965.c.6515415