Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Michael Fährmann"'
Autor:
Michael Fährmann
Publikováno v:
Current Medicinal Chemistry. 15:1175-1191
Protein kinase C (PKC) family members are multifunctional kinases that have been implicated in many cell biological and physiological tasks including acid, pepsinogen, and mucous production. Through the use of small-molecule PKC modulators, PKC has b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc557512541b7f1d07f46c83f47d00bb
https://doi.org/10.2174/092986708784310413
https://doi.org/10.2174/092986708784310413
Autor:
Marc–André Kaufhold, Nikolaj Klöcker, Michael Manns, Anja Krabbenhöft, Penghong Song, Michael Fährmann, W. Beil, Susan J. Hagen, Regina Engelhardt, Brigitte Riederer, Ursula Seidler
Publikováno v:
Gastroenterology. 134:1058-1069
Background & Aims: K + recycling at the apical membrane of gastric parietal cells is a prerequisite for gastric acid secretion. Two K + channels are currently being considered for this function, namely KCNQ1 and inwardly rectifying K + channels (Kir)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2656a147f39298ef0d2ca1c37629543
https://doi.org/10.1053/j.gastro.2008.01.033
https://doi.org/10.1053/j.gastro.2008.01.033
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1783(2):214-223
Induction of apoptosis by the PP1/PP2A inhibitor calyculin A was inhibited if the CaMKII inhibitor KN-93 was added no later than 10 min after addition of calyculin A. The physiological relevance and mechanism of CaMKII during apoptosis, however, rema
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16776e023d0e2cbe0d64479ad81ed172
Publikováno v:
British Journal of Pharmacology. 139:545-554
The phorbolester 12-O-tetradecanoyl phorbol-13-acetate (TPA), an activator of protein kinase C (PKC), inhibits cholinergic stimulation of gastric acid secretion. We observed that this effect strongly correlated with the inhibition of Ca2+/calmodulin-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::232e4c2e9e9836343ac84ef1ce1cb586
https://doi.org/10.1038/sj.bjp.0705211
https://doi.org/10.1038/sj.bjp.0705211
Autor:
Michael Fährmann, Sandra Braak
Publikováno v:
Archives of Insect Biochemistry and Physiology. 52:155-162
The Ca2+/calmodulin-dependent kinase CaMKII is a key signaling component in Ca2+-dependent physiological processes. The expression and function of CaMKII in insect brain is well documented but less investigated for other tissues of insects. The prese
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d94213633ec1d146e1afdcadcf5fdf3
https://doi.org/10.1002/arch.10077
https://doi.org/10.1002/arch.10077
Publikováno v:
British Journal of Pharmacology. 136:938-946
1. The phorbol ester TPA, an activator of protein kinase C (PKC), inhibits cholinergic stimulation of gastric acid secretion but increases basal H(+) secretion. 2. Since these contradictory findings suggest the action of different PKC isozymes we ana
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85924080239858e1eafdf61f022a2494
https://doi.org/10.1038/sj.bjp.0704790
https://doi.org/10.1038/sj.bjp.0704790
Publikováno v:
Cellular Signalling. 14:161-168
The Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) is thought to be activated during the cholinergic stimulation of gastric acid secretion. The carbachol-induced acid production of cultured rabbit parietal cells was dose-dependently inhibited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24b6ea3a7bc98f414b5d9acd704f7731
https://doi.org/10.1016/s0898-6568(01)00231-5
https://doi.org/10.1016/s0898-6568(01)00231-5
Binding of CaMKII to the giant muscle protein projectin: stimulation of CaMKII activity by projectin
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1569:127-134
Projectin is an integral high molecular mass protein of insect flight muscle binding to myosin and paramyosin. Yet, the role of projectin in insect flight muscle is not well understood. In this study we provide evidence for the interaction of project
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8557c7590d352ebbbc79592346d2647f
https://doi.org/10.1016/s0304-4165(01)00251-3
https://doi.org/10.1016/s0304-4165(01)00251-3
Autor:
Michael Fährmann, Andreas Pfeiffer
Publikováno v:
Archives of Biochemistry and Biophysics. 380:151-158
Gastric acid secretion is conveyed by different signal transduction pathways, among these being the muscarinic receptor M(3)-mediated acid secretion. There is some evidence that CaMkinase II is involved in the acetylcholine-conveyed acid release. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d60c342bf813f25556d2f5bef422d263
https://doi.org/10.1006/abbi.2000.1910
https://doi.org/10.1006/abbi.2000.1910
Autor:
Matthias Möhlig, Andreas Pfeiffer, M. Osterhoff, Ursula Seidler, Michael Fährmann, Petra Jacob
Publikováno v:
European Journal of Biochemistry. 266:1036-1042
Ca2+/calmodulin-dependent protein kinase II is thought to participate in M3 muscarinic receptor-mediated acid secretion in gastric parietal cells. During acid secretion tubulovesicles carrying H+/K+-ATPase fuse with the apical membrane. We localized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b549d2bd18599caa2ed07e3d97650bae
https://doi.org/10.1046/j.1432-1327.1999.00959.x
https://doi.org/10.1046/j.1432-1327.1999.00959.x