Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Michael E. Murphy"'
Autor:
Conor D. Tweed, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Lerato Mohapi, Michael E. Murphy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Stephen H. Gillespie
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We investigated the incidence of adverse events and cure rates according to H
Externí odkaz:
https://doaj.org/article/d4f6503cd6b943dbb18e73105c9b0eb8
Autor:
Conor D. Tweed, Angela M. Crook, Evans I. Amukoye, Rodney Dawson, Andreas H. Diacon, Madeline Hanekom, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Michael E. Murphy, Saraswathi E. Murthy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Genevieve H. Wills, Stephen H. Gillespie
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The incidence and severity of tuberculosis chemotherapy toxicity is poorly characterised. We used data available from patients in the REMoxTB trial to provide an assessment of the risks associated with the standard regimen and two
Externí odkaz:
https://doaj.org/article/87ffe9cc14bf494197dd9d05a700110f
Autor:
Conor Duncan Tweed, Genevieve Helen Wills, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Cheryl E. Louw, Timothy D. McHugh, Carl Mendel, Sarah Meredith, Lerato Mohapi, Michael E. Murphy, Stephen Murray, Sara Murthy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha Singh, M. Spigelman, S. H. Gillespie
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial to describe the incidence of predisposing factors and the natural history in patients with liver
Externí odkaz:
https://doaj.org/article/9c5b8d40012f497db02bc3f9607be6f2
Autor:
Michael E. Murphy, Patrick P. J. Phillips, Carl M. Mendel, Emily Bongard, Anna L. C. Bateson, Robert Hunt, Saraswathi Murthy, Kasha P. Singh, Michael Brown, Angela M. Crook, Andrew J. Nunn, Sarah K. Meredith, Marc Lipman, Timothy D. McHugh, Stephen H. Gillespie, On behalf of the REMoxTB Consortium
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background The use of early morning sputum samples (EMS) to diagnose tuberculosis (TB) can result in treatment delay given the need for the patient to return to the clinic with the EMS, increasing the chance of patients being lost during the
Externí odkaz:
https://doaj.org/article/6ed07cb9f278456d91f517953c95470c
Autor:
Kordo Saeed, Nusreen Ahmad-Saeed, Rachel Annett, Gavin Barlow, Lucinda Barrett, Sara E. Boyd, Nicola Boran, Peter Davies, Harriet Hughes, Gwennan Jones, Laura Leach, Maureen Lynch, Deepa Nayar, Robert J. Maloney, Martin Marsh, Olivia Milburn, Shanine Mitchell, Lynn Moffat, Luke S. P. Moore, Michael E. Murphy, Shaan Ashk O’Shea, Fionnuala O’Sullivan, Teresa Peach, Christina Petridou, Niamh Reidy, Mathyruban Selvaratnam, Ben Talbot, Vanessa Taylor, Deborah Wearmouth, Catherine Aldridge
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases. 42:169-176
Septic arthritis is a serious condition with significant morbidity and mortality, routinely diagnosed using culture. The FDA has recently approved the rapid molecular BioFire® Joint Infection Panel (BJIP) for synovial fluid. We aimed to evaluate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d34133fe17a5bc6d19063d1ce2feb1b
https://doi.org/10.1007/s10096-022-04538-w
https://doi.org/10.1007/s10096-022-04538-w
Autor:
Perrine Lasserre, Banushan Balansethupathy, Vincent J. Vezza, Adrian Butterworth, Alexander Macdonald, Ewen O. Blair, Liam McAteer, Stuart Hannah, Andrew C. Ward, Paul A. Hoskisson, Alistair Longmuir, Steven Setford, Eoghan C. W. Farmer, Michael E. Murphy, Harriet Flynn, Damion K. Corrigan
Publikováno v:
Analytical Chemistry
SARS-CoV-2 diagnostic practices broadly involve either quantitative polymerase chain reaction (qPCR)-based nucleic amplification of viral sequences or antigen-based tests such as lateral flow assays (LFAs). Reverse transcriptase-qPCR can detect viral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::331f140b14ec3f51c4020e9954065571
https://doi.org/10.1021/acs.analchem.1c04456
https://doi.org/10.1021/acs.analchem.1c04456
Autor:
Eoghan C. W. Farmer, Stuart Hannah, Steven Setford, Michael E. Murphy, Alexander MacDonald, Ewen O. Blair, Harriet Flynn, Andrew C. Ward, Paul A. Hoskisson, Adrian Butterworth, Banushan Balansethupathy, Alistair Longmuir, Damion K. Corrigan, Perrine Lasserre, Liam McAteer, Vincent Vezza
SARS-CoV-2 diagnostic practices broadly involve either qPCR based nucleic amplification or lateral flow assays (LFAs). qPCR based techniques suffer from the disadvantage of requiring thermal cycling (difficult to implement for low-cost field use) lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::769273276ce5d54a3a24089567e35661
https://doi.org/10.26434/chemrxiv-2021-08vx4
https://doi.org/10.26434/chemrxiv-2021-08vx4
Autor:
Eoghan C. W. Farmer, Ewen O. Blair, Vincent Vezza, Alexander MacDonald, Paul A. Hoskisson, Alistair Longmuir, Michael E. Murphy, Stuart Hannah, Damion K. Corrigan, Steven Setford, Christopher Rinaldi, Andrew C. Ward, Adrian Butterworth, Perrine Lasserre
Publikováno v:
Chemical communications (Cambridge, England). 57(30)
Accurate and rapid diagnostic tests are critical to reducing the impact of SARS-CoV-2. This study presents early, but promising measurements of SARS-CoV-2 using the ACE2 enzyme as the recognition element to achieve clinically relevant detection. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3760eada59aea1fbe66f2b8e920d3a0
https://pubmed.ncbi.nlm.nih.gov/33729260
https://pubmed.ncbi.nlm.nih.gov/33729260
Autor:
Jessie Howell, William J. Peveler, Michael E. Murphy, Carl S. Goodyear, Jennifer Gracie, Tansy C. Hammarton, Simon Pybus, Mohammad Saiful Islam Sajib, Colin Graham, J. Kenneth Baillie, Melanie Jimenez, Gill Thomson, Taya Forde, Andrew G. Farthing, Alice Garrett
The immune system plays a crucial role in maintaining a healthy body by working around the clock to recognize and respond to infection. Inflammation is part of the immune system’s protective response to an infection. The inflammatory response is in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d40a870145f502cd4d622fdd50428d
https://eprints.gla.ac.uk/242310/1/242310.pdf
https://eprints.gla.ac.uk/242310/1/242310.pdf
Autor:
Steven Setford, Christopher Rinaldi, Alexander MacDonald, Michael E. Murphy, Andrew C. Ward, Adrian Butterworth, Vincent Vezza, Alistair Longmuir, Ewen O. Blair, Damion K. Corrigan, Paul A. Hoskisson, Stuart Hannah, Perrine Lasserre
Emerging in late 2019, the SARS-CoV-2 virus has had a devastating health and economic effects around the world forcing governments to enact restrictions on day to day life, resulting in severe economic and social disruption. The virus has stimulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b4aaef1ab46834b31682855d1b9d059
https://doi.org/10.26434/chemrxiv.13416272
https://doi.org/10.26434/chemrxiv.13416272