Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Michael E. Woodman"'
Autor:
Joey P Ting, Frances Tung, Stephen Antonysamy, Stephen Wasserman, Spencer B Jones, Feiyu F Zhang, Alfonso Espada, Howard Broughton, Michael J Chalmers, Michael E Woodman, Holly A Bina, Jeffrey A Dodge, Jordi Benach, Aiping Zhang, Christopher Groshong, Danalyn Manglicmot, Marijane Russell, Sepideh Afshar
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190850 (2018)
To date, IL-17A antibodies remain the only therapeutic approach to correct the abnormal activation of the IL-17A/IL-17R signaling complex. Why is it that despite the remarkable success of IL-17 antibodies, there is no small molecule antagonist of IL-
Externí odkaz:
https://doaj.org/article/9c2e01bb6db44b01a1e0d014dd80e53b
Autor:
Warren B Rouse, Ryan J Andrews, Nicholas J Booher, Jibo Wang, Michael E Woodman, Ernst R Dow, Theodore C Jessop, Walter N Moss
Publikováno v:
NAR Genomics and Bioinformatics
In recent years, interest in RNA secondary structure has exploded due to its implications in almost all biological functions and its newly appreciated capacity as a therapeutic agent/target. This surge of interest has driven the development and adapt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08d878f4bdc3acff8c1a4a426a5e9912
https://pubmed.ncbi.nlm.nih.gov/35047817
https://pubmed.ncbi.nlm.nih.gov/35047817
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52276 (2012)
Burkholderia pseudomallei is the causative agent of melioidosis and is a major mediator of sepsis in its endemic areas. Because of the low LD(50) via aerosols and resistance to multiple antibiotics, it is considered a Tier 1 select agent by the CDC a
Externí odkaz:
https://doaj.org/article/50852ab4b1be4178ba8f2f2a5026c9fd
Publikováno v:
PLoS ONE, Vol 5, Iss 7, p e11445 (2010)
B cells are typically characterized as positive regulators of the immune response, primarily by producing antibodies. However, recent studies indicate that various subsets of B cells can perform regulatory functions mainly through IL-10 secretion. He
Externí odkaz:
https://doaj.org/article/e1d9d7335a0a486bb409b84335d05a08
Publikováno v:
Current Protocols in Microbiology
This protocol describes an efficient method for screening intact bacteria for the presence of desired DNA sequences using the polymerase chain reaction (PCR). This method is commonly referred to as colony PCR. © 2016 by John Wiley & Sons, Inc.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f4ab2b210d651b0e21ecd7def135112
https://doi.org/10.1002/cpmc.14
https://doi.org/10.1002/cpmc.14
Autor:
Michael E. Woodman, Frances Tung, Danalyn Manglicmot, Stephen I. Wasserman, Joey P. Ting, Stephen Antonysamy, Jeffrey Alan Dodge, Marijane Russell, Aiping Zhang, Michael J. Chalmers, Spencer B. Jones, Feiyu F. Zhang, Sepideh Afshar, Howard B. Broughton, Jordi Benach, Holly A. Bina, Christopher Groshong, Alfonso Espada
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190850 (2018)
PLoS ONE
PLoS ONE
To date, IL-17A antibodies remain the only therapeutic approach to correct the abnormal activation of the IL-17A/IL-17R signaling complex. Why is it that despite the remarkable success of IL-17 antibodies, there is no small molecule antagonist of IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5060023139b115836157f31caf092353
https://doi.org/10.1371/journal.pone.0190850
https://doi.org/10.1371/journal.pone.0190850
Autor:
Sean P. Riley, Tomasz Bykowski, Anne E. Cooley, Catherine A. Brissette, Brian Stevenson, Logan H. Burns, Ashutosh Verma, Michael E. Woodman
Publikováno v:
International Journal of Medical Microbiology. 298:257-267
Lyme borreliae naturally maintain numerous distinct DNA elements of the cp32 family, each of which carries a mono- or bicistronic erp locus. The encoded Erp proteins are surface-exposed outer membrane lipoproteins that are produced at high levels dur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3ccfadbcbede770973d67fdf5b26630
https://doi.org/10.1016/j.ijmm.2007.09.004
https://doi.org/10.1016/j.ijmm.2007.09.004
Autor:
Brian Stevenson, Michael E. Woodman, Catherine A. Brissette, Tomasz Bykowski, Anne E. Cooley, Reinhard Wallich, Volker Brade, Peter Kraiczy
Publikováno v:
Infection and Immunity. 75:4227-4236
The Lyme disease spirochete,Borrelia burgdorferi, is largely resistant to being killed by its hosts’ alternative complement activation pathway. One possible resistance mechanism of these bacteria is to coat their surfaces with host complement regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a4c3f3ef1a349c15484b7292129fe8
https://doi.org/10.1128/iai.00604-07
https://doi.org/10.1128/iai.00604-07
Autor:
Brian Stevenson, Michael E. Woodman, John J. Lazarus, Kathryn Tucker, R. Mark Wooten, Jens Hellwage, Marina Botto, Tomasz Bykowski, Anne E. Cooley, Jennifer C. Miller
Publikováno v:
Infection and Immunity. 75:3131-3139
The causative agent of Lyme disease,Borrelia burgdorferi, is naturally resistant to its host's alternative pathway of complement-mediated killing. Several different borrelial outer surface proteins have been identified as being able to bind host fact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528f07aa9ec5a20ab1ca9dc1ae4fc1fa
https://doi.org/10.1128/iai.01923-06
https://doi.org/10.1128/iai.01923-06
Publikováno v:
Microbial Pathogenesis. 41:43-47
A novel, infectious Borrelia burgdorferi that expresses green fluorescent protein (GFP) was developed to examine the utility of this marker protein to label live bacteria during infection processes. Use of a borrelial erpAB promoter to direct gfp tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6bbaf2d7e02f6c7cd455b7ce443172c
https://doi.org/10.1016/j.micpath.2006.04.004
https://doi.org/10.1016/j.micpath.2006.04.004