Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Michael E. Stockton"'
Autor:
Yu Guo, Minjie Shen, Qiping Dong, Natasha M. Méndez-Albelo, Sabrina X. Huang, Carissa L. Sirois, Jonathan Le, Meng Li, Ezra D. Jarzembowski, Keegan A. Schoeller, Michael E. Stockton, Vanessa L. Horner, André M. M. Sousa, Yu Gao, Birth Defects Research Laboratory, Jon E. Levine, Daifeng Wang, Qiang Chang, Xinyu Zhao
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-23 (2023)
Abstract Fragile X messenger ribonucleoprotein 1 protein (FMRP) binds many mRNA targets in the brain. The contribution of these targets to fragile X syndrome (FXS) and related autism spectrum disorder (ASD) remains unclear. Here, we show that FMRP de
Externí odkaz:
https://doaj.org/article/c712033063bc4873a8e01bd8ebf89faa
Autor:
Ethan G. Hughes, Michael E. Stockton
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In the central nervous system, oligodendrocytes produce myelin sheaths that enwrap neuronal axons to provide trophic support and increase conduction velocity. New oligodendrocytes are produced throughout life through a process referred to as oligoden
Externí odkaz:
https://doaj.org/article/00298fba70d54edfb05c2063fbad0193
Autor:
Yue Li, Michael E. Stockton, Brian E. Eisinger, Yinghua Zhao, Jessica L. Miller, Ismat Bhuiyan, Yu Gao, Zhiping Wu, Junmin Peng, Xinyu Zhao
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Loss of fragile X mental retardation protein (FMRP) leads to fragile X syndrome, associated with cognitive dysfunction. Here the authors show that mice lacking FMRP show reduced hippocampal neurogenesis and cognitive deficits, which can be rescued by
Externí odkaz:
https://doaj.org/article/26fc57d7c2ad436ca758e946a648f712
Autor:
Daifeng Wang, Carissa L Sirois, Chen Zhou, Minjie Shen, Yu Gao, Keegan A Schoeller, Jonathan Le, Qian-Quan Sun, Tomer Korabelnikov, Xinyu Zhao, Qiping Dong, Meng Li, Qiang Chang, Michael E. Stockton, Sudharsan Kannan, Yu Guo
Publikováno v:
Molecular psychiatry
Parvalbumin interneurons (PVIs) are affected in many psychiatric disorders including schizophrenia (SCZ), however the mechanism remains unclear. FXR1, a high confident risk gene for SCZ, is indispensable but its role in the brain is largely unknown.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c5e819d4d08000f162af684033aa6a
https://doi.org/10.1038/s41380-021-01096-z
https://doi.org/10.1038/s41380-021-01096-z
Autor:
Michael E. Stockton, Gregory L. Futia, Karl Kilborn, Emily A. Gibson, Michael A. Thornton, Ethan G. Hughes, Baris N. Ozbay, Diego Restrepo
Publikováno v:
Neurophotonics. 9
SignificanceThree-photon (3P) microscopy significantly increases the depth and resolution of in vivo imaging due to decreased scattering and nonlinear optical sectioning. Simultaneous excitation of multiple fluorescent proteins is essential to study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5381ca0bbdd6b5bdf4f2a06f2f2165
https://doi.org/10.1117/1.nph.9.3.031912
https://doi.org/10.1117/1.nph.9.3.031912
Autor:
Michael A, Thornton, Gregory L, Futia, Michael E, Stockton, Baris N, Ozbay, Karl, Kilborn, Diego, Restrepo, Emily A, Gibson, Ethan G, Hughes
Publikováno v:
Neurophotonics. 9(3)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::814d3bb4e0d50e17ddb6afdb294cdc23
https://pubmed.ncbi.nlm.nih.gov/35496497
https://pubmed.ncbi.nlm.nih.gov/35496497
Autor:
Junmin Peng, Jessica L. Miller, Zhiping Wu, Yu Gao, Brian E. Eisinger, Yinghua Zhao, Xinyu Zhao, Yue Li, Ismat Bhuiyan, Michael E. Stockton
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-16 (2018)
Nature Communications
Nature Communications
Fragile X syndrome (FXS) is the most prevalent inherited intellectual disability, resulting from a loss of fragile X mental retardation protein (FMRP). Patients with FXS suffer lifelong cognitive disabilities, but the function of FMRP in the adult br
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25b9a04e5ccae3e63fb310778ea1f09f
http://link.springer.com/article/10.1038/s41467-018-04869-3
http://link.springer.com/article/10.1038/s41467-018-04869-3
Publikováno v:
Neurobiol Learn Mem
Neurodevelopmental disorders result from impaired development or maturation of the central nervous system. Both genetic and environmental factors can contribute to the pathogenesis of these disorders; however, the exact causes are frequently complex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6aa0d325a8ba1dd3df6e9b76329e57e
https://europepmc.org/articles/PMC6461531/
https://europepmc.org/articles/PMC6461531/
Autor:
Minjie Shen, Dianhua Qiao, Jonathan Loi, Jared Carlson-Stevermer, Pamela J. McLean, So Yeon Koo, Andrew J. Petersen, Mathew V. Jones, Marion Delenclos, Subhojit Roy, Lina Wang, Jichao Sun, Utpal Das, Xinyu Zhao, Amanda M. Snead, Andrew Sproul, Michael E. Stockton, Krishanu Saha, Anita Bhattacharyya
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
CRISPR/Cas9 guided gene-editing is a potential therapeutic tool, however application to neurodegenerative disease models has been limited. Moreover, conventional mutation correction by gene-editing would only be relevant for the small fraction of neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3ace6c9faac8fabf1f60cd30767e0f4
https://pubmed.ncbi.nlm.nih.gov/30604771
https://pubmed.ncbi.nlm.nih.gov/30604771
Autor:
Minjie Shen, Jon Loi, Jared Carlson-Stevermer, Jichao Sun, Subhojit Roy, Marion Delenclos, Andrew J. Petersen, Mathew V. Jones, Xinyu Zhao, Lina Wang, Anita Bhattacharyya, Michael E. Stockton, Krishanu Saha, Pamela J. McLean, Utpal Das
Publikováno v:
Alzheimer's & Dementia. 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e80eb6b394f174fdb616e1a345490049
https://doi.org/10.1016/j.jalz.2018.06.3019
https://doi.org/10.1016/j.jalz.2018.06.3019