Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Michael F, Gallagher"'
Autor:
Mark Bates, Cathy D Spillane, Michael F Gallagher, Amanda McCann, Cara Martin, Gordon Blackshields, Helen Keegan, Luke Gubbins, Robert Brooks, Doug Brooks, Stavros Selemidis, Sharon O'Toole, John J O'Leary
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243715 (2020)
Despite the use of front-line anticancer drugs such as paclitaxel for ovarian cancer treatment, mortality rates have remained almost unchanged for the past three decades and the majority of patients will develop recurrent chemoresistant disease which
Externí odkaz:
https://doaj.org/article/1b4173fb417c4b46a697ca0c7cfb267a
Autor:
Charles J d'Adhemar, Cathy D Spillane, Michael F Gallagher, Mark Bates, Katie M Costello, Jacqui Barry-O'Crowley, Kathryn Haley, Niamh Kernan, Ciara Murphy, Paul C Smyth, Ken O'Byrne, Stephen Pennington, Aoife A Cooke, Brendan Ffrench, Cara M Martin, Dearbhaile O'Donnell, Bryan Hennessy, Britta Stordal, Stephen Finn, Amanda McCann, Noreen Gleeson, Tom D'Arcy, Brian Flood, Luke A J O'Neill, Orla Sheils, Sharon O'Toole, John J O'Leary
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100816 (2014)
The prognosis of epithelial ovarian cancer is poor in part due to the high frequency of chemoresistance. Recent evidence points to the Toll-like receptor-4 (TLR4), and particularly its adaptor protein MyD88, as one potential mediator of this resistan
Externí odkaz:
https://doaj.org/article/208a05f77739491a8afed939f68cee69
Autor:
Brendan, Ffrench, Claudia, Gasch, Karsten, Hokamp, Cathy, Spillane, Gordon, Blackshields, Thamir Mahmoud, Mahgoub, Mark, Bates, Louise, Kehoe, Aoibhinn, Mooney, Ronan, Doyle, Brendan, Doyle, Dearbhaile, O'Donnell, Noreen, Gleeson, Bryan T, Hennessy, Britta, Stordal, Ciaran, O'Riain, Helen, Lambkin, Sharon, O'Toole, John J, O'Leary, Michael F, Gallagher
Publikováno v:
Cell Death & Disease
It is long established that tumour-initiating cancer stem cells (CSCs) possess chemoresistant properties. However, little is known of the mechanisms involved, particularly with respect to the organisation of CSCs as stem-progenitor-differentiated cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a7c0a2692867afe93b67865ee3af566
https://pubmed.ncbi.nlm.nih.gov/29048400
https://pubmed.ncbi.nlm.nih.gov/29048400
Autor:
Claudia Gasch, Cathy Spillane, John J. O'Leary, Salah A Elbaruni, Sharon O'Toole, Victoria McEneaney, Olayemi Azeez Abdullai, Gomaa Sulaiman, Ronan Knittel, Helen Keegan, Brendan Doyle, Charles d’Adhemar, Kevin O’Connor, Eric L. Campbell, Desmond G. Higgins, Paul N. Moynagh, Aoife A. Cooke, Gordon Blackshields, Brendan Ffrench, Annamarie Rogers, Luke A. J. O'Neill, Mathia Yc Lee, Michael F Gallagher, Mark Bates, Ian B. Jeffery
Publikováno v:
Cell death and differentiation. 24(11)
We have previously reported that myeloid differentiation primary response gene 88 (MyD88) is downregulated during all-trans retinoic acid (RA)-induced differentiation of pluripotent NTera2 human embryonal carcinoma cells (hECCs), whereas its maintain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::181be9f2d828cd9f53b4c92b61555279
https://pubmed.ncbi.nlm.nih.gov/28885616
https://pubmed.ncbi.nlm.nih.gov/28885616
Autor:
Orla Sheils, Amanda McCann, Lynda McEvoy, Michael F Gallagher, Noreen Gleeson, John J. O'Leary, Britta K. Stordal, Lucy A. Norris, Cathy D Spillane, Sharon O'Toole, Fiona Furlong, Cara Martin, Aloysius McGoldrick
Publikováno v:
Laboratory Investigation. 93:523-552
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27f8301fc9ea856718e507554b9e00ba
https://doi.org/10.1038/labinvest.2013.39
https://doi.org/10.1038/labinvest.2013.39
Publikováno v:
Journal of rehabilitation medicine. 49(1)
