Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Michael E. Cox"'
Autor:
Abigail Cunningham, Maddisen Brown, Jonathan Dresselhuis, Nicole Robinson, Keni Hervie, Michael E. Cox, Julia Mills
Publikováno v:
Biology, Vol 12, Iss 7, p 906 (2023)
In cancer cells, inhibition of integrin-linked kinase (ILK) increases centrosome declustering causing mitotic arrest and cell death. Yet, not all cancer cells are susceptible to anti-ILK treatment alone. We investigate a combination drug strategy tar
Externí odkaz:
https://doaj.org/article/937b224d9f4e4206966966f196b8b3cb
Publikováno v:
Pharmaceutics, Vol 13, Iss 9, p 1509 (2021)
There have been several studies that have linked elevated scavenger receptor class b type 1 (SR-B1) expression and activity to the development and progression of castration-resistant prostate cancer (CRPC). SR-B1 facilitates the influx of cholesterol
Externí odkaz:
https://doaj.org/article/c572c409c9c144f288db844464ca3bfd
Autor:
Manju Sharma, Corey Levenson, John C. Browning, Emily M. Becker, Ian Clements, Paul Castella, Michael E. Cox
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Cyclic adenosine monophosphate phosphodiesterases (PDEs) regulate pro-inflammatory cytokine production. One isoform, PDE4, is overactive in chronic relapsing inflammatory skin diseases: psoriasis and eczema/atopic dermatitis, and in several cancers.
Externí odkaz:
https://doaj.org/article/a28e5b3722344c0c82d0f6ad50edb97c
Publikováno v:
Ecology and Society, Vol 20, Iss 1, p 32 (2015)
The framework for analyzing sustainability of social-ecological systems (SES) framework of Elinor Ostrom is a multitier collection of concepts and variables that have proven to be relevant for understanding outcomes in diverse SES. The first tier of
Externí odkaz:
https://doaj.org/article/a39103dda7f74e8f832af9678829b874
Autor:
Mills, Abigail Cunningham, Maddisen Brown, Jonathan Dresselhuis, Nicole Robinson, Keni Hervie, Michael E. Cox, Julia
Publikováno v:
Biology; Volume 12; Issue 7; Pages: 906
In cancer cells, inhibition of integrin-linked kinase (ILK) increases centrosome declustering causing mitotic arrest and cell death. Yet, not all cancer cells are susceptible to anti-ILK treatment alone. We investigate a combination drug strategy tar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::07cfe1add524662bf70243f02a9c33a4
Autor:
Michael E. Cox, Alexander Levitzki, Martin E. Gleave, Haruhito Azuma, Ladan Fazli, Mitali Pandey, Hadas Reuveni, Mazyar Ghaffari, Naokazu Ibuki
Supplementary Table and Figures: Table S1: Prostate cancer tumor microarray characteristics Fig. S1: IRS antibody validation Fig. S2: Effect of NT157 on the viability of benign prostatic cell line Fig. S3: Immunoblot analysis of cell cycle markers Fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12899b36d256a918f07acb7d5c019e70
https://doi.org/10.1158/1535-7163.22502218
https://doi.org/10.1158/1535-7163.22502218
Autor:
Michael E. Cox, Kishor M. Wasan, Colm Morrissey, Peter S. Nelson, Collin C. Collins, Shancheng Ren, Yen-Yi Lin, Emma S. Tomlinson Guns, Hans H. Adomat, Gang Wang, Fatemeh Derakhshan, Ankur Midha, Jake W. Noble, Jacob A. Gordon
Aberrant cholesterol metabolism is increasingly appreciated to be essential for prostate cancer initiation and progression. Transcript expression of the high-density lipoprotein-cholesterol receptor scavenger receptor B1 (SR-B1) is elevated in primar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::971b2fbddc65e3ca834ce740246a0d31
https://doi.org/10.1158/0008-5472.c.6510765
https://doi.org/10.1158/0008-5472.c.6510765
Autor:
Michael E. Cox, Kishor M. Wasan, Colm Morrissey, Peter S. Nelson, Collin C. Collins, Shancheng Ren, Yen-Yi Lin, Emma S. Tomlinson Guns, Hans H. Adomat, Gang Wang, Fatemeh Derakhshan, Ankur Midha, Jake W. Noble, Jacob A. Gordon
Supplementary information describing methods for cell culture, HDL assay,qPCR and western blotting analysis, steroid analysis and BLT-1 pharmacokinetic analysis. Supplemental statistical analysis of IHC samples and results of in vivo profiling of BLT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45cde30f0b2f0cdd0f33e5962962bd6b
https://doi.org/10.1158/0008-5472.22420821
https://doi.org/10.1158/0008-5472.22420821
Autor:
Ivan R. Nabi, Sam M. Wiseman, Samuel Leung, Hamid Masoudi, Sher-Ping Leung, Steven J. Jones, Simon K. Chan, Obi L. Griffith, Michael E. Cox, Liliana D. Kojic, Jacky G. Goetz, Scott S. Strugnell, Bharat Joshi
Supplementary Movie 2 from Phosphorylated Caveolin-1 Regulates Rho/ROCK-Dependent Focal Adhesion Dynamics and Tumor Cell Migration and Invasion
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57354f8cf81d601048ac36e86eeb2934
https://doi.org/10.1158/0008-5472.22374251
https://doi.org/10.1158/0008-5472.22374251
Autor:
Johann S. de Bono, Leon W.M.M. Terstappen, Michael E. Cox, Arturo Molina, Colin S. Cooper, Stan B. Kaye, David Dearnaley, Christopher Parker, Craig P. Carden, Ronald Sipkema, Emilda Thompson, Charles Jameson, George Hawche, Nikhil Babu Oommen, Ruth Riisnaes, Joana Moreira, Frank Coumans, Rianne Levink, Roger A'Hern, Elaine Vickers, Alison H.M. Reid, David Olmos, Joost F. Swennenhuis, Gerhardt Attard
Supplementary Figures 1-3 from Characterization of ERG, AR and PTEN Gene Status in Circulating Tumor Cells from Patients with Castration-Resistant Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a42ec8a2fcd8f421aa2ba7ce00236fe
https://doi.org/10.1158/0008-5472.22379577.v1
https://doi.org/10.1158/0008-5472.22379577.v1