Zobrazeno 1 - 10
of 208
pro vyhledávání: '"Michael E. Hochberg"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
Abstract Bacteria release and sense small molecules called autoinducers in a process known as quorum sensing. The prevailing interpretation of quorum sensing is that by sensing autoinducer concentrations, bacteria estimate population density to regul
Externí odkaz:
https://doaj.org/article/fa11762994d141988c43e6290a5ab5c6
Autor:
Daniel Promislow, Rozalyn M. Anderson, Marten Scheffer, Bernard Crespi, James DeGregori, Kelley Harris, Barbara Natterson Horowitz, Morgan E. Levine, Maria A. Riolo, David S. Schneider, Sabrina L. Spencer, Dario Riccardo Valenzano, Michael E. Hochberg
Publikováno v:
iScience, Vol 25, Iss 5, Pp 104199- (2022)
Summary: Aging research is unparalleled in the breadth of disciplines it encompasses, from evolutionary studies examining the forces that shape aging to molecular studies uncovering the underlying mechanisms of age-related functional decline. Despite
Externí odkaz:
https://doaj.org/article/b80faeaf247e401282c9a01788bd15ad
Publikováno v:
Evolutionary Applications, Vol 13, Iss 7, Pp 1558-1568 (2020)
Abstract The utility of intratumour heterogeneity as a prognostic biomarker is the subject of ongoing clinical investigation. However, the relationship between this marker and its clinical impact is mediated by an evolutionary process that is not wel
Externí odkaz:
https://doaj.org/article/71fcb79e2d754931b365f89daae7b7c3
Publikováno v:
iScience, Vol 24, Iss 7, Pp 102710- (2021)
Summary: Lockdowns and stay-at-home orders have partially mitigated the spread of Covid-19. However, en masse mitigation has come with substantial socioeconomic costs. In this paper, we demonstrate how individualized policies based on disease status
Externí odkaz:
https://doaj.org/article/2446d6640d7f4cf894e6198c1632a49c
Autor:
Robert J. Noble, Viola Walther, Christian Roumestand, Michael E. Hochberg, Urszula Hibner, Patrice Lassus
Publikováno v:
Frontiers in Ecology and Evolution, Vol 9 (2021)
Explaining the emergence and maintenance of intratumor heterogeneity is an important question in cancer biology. Tumor cells can generate considerable subclonal diversity, which influences tumor growth rate, treatment resistance, and metastasis, yet
Externí odkaz:
https://doaj.org/article/f49cf3321ef847b0a531a171088e8739
Autor:
Katarina Bacevic, Robert Noble, Ahmed Soffar, Orchid Wael Ammar, Benjamin Boszonyik, Susana Prieto, Charles Vincent, Michael E. Hochberg, Liliana Krasinska, Daniel Fisher
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Adaptive therapy aims to control tumours by exploiting competition between therapy-sensitive and resistant cells. Here, the authors show that tumour spatial structure is a critical parameter for adaptive therapy as competition for space increases fit
Externí odkaz:
https://doaj.org/article/319e6d8db9064cf9bdccfcfa5db86330
Autor:
Michael E. Hochberg, James H. Brown
Publikováno v:
Ideas in Ecology and Evolution, Vol 7, Iss 1 (2015)
n/a
Externí odkaz:
https://doaj.org/article/a4ef110305fd489b87be4f553744145a
Autor:
Michael E. Hochberg
Publikováno v:
Ideas in Ecology and Evolution, Vol 7, Iss 1 (2015)
I argue that the quality of both scientific research and how it is communicated is maintained and improved through a process analogous to Darwinian evolution. Maintaining status quo or achieving scientific advances are potentially threatened by ‘co
Externí odkaz:
https://doaj.org/article/7e11b291b5c74c3caa717e30d2d170d9
Autor:
Michael E. Hochberg
Publikováno v:
Frontiers in Science. 1
Bacteria release and sense small molecules called autoinducers (AIs) in a process known as ‘quorum sensing’ (QS). The prevailing interpretation of QS is that by sensing AI concentrations, bacteria estimate population density to regulate the expre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7f8711d6fb4e2e7fd395df3ff1be862
https://doi.org/10.1101/2022.03.16.481998
https://doi.org/10.1101/2022.03.16.481998