Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Michael F, Jackson"'
Autor:
Noushin Ahmadpour, Meher Kantroo, Michael J. Stobart, Jessica Meza-Resillas, Shahin Shabanipour, Jesus Parra-Nuñez, Tetiana Salamovska, Anna Muzaleva, Finnegan O’Hara, Dustin Erickson, Bruno Di Gaetano, Sofia Carrion-Falgarona, Bruno Weber, Alana Lamont, Natalie E. Lavine, Tiina M. Kauppinen, Michael F. Jackson, Jillian L. Stobart
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Astrocytes express ionotropic receptors, including N-methyl-D-aspartate receptors (NMDARs). However, the contribution of NMDARs to astrocyte-neuron interactions, particularly in vivo, has not been elucidated. Here we show that a knockdown ap
Externí odkaz:
https://doaj.org/article/a8ce933929184bcfa3f5b6c95d1aad63
Autor:
Shreya H Dhume, Steven A Connor, Fergil Mills, Parisa Karimi Tari, Sarah HM Au-Yeung, Benjamin Karimi, Shinichiro Oku, Reiko T Roppongi, Hiroshi Kawabe, Shernaz X Bamji, Yu Tian Wang, Nils Brose, Michael F Jackson, Ann Marie Craig, Tabrez J Siddiqui
Publikováno v:
eLife, Vol 11 (2022)
LRRTMs are postsynaptic cell adhesion proteins that have region-restricted expression in the brain. To determine their role in the molecular organization of synapses in vivo, we studied synapse development and plasticity in hippocampal neuronal circu
Externí odkaz:
https://doaj.org/article/34f1f7432bce4e58b14dc493955892e7
Autor:
Chetan S. Patil, Hongbin Li, Natalie E. Lavine, Ruoyang Shi, Ankur Bodalia, Tabrez J. Siddiqui, Michael F. Jackson
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Pannexin-1 (Panx1) is a large-pore ion and solute permeable channel highly expressed in the nervous system, where it subserves diverse processes, including neurite outgrowth, dendritic spine formation, and N-methyl D-aspartate (NMDA) receptor (NMDAR)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bb3d100b1a4775a798367cbeec68e97
https://doi.org/10.1073/pnas.2112870119
https://doi.org/10.1073/pnas.2112870119
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 2, Pp 3003-3024 (2014)
G Protein Coupled Receptors (GPCRs) are the largest family of receptors whose ligands constitute nearly a third of prescription drugs in the market. They are widely involved in diverse physiological functions including learning and memory. NMDA recep
Externí odkaz:
https://doaj.org/article/05c567833ba147b4a257b180aa81ec58
Autor:
Gilbert J. Kirouac, Samuel Booth, Shreya H. Dhume, Jeremy W. Chopek, Prabhisha Silwal, Nazmeena Zahra, Michael F. Jackson, Tabrez J. Siddiqui, Nirmala Padmanabhan, Ji Hyun Ko, Dali Zhang, Benyamin Karimi
Publikováno v:
Molecular Psychiatry. 26:6912-6925
Reduced activity of the mediodorsal thalamus (MD) and abnormal functional connectivity of the MD with the prefrontal cortex (PFC) cause cognitive deficits in schizophrenia. However, the molecular basis of MD hypofunction in schizophrenia is not known
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::216d54c6e34e978e14760422a2d202e4
https://doi.org/10.1038/s41380-021-01146-6
https://doi.org/10.1038/s41380-021-01146-6
Autor:
Samar Sayedyahossein, David W. Litchfield, Rafael E Sanchez-Pupo, Chetan S. Patil, Michael F. Jackson, Silvia Penuela, Rebecca Lau, Daniel Nouri-Nejad, Brooke L. O’Donnell, Kristina Jurcic, Danielle Johnston, Gregory B. Gloor, Laszlo Gyenis
Publikováno v:
Molecular Biology of the Cell
Pannexin 1 (PANX1) is a glycoprotein that forms large pore channels capable of passing ions and metabolites such as ATP for cellular communication. PANX1 has been implicated in many diseases including breast cancer and melanoma, where inhibition or d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7a6a5407f369776719cfce9ece69190
http://europepmc.org/articles/PMC8098850
http://europepmc.org/articles/PMC8098850
Autor:
Shreya H Dhume, Steven A Connor, Fergil Mills, Parisa Karimi Tari, Sarah HM Au-Yeung, Benjamin Karimi, Shinichiro Oku, Reiko T Roppongi, Hiroshi Kawabe, Shernaz X Bamji, Yu Tian Wang, Nils Brose, Michael F Jackson, Ann Marie Craig, Tabrez J Siddiqui
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d1d6ca4bdff359b135067d7dad08bcc8
https://doi.org/10.7554/elife.64742.sa2
https://doi.org/10.7554/elife.64742.sa2
Publikováno v:
Neural Plasticity, Vol 2016 (2016)
Synaptic plasticity refers to the ability of neurons to strengthen or weaken synaptic efficacy in response to activity and is the basis for learning and memory. Glial cells communicate with neurons and in this way contribute in part to plasticity in
Externí odkaz:
https://doaj.org/article/529aebe7311c45fdbb08a627f1f45a73
Autor:
Gilbert J. Kirouac, Ji Hyun Ko, Christopher M. Anderson, Lingling Lu, Michael F. Jackson, Dali Zhang, Samuel Booth, Abdullah Ramadan
Publikováno v:
Movement Disorders
Background Levodopa (l-dopa) is the frontline treatment for motor symptoms of Parkinson's disease. However, prolonged use of l-dopa results in a motor complication known as levodopa-induced dyskinesia (LID) in ~50% of patients over 5 years. Objective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3950a015e460198e18b6fce6fe5ad4f1
https://doi.org/10.1002/mds.28357
https://doi.org/10.1002/mds.28357
Publikováno v:
Journal of Neurochemistry. 154:468-485
Pannexin-1 (Panx1) is a large pore membrane channel with unique conduction properties ranging from non-selective ion permeability to the extracellular release of signalling molecules. The release of ATP by Panx1 has been particularly well-characteriz
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89e03c9cfb870918f47a12078444a055
https://doi.org/10.1111/jnc.15004
https://doi.org/10.1111/jnc.15004