Objective To consider the effect of active lung volume recruitment ("air stacking") on rate of decline in vital capacity. Design Retrospective cross-sectional design. Patients People with Duchenne muscular dystrophy. Methods Vital capacity was measur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e006cac6f7f3a4dcaa008b4feb7e4f3
https://pubmed.ncbi.nlm.nih.gov/27630091
https://pubmed.ncbi.nlm.nih.gov/27630091
Autor:
Alexandros Laios, Kai Q Lao, Salah A Elbaruni, Michael F Gallagher, Yvonne M Salley, Cara Martin, K Denning, Richard Flavin, Paul Smyth, Sebastian Vencken, John J. O'Leary, Sinead T Aherne, Sharon O'Toole, J Li, Jamie McInerney, Mathia Yc Lee, Orla Sheils
Publikováno v:
Journal of Ovarian Research
Journal of Ovarian Research, Vol 2, Iss 1, p 19 (2009)
Journal of Ovarian Research, Vol 2, Iss 1, p 19 (2009)
Background Tumours with high proportions of differentiated cells are considered to be of a lower grade to those containing high proportions of undifferentiated cells. This property may be linked to the differentiation properties of stem cell-like pop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a27882ad0083091febf7dfe71a5dfed6
https://doi.org/10.1186/1757-2215-2-19
https://doi.org/10.1186/1757-2215-2-19
Autor:
Susan Heavey, Michael F Gallagher, John J. O'Leary, Becky A.S. Bibby, Stephen G. Maher, Brendan Ffrench, Niamh Lynam-Lennon, John V. Reynolds, Claudia Gasch, Gary Sommerville, Jennifer J. Quinn
Publikováno v:
Oncotarget
Resistance to neoadjuvant chemoradiation therapy (CRT) remains a critical barrier to the effective treatment of esophageal adenocarcinoma (EAC). Cancer stem-like cells (CSCs) are a distinct subpopulation of cells implicated in the resistance of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d21007a55f7bd927a433bd46be4d70fd
https://pubmed.ncbi.nlm.nih.gov/28002789
https://pubmed.ncbi.nlm.nih.gov/28002789
Autor:
Michael F Gallagher, Paul Smyth, Yvonne M Salley, John J. O'Leary, Cathy D Spillane, Gordon Blacksheilds, William Watson, Brendan Ffrench, Cara Martin, Orla Sheils, Salah El Baruni
Publikováno v:
Journal of clinical pathology. 68(9)
AimsTargeting the stem cell properties of tumor-initiating cells is an avenue through which cancer treatment may be improved. Before this can be achieved, so-called ‘cancer stem cell’ (CSC) models must be developed and characterized in specific m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::085a25e33b21aea91dfc22ffb9a42614
https://pubmed.ncbi.nlm.nih.gov/26038242
https://pubmed.ncbi.nlm.nih.gov/26038242
Autor:
Bryce K. Allen, Donat Alpar, Viren Amin, Fazila Asmar, Nagi G. Ayad, Anne-Marie Baird, Louise J. Barber, Becky A.S. Bibby, Emma Bolderson, Philippe Bouvet, Frédéric Catez, Leandro Cerchietti, Snehajyoti Chatterjee, Taiping Chen, Andreas I. Constantinou, Stuart J. Conway, Dashyant Dhanak, Jean-Jacques Diaz, Marc Diederich, Xinmin Fan, Brendan Ffrench, Michael F. Gallagher, Marco Gerlinger, Steven D. Gore, Steven G. Gray, Kirsten Grønbæk, David S. Hewings, Holger Heyn, Zhe Jin, Stephanie Kaypee, Yutaka Kondo, Tapas K. Kundu, Florian Laforêts, Matthew W. Lawless, Stephen G. Maher, Somnath Mandal, Virginie Marcel, Aleksandar Milosavljevic, Hannah L. Moody, Atsushi Natsume, Thomas B. Nicholson, Kenneth J. O’Byrne, Shane O’Grady, John J. O’Leary, Fumiharu Ohka, Vitor Onuchic, Vineet Pande, Clara Penas, Li-Xia Peng, Benet Pera, Antoinette Sabrina Perry, Olga Piskareva, Chara A. Pitta, David J. Pocalyko, Thomas Prebet, Chao-Nan Qian, Glen Reid, Derek J. Richard, Timothy P.C. Rooney, Michael Schnekenburger, Alexandra Søgaard, Peter Staller, Raymond L. Stallings, Vasileios Stathias, Gabriel Therizols, Nicolas Veland, Casey M. Wright, Xiaojing Zhang, Wei Zhu, Jiaqi Qian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72dd990a6c8ae573244de2d41706a718
https://doi.org/10.1016/b978-0-12-800206-3.00033-1
https://doi.org/10.1016/b978-0-12-800206-3.00033-1