Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Michael E. Kamarck"'
Autor:
Kathryn M. Bausch, Gary Davis, Gerhard König, Paul Fracasso, Michael E. Kamarck, Dana O. Wirak, David Wunderlich, Carla M. Brini, Robert N. Dreyer, Paul P. Tamburini, Thomas M. Buckholz, Lisa J. Hammond
Publikováno v:
European Journal of Biochemistry. 224:265-271
A major pre-beta-amyloid protein695 (APP695) processing activity from Alzheimer's disease brain extracts was identified and found to be indistinguishable from the activity of cathepsin D.APP695 processing activity cleaved APP695 into a series of frag
Autor:
Michael E Kamarck
Publikováno v:
Nature biotechnology. 24(5)
Biopharmaceutical manufacturing capacity has moved through three discrete chapters in its 25-year history. Could the next chapter herald formal manufacturing-capacity sharing among companies?
Autor:
S. Heald, Robert N. Dreyer, Paul P. Tamburini, Michael E. Kamarck, Richard Bayney, Axel Unterbeck, Alice Lee, Lisa J. Hammond, Robert F. Tilton, Gary Davis, Ramabhadran Triprayar
Publikováno v:
Biochemistry. 30(43)
Certain precursor proteins (APP751 and APP770) of the amyloid beta-protein (AP) present in Alzheimer's disease contain a Kunitz-type serine protease inhibitor domain (APPI). In this study, the domain is obtained as a functional inhibitor through both
Autor:
Robert N. Dreyer, Jutta Hansen, Robert D. Dally, Jack Letsinger, Heeja Dr. Yoo-Warren, Paul P. Tamburini, Michael E. Kamarck, Jim Elting, Rudolf Dr Hanko, David G. Osterman, Ann Gore-Willse
Publikováno v:
Analytical biochemistry. 186(2)
A rapid sensitive method for the quantification of in vitro HIV-protease activity has been developed on the basis of the endoproteolytic conversion of N -Dns-SQNYPIV to N -Dns-SQNY. The use of the N -dansyl group as a fluorescence label was shown to
Autor:
Michael E. Kamarck, Paul D. Gottlieb
Publikováno v:
The Journal of Immunology. 119:407-415
Cell proliferation and surface alloantigen expression were monitored during development of the fetal mouse thymus in vivo from day 13 of gestation until birth, and in organ cultures established at day 13 of gestation. Expression of Thy-1, Ly-1, Ly-2,
Autor:
Jeffrey M. Greve, Carla P. Forte, Ann M. Meyer, Alan Mcclelland, Susan Connolly Yost, Michael E. Kamarck, Gary Davis, Christopher W. Marlor
Publikováno v:
Cell. 56:839-847
The major human rhinovirus receptor has been identified with monoclonal antibodies that inhibit rhinovirus infection. These monoclonal antibodies recognize a 95 kd cell surface glycoprotein on human cells and on mouse transfectants expressing a rhino
Autor:
Douglas A. Austen, James Elting, Scott J. Goebel, Thomas R. Barnett, John Hart, Michael E. Kamarck, Axel Kretschmer
Publikováno v:
The Journal of Cell Biology
The recent cloning of complete cDNAs encoding carcinoembryonic antigen (CEA) and non-specific cross-reacting antigen has revealed the existence of a new gene family belonging to the immunoglobulin gene superfamily. We have reported the isolation of a
Publikováno v:
Somatic Cell Genetics. 8:385-402
We have examined the cell surface expression of the human histocompatibility antigens HLA-A, B, C and beta 2-microglobulin (beta 2m) on a human-mouse somatic cell hybrid line. Using specific antibodies and the fluorescence-activated cell sorter (FACS
Autor:
Frank H. Ruddle, Martin E. Hemler, Jack L. Strominger, Michael E. Kamarck, Pamela G. Messer Peters
Publikováno v:
The Journal of Experimental Medicine
The genes that code for the human lymphocyte cell surface determinants defined by monoclonal antibodies A- 1A5 and A- 3A4 have been genetically mapped. All human chromosomes, except Y, were included in a series of human less than mouse lymphocyte hyb
Publikováno v:
Journal of Immunological Methods. 62:39-47
Genetic mapping of differentiation specific surface antigens has been hampered by difficulty in preparation of interspecies hybrid cells which continue to express differentiated functions. A method has been developed for production of interspecies